Abstract
The renal tubular handling of calcium is essentially a filtered load-tubular reabsorption process. Micropuncture studies in the last few years have considerably expanded our knowledge of the reabsorptive system at different nephron segments available to free flow micropuncture of surface tubules (Sutton & Dirks, 1975). A considerable focus of these studies has been to relate Ca to Na reabsorption. More recent studies have been directed at assessing the effects of parathyroid hormone and Vitamin D metabolites, diuretics and physiological circumstances such as altered acidbase balance. The overall view that has developed is that the major bulk of filtered Ca is coupled proportionately with Na through direct or indirect mechanisms. However, the fine and independent control of Ca reabsorption takes place in the distal tubule and collecting ducts.
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Dirks, J.H., Quamme, G.A., Sutton, R.A.L. (1976). Tubular Handling of Calcium. In: Fleisch, H., Robertson, W.G., Smith, L.H., Vahlensieck, W. (eds) Urolithiasis Research. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-4295-3_8
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DOI: https://doi.org/10.1007/978-1-4613-4295-3_8
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