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Dermatophyte Antigens and Cell-Mediated Immunity in Dermatophytosis

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Current Topics in Medical Mycology

Part of the book series: Current Topics in Medical Mycology ((CT MYCOLOGY,volume 1))

Abstract

Recent advances in immunology have increased our present knowledge of host-parasite relationships in human dermatophytosis. Evidence is now accumulating regarding the importance of cell-mediated immunity (CMI) in the eradication of cutaneous infections. Thus, the main theme of this chapter will be cell-mediated responses and their different facets as expressed by delayed skin hypersensitivity reactions, in vitro lymphocyte reactivity, and to some extent T- cell function. These parameters will be considered in relationship to the clinical and mycologic aspects of dermatophyte infections in an attempt to establish the clinical significance of CMI. Furthermore, the important—but sometimes neglected—problems concerning the dermatophyte antigen and its production and standardization will be considered in some detail. All of these topics will be discussed using personal observations and previous research experience.

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  1. Taavi Kaaman
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  1. Department of Microbiology and Immunology, Chapel Hill, North Carolina, USA

    Michael R. McGinnis

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Kaaman, T. (1985). Dermatophyte Antigens and Cell-Mediated Immunity in Dermatophytosis. In: McGinnis, M.R. (eds) Current Topics in Medical Mycology. Current Topics in Medical Mycology, vol 1. Springer, New York, NY. https://doi.org/10.1007/978-1-4613-9547-8_4

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  • DOI: https://doi.org/10.1007/978-1-4613-9547-8_4

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