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Hair Restoration

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Evaluation and Treatment of the Aging Face

Abstract

Androgenetic alopecia, or common baldness, occurs widely in both women and men, basically through the same underlying mechanisms. Circulating androgens enter susceptible cells of the hair follicle and are transported through the cytosol to the nucleus, where combination of androgen with the cell’s genetic material takes place.2 The net effect is an eventual slowing or inhibition of hair growth, possibly through interference with the cell’s high-energy transfer systems, which are critical to rapid protein production.3 Continued androgen action over time and through repeated hair growth cycles results in a shrinkage or miniaturization of the hair follicle, and the hair that is elaborated by the follicle becomes fine and eventually almost invisible.

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References

  1. Price VH. Testosterone metabolism in the skin: a review of its function in androgenetic alopecia, acne vulgaris, and idiopathic hirsutism including recent studies with antiandrogens. Arch Dermatol. 1975;111:1496–1502.

    Article  CAS  PubMed  Google Scholar 

  2. Sawaya ME, Mendex AJ, Hsia SL. Translocation of androgen-receptor protein complex into nuclei of hair follicles and sebaceous glands from human scalp. J Invest Dermatol. 1988;90:605.

    Google Scholar 

  3. Kasick JM, Bergfeld WF, Steck WD, Gupta MK. Adrenal androgenic female-pattern alopecia: sex hormones and the balding woman. Cleve Clin Q. 1983;50:111–122.

    CAS  PubMed  Google Scholar 

  4. Cotsarelis G, Sun T-T, Lavker RM. Label-retaining cells reside in the bulge area of pilosebaceous unit: implications for follicular stem cells, hair cycle, and skin carcinogenesis. Cell. 1990;61:1329–1337.

    Article  CAS  PubMed  Google Scholar 

  5. Sun T-T, Cotsarelis G, Lavker RM. Hair follicular stem cells: the bulge-activation hypothesis. J Invest Dermatol. 1991;96: 77S–78S.

    Article  CAS  PubMed  Google Scholar 

  6. Kuster W, Happle R. The inheritance of common baldness: two B or not two B? J Am Acad Dermatol. 1984;11:921–926.

    Article  CAS  PubMed  Google Scholar 

  7. Hamilton JB. Male hormone stimulation is prerequisite and an incitant in common baldness. Am J Anat. 1942;71:451–480.

    Article  Google Scholar 

  8. Sawaya ME, Price VH, Harris IA, Kirsner RS, Hsia SL. Human hair follicle aromatase activity in females with androgenetic alopecia. J Invest Dermatol. 1990;94:575.

    Google Scholar 

  9. Venning VA, and Dawber RPR. Patterned androgenic alopecia in women. J Am Acad Dermatol. 1988;18:1073–1077.

    Article  CAS  PubMed  Google Scholar 

  10. Hamilton JB. Patterned loss of hair in man: Types and incidence. An New York Acad Sci. 1951;53:708–727.

    Article  CAS  Google Scholar 

  11. Okuda S. Clinical and experimental studies of transplantation of living hairs. Japan J Dermatol Urol. 1939;46:135–138.

    Google Scholar 

  12. Orentreich N. Autografts in alopecias and other selected dermatological conditions. An New York Acad Sci. 1959;83:463–478.

    Article  CAS  Google Scholar 

  13. Sasagawa M. Hair transplantation. Japan J Dermatol. 1930;30:493.

    Google Scholar 

  14. Fujita K. Reconstruction of eyebrow. La Lepro. 1953;22:364.

    Google Scholar 

  15. Marritt E. Transplantation of single hairs from the scalp as eyelashes. Review of the literature and a case report. J Dermatol Surg Oncol. 1980;6:271–273.

    CAS  PubMed  Google Scholar 

  16. Stough DB, Nelson BR, Stough DB. Incisional slit grafting. J Dermatol Surg Oncol. 1991; 17:243–253.

    Google Scholar 

  17. Vallis CP. Surgical treatment of receding hairline: report of a case. Plast Reconstr Surg. 1964;33:243–252.

    Google Scholar 

  18. Coiffman F. Use of square scalp grafts for male pattern baldness. Plast Reconstr Surg. 1977;60:228–232.

    Article  CAS  PubMed  Google Scholar 

  19. Brandy DA. A new instrument for the expedient production of minigrafts. 1992;18:487–492.

    CAS  Google Scholar 

  20. Stough DB, Schauder CS, Chu TP, Nelson BR. Linear grafting, a novel technique for hair transplantation. J Cosmetic Dermatol. 1993;6:49–52.

    Google Scholar 

  21. Blanchard G, Blanchard B. La reduction de la tonsure: concept nouveau dans le traitement chirurgical de la calvitie. L’Union Mèdicale du Canada. 1976;105:618–624.

    CAS  PubMed  Google Scholar 

  22. Blanchard G, Blanchard B. Obliteration of alopecia by hair lifting: a new concept and technique. J Nat Med Assoc. 1977;69:639–641.

    CAS  Google Scholar 

  23. Unger MG, Unger WP. Management of alopecia of the scalp by a combination of excisions and transplantations. J Dermatol Surg Oncol. 1978;4:670–672.

    CAS  PubMed  Google Scholar 

  24. Bosley LL, Hope CR, Montroy RE. Male pattern reduction (MPR) for surgical reduction of male pattern baldness. Curr Ther Res. 1979;25:281–287.

    Google Scholar 

  25. Alt TH. Scalp reduction as an adjunct to hair transplantation, review of relevant literature, presentation of an improved technique. J Dermatol Surg Oncol. 1980;6:1011–1018.

    CAS  PubMed  Google Scholar 

  26. Alt TH. Scalp reduction. Cosmetic Surg. 1981;1:1–19.

    Google Scholar 

  27. Norwood OT, Shiell RC. Scalp reductions. In: Hair Transplant Surgery, OT Norwood, ed. Charles C. Thomas, Springfield, 1984, pp. 160–200.

    Google Scholar 

  28. Fleming RW, Kabaker SS, Marritt M, Mayer TG. Panel discussion. Sixth National Symposium on Hair Replacement Surgery. Palm Springs, California, March 29, 1984.

    Google Scholar 

  29. Nordstrom REA. Change of direction of hair growth. J Dermatol Surg Oncol. 1983;9:156–158.

    CAS  PubMed  Google Scholar 

  30. Marzola M. An alternative hair replacement method. In: Hair Transplant Surgery, 2nd ed., OT Norwood, RC Shiell, ed. Charles C. Thomas, Springfield, 1984, pp. 163–200.

    Google Scholar 

  31. Brandy DA. The effectiveness of occipital artery ligations as a priming procedure for extensive scalp lifting. J Dermatol Surg Oncol. 1991;17:946–949.

    CAS  PubMed  Google Scholar 

  32. Lamont ES. A plastic surgical transformation: report of a case. West J Surg Obstet Gynecol. 1957;65:164–165.

    CAS  PubMed  Google Scholar 

  33. Juri J. Use of parieto-occipital flaps in the surgical treatment of baldness. Plast Reconst Surg. 1975;55:456–460.

    Article  CAS  PubMed  Google Scholar 

  34. Elliott, RA. Lateral scalp flaps for instant results in male pattern baldness. Plast Reconst Surg. 1977;60:699–703.

    Article  PubMed  Google Scholar 

  35. Nataf J. Special techniques of hair transplantation by fusiform grafts and flaps of many types. J Dermatol Surg Oncol. 1979;5:620–624.

    CAS  PubMed  Google Scholar 

  36. Ohmori K. Recent advances in the use of free flaps. An Chir Gynaecol. 1982;71:34–37.

    CAS  Google Scholar 

  37. Stough DB, Cates JA. Transposition flaps for the correction of baldness: a practical office procedure. J Dermatol Surg Oncol. 1980;6:286–289.

    PubMed  Google Scholar 

  38. Stough DB, Freilich IW. Hairbearing flaps for baldness. Fac Plast Surg. 1985;2:283–285.

    Article  Google Scholar 

  39. Wright MR. Psychological evaluation of a cosmetic surgical patient. In: Cosmetic Surgery of the Skin, WP Coleman, CW Hanke, eds. B.C. Decker Inc., Philadelphia, 1991, pp. 373–379.

    Google Scholar 

  40. Cotterill PC, Unger WP. Hair transplantation in females. J Dermatol Surg Oncol. 1992;18: 477–481.

    CAS  PubMed  Google Scholar 

  41. Beeson WH. Facial analysis. In: Aesthetic Surgery of the Aging Face, WH Beeson, EG McCollough, eds. C.V. Mosby Company, St. Louis, 1986, pp. 1–5.

    Google Scholar 

  42. Frechet P. A new method for correction of the vertical scar observed following scalp reduction for extensive alopecia. J Dermatol Surg Oncol. 1990;16:640–644.

    CAS  PubMed  Google Scholar 

  43. Schauder CS, Stough DB. Modified S pattern for scalp reduction. Am J Cosmet Surg. 1992;9:309–313.

    Google Scholar 

  44. Norwood OT, Shiell RC. Hair Transplant Surgery, 2nd ed. Charles C Thomas, Springfield, 1984, pp. 5–10.

    Google Scholar 

  45. Kabaker S. Experiences with parieto-occipital flaps in hair transplantation. Laryngoscope. 1978;88:73–84.

    CAS  PubMed  Google Scholar 

  46. Fleming RW, Mayer TG. Short vs. long flaps in the treatment of male pattern baldness. Arch Otolaryngol. 1981;107:403–408.

    Article  CAS  PubMed  Google Scholar 

  47. Price VH, Menefee E. Quantitative estimation of hair growth I. Androgenetic alopecia in women: effect of minoxidil. J Invest Dermatol. 1990;95:683–687.

    Article  CAS  PubMed  Google Scholar 

  48. Diani AR, Mulholland MJ, Shull KL, Kubicek MF, Johnson GA, Schostarez HJ, Brunden MN, Buhl AE. Hair growth effects of oral administration of finasteride, a steroid 5-alpha-reductase inhibitor, alone and in combination with topical minoxidil in the balding stumptail macaque. J Clin Endocrinol Metab. 1992;74:345–350.

    Article  CAS  PubMed  Google Scholar 

  49. Rittmaster RS. Topical anti-androgens in the treatment of male pattern baldness. Clin Dermatol. 1988;6:122–128.

    Article  CAS  PubMed  Google Scholar 

  50. Bazzano GS, Terezakis N, Galen W. Topical tretinoin for hair growth promotion. JAAS. 1986:15:880–883.

    CAS  Google Scholar 

  51. Burke BM, Cunliffe WJ. Oral spironolactone therapy for female patients with acne, hirsutism or androgenic alopecia. Br J Dermatol. 1985;112:124–125.

    Article  CAS  PubMed  Google Scholar 

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Authors
  1. D. Bluford Stough
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  2. Craig S. Schauder
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Editor information

Editors and Affiliations

  1. The Dermatology Center, Inc., 4535 Harding Road, 37205-2120, Nashville, TN, USA

    Melvin L. Elson M.D.

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© 1995 Springer-Verlag New York Inc.

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Stough, D.B., Schauder, C.S. (1995). Hair Restoration. In: Elson, M.L. (eds) Evaluation and Treatment of the Aging Face. Springer, New York, NY. https://doi.org/10.1007/978-1-4613-8401-4_13

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  • DOI: https://doi.org/10.1007/978-1-4613-8401-4_13

  • Publisher Name: Springer, New York, NY

  • Print ISBN: 978-1-4613-8403-8

  • Online ISBN: 978-1-4613-8401-4

  • eBook Packages: Springer Book Archive

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