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DNA Optical Readout Methods

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Handbook of Biochips

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Abstract

On-chip optical DNA detection strategies are presented from the viewpoint of biochip technology. Technical requirements and solutions of fluorescence-based and other on-chip optical DNA detection schemes are discussed. Good separation of the target signal from the background (such as excitation light) is essential for successful detection. Further, CMOS-based sensor technologies are briefly discussed.

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Author information

Authors and Affiliations

  1. Graduate School of Materials Science, Nara Institute of Science and Technology, 8916-5 Takayama-cho, Ikoma, Nara, 630-0192, Japan

    Takashi Tokuda

  2. Division of Materials Science, Graduate School of Materials Science, Nara Institute of Science and Technology (NAIST), Ikoma, Nara, Japan

    Jun Ohta

Authors
  1. Takashi Tokuda
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  2. Jun Ohta
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Corresponding author

Correspondence to Takashi Tokuda .

Editor information

Editors and Affiliations

  1. Cutting-edge Net of Biomedical Research And INnovation (CenBRAIN) School of Engineering, Westlake University, Hangzhou, Zhejiang, China

    Mohamad Sawan

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Tokuda, T., Ohta, J. (2022). DNA Optical Readout Methods. In: Sawan, M. (eds) Handbook of Biochips. Springer, New York, NY. https://doi.org/10.1007/978-1-4614-3447-4_10

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