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Tricyclic and Monoamine-Oxidase-Inhibitor Antidepressants: Clinical Use

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Handbook of Psychopharmacology

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Abstract

Depression, despite the availability of a wide range of biological, pharmacological and psychological therapies, remains a major health problem. The social and economic cost, together with the immense personal and family suffering caused by this recurrent illness have stimulated a number of comparative studies to identify effective treatments. Although progress has undoubtedly been made and hundreds of reports on controlled and uncontrolled clinical trials, and review articles and chapters have been written on this subject (Cole, 1964; Cole and Davis, 1975), information regarding efficacy and choice of antidepressant drug management is surprisingly scant.

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References

  • Ananth, J., and Ruskin, R., 1974, Treatment of intractable depression, Int. Pharmacopsychiatry 9:218–229.

    PubMed  Google Scholar 

  • Angst, J., 1966, Zur Atiologie and Nosologie endogener depressiver, Psychosen. Monogr. Neurol. Psychiatr. 112:1–118.

    Google Scholar 

  • Angst, J., 1970, Clinical aspects of imipramine, in: Tofranil, Verlag Stamp Ai and Cie, AG, Berne.

    Google Scholar 

  • Angst, J., Baastrup, P., Grof, P., Hippius, H., Poldinger, W., and Weis, P., 1973, The course of monopolar depression and bipolar psychoses, Psychiatr. Neurol. Neurochir. 76:489–500.

    PubMed  Google Scholar 

  • Akindele, M. O., Evans, J. I., and Oswald, I., 1970, Monoamine oxidase inhibitors, sleep and mood, Electroenceph. Clin. Neurophysiol. 29:47–56.

    PubMed  Google Scholar 

  • Arnold, S. J., and Ginsburg, A., 1974, Enuresis: Treatment with imipramine, J. Am. Med. Assoc. 228:289–290.

    Google Scholar 

  • Asberg, M., 1974a, Individualization of treatment with tricyclic compounds, Med. Clin. North Am. 58:1083–1091.

    PubMed  Google Scholar 

  • Asberg, M., 1974b, Plasma nortriptyline levels-relationship to clinical effects, Clin. Pharmacol. Ther. 16:215–229.

    PubMed  Google Scholar 

  • Asberg, M., Cronholm, B., Sjoqvist, F., and Tuck, D., 1970, Correlation of subjective side effects with plasma concentrations of nortriptyline, Br. Med. J. 4:18–21.

    PubMed  Google Scholar 

  • Ascher, E., 1951/52, A criticism of the concept of neurotic depression, Am. J. Psychiatry 108:901–908.

    Google Scholar 

  • Ayd, F. J., 1974, Single daily dose of antidepressants, J. Am. Med. Assoc. 230:263–264.

    Google Scholar 

  • Ayuso Gutierrez, J. L., and Lopez-Ibor Alino, J. J., 1971, Tryptophan and an MAOI (Nialamide) in the treatment of depression. A double-blind study, Int. Pharmacopsychiatry 6:92–97.

    PubMed  Google Scholar 

  • Bethune, H. C., Burrell, R. H., Culpan, R. H., and Ogg, G. J., 1964, Vascular crisis associated with monoamine oxidase inhibitors, Am. J. Psychiatry 121:245–248.

    PubMed  Google Scholar 

  • Bornstein, P. E., Clayton, P. J., Halikas, J. A., Maurice, W. L., and Robins, E., 1973, The depression of widowhood after thirteen months, Br. J. Psychiatry 122:561–566.

    PubMed  Google Scholar 

  • Braithwaite, R. A., Goulding, R., Theano, G., Baily, J., and Coppen, H., 1972, Plasma concentration of amitriptyline and clinical response, Lancet 1:1297–1300.

    PubMed  Google Scholar 

  • Burks, J. S., Walker, J. E., Rumack, B. H., and Ott, T. E., 1974, Tricyclic antidepressant poisoning and reversal of coma, choreoathetosis, and myoclonus by physostigmine, J. Am. Med. Assoc. 230:1405–1407.

    Google Scholar 

  • Burrows, G. D., Davies, B., and Scoggins, B. A., 1972, Plasma concentration of nortriptyline and clinical response in depressive illness, Lancet 2:619–623.

    PubMed  Google Scholar 

  • Burrows, G. D., Scoggins, B. A., Turecek, L. R., and Davies, G., 1974, Plasma nortriptyline and clinical response, Clin. Pharmacol. Ther. 16:639–644.

    PubMed  Google Scholar 

  • Busfield, B. L., Schneller, P., and Capra, D., 1962, Depressive symptom or side effect? A comparative study of symptoms during pretreatment and treatment periods of patients on three antidepressant medications, J. Nero. Ment. Dis. 134:339–345.

    Google Scholar 

  • Cammer, L., 1973, Antidepressants as a prophylaxis against depression in the obsessive compulsive person, Psychosomatics 14:201–206.

    PubMed  Google Scholar 

  • Carney, M. W. P., Roth, M., and Garside, R. F., 1965, The diagnosis of depressive syndromes and the prediction of ECT response, Br. J. Psychiatry 111:659.

    PubMed  Google Scholar 

  • Cole, J. O., 1964, The therapeutic efficacy of antidepressant drugs: A review, J. Am. Med. Assoc. 190:448–455.

    Google Scholar 

  • Cole, J. O., and Davis, J. M., 1975, in: Antidepressant Drugs (A. M. Freedman, H. I. Kaplan, and B. J. Sadock, eds.), pp. 1941–1956, Williams and Wilkins, Baltimore.

    Google Scholar 

  • Coppen, A., Whybrow, P. C., Norguera, R., Maggs, R., and Prange, A. J., 1972, The comparative antidepressant value of L-tryptophan and imipramine with and without attempted potentiation by 1-liothyronine, Arch. Gen. Psychiatry 26:234–241.

    PubMed  Google Scholar 

  • Cowl, L., Lipman, R. S., Derogatis, L. R., Smith, J. E., and Pattison, J. H., 1974, Drugs and group psychotherapy in neurotic depression, Am. J. Psychiatry 131:191–198.

    Google Scholar 

  • Detre, T. P., and Jarecki, H. G., 1971, Modern Psychiatric Treatment, J. B. Lippincott, Philadelphia.

    Google Scholar 

  • Detre, T. P., Himmelhoch, J., Swartzburg, M., Anderson, C. M., Byck, R., and Kupfer, D. J., 1972, Hypersomnia and manic-depressive disease, Am. J. Psychiatry 128:1303–1305.

    PubMed  Google Scholar 

  • Drotar, D., 1974, Concern over the categorization of depression in children, J. Pediatr. 85:290–291.

    PubMed  Google Scholar 

  • Dunleavy, D. L., and Oswald, I., 1973, Phenelzine, mood response, and sleep, Arch. Gen. Psychiatry 28:353–356.

    PubMed  Google Scholar 

  • Fawcett, J., 1975, Biochemical and neuropharmacological research, in: Depression and Human Existence (E. J. Anthony and T. Benedek, eds.), pp. 21–52, Little Brown and Company, Boston.

    Google Scholar 

  • Feighner, J. P., King, L. J., Schuckit, M. A., Croughan, J., and Briscoe, W., 1972, Hormonal potentiation of imipramine and ECT in primary depression, Am. J. Psychiatry 128:1230–1238.

    PubMed  Google Scholar 

  • Friedman, A. S., 1975, Interaction of drug therapy with marital therapy in depressive patients, Arch. Gen. Psychiatry 32:619–637.

    PubMed  Google Scholar 

  • Gittelman-Klein, R., and Klein, D. R., 1972, School phobia: Diagnostic consideration in the light of imipramine effects in drugs, development, in: Cerebral Function (W. L. Smith, ed.), pp. 200–223, Charles C. Thomas, Springfield, Illinois.

    Google Scholar 

  • Glassman, A. H., Kantor, S. J., and Shostak, M., 1975, Depression, delusions and drug response, Am. J. Psychiatry 132:716–719.

    PubMed  Google Scholar 

  • Goel, K. M., and Shanks, R. A., 1974, Amitriptyline and imipramine poisoning in children, Br. Med. J. 1:261–263.

    PubMed  Google Scholar 

  • Goldberg, H. L., Finnerty, R. J., Nathan, L., and Cole, J. O., 1974, Doxepin in a single bedtime dose in psychoneurotic outpatients, Arch. Gen. Psychiatry 31:513–517.

    PubMed  Google Scholar 

  • Gomersall, J. D., and Stuart, A., 1973, Amitriptyline in migraine prophylaxis, J. Neurol. Neurosurg. Psychiatry 36:684–690.

    PubMed  Google Scholar 

  • Greenberg, L. M., Yellin, A. M., Spring, C., and Metcalf, M., 1975, Clinical effects of imipramine and methylphenidate in hyperactive children, Int. J. Ment. Health 4:144–156.

    Google Scholar 

  • Grof, P., Saxena, B., Cantor, R., Kaigle, L., Hetherington, D., and Haines, T., 1974, Doxepin versus amitriptyline in depression: A sequential double-blind study, Curr. Ther. Res. 16:470–476.

    PubMed  Google Scholar 

  • Guilleminault, C., Carskadon, M., Dement, W. C., 1974, On the treatment of rapid eye movement narcolepsy, Arch. Neurol. 30:90–93.

    PubMed  Google Scholar 

  • Guze, S. B., Woodruff, R. A., and Clayton, P. J., 1971, Secondary affective disorder: A study of 95 cases, Psychol. Med. 1:426–428.

    PubMed  Google Scholar 

  • Hamilton, M., and White, J. M., 1959, Clinical syndromes in depressive states, J. Ment. Sci. 105:985.

    PubMed  Google Scholar 

  • Haskell, D. S., Dimascio, A., and Prusoff, B., 1975, Rapidity of symptom reduction in depressions treated with amitriptyline, J. Neru. Ment. Dis. 160:24–33.

    Google Scholar 

  • Hayes, T. A., Panitch, M. L., and Barker, E., 1975, Imipramine dosage in children: A comment on “imipramine and electrocardiographic abnormalities in hyperactive children,” Am. J. Psychiatry 132:546–547.

    PubMed  Google Scholar 

  • Herzog, A., and Detre, T., 1974, Postpartum psychoses, Dis. Nerv. Syst. 35:231–236.

    Google Scholar 

  • Himmelhoch, J. M., Detre, T. P., Kupfer, D. J., Swartzburg, M., and Byck, R., 1972, Treatment of previously intractable depressions with tranylcypromine and lithium, J. Nero. Ment. Dis. 155:216–220.

    Google Scholar 

  • Hippius, H., 1972, The current status of treatment for depression, in: Depressive Illness, Diagnosis, Assessment, Treatment (P. Keilholz, ed.), pp. 49–58, H. Huber, Bern.

    Google Scholar 

  • Hollister, L. E., 1974, Doxepin hydrochloride, Ann. Intern. Med. 81:360–363.

    PubMed  Google Scholar 

  • Hollister, L. E., Overall, J. E., and Johnson, M. H., 1966, Amitriptyline alone and combined with perphenazine in newly admitted depressed patients, J. New. Ment. Dis. 142:460–469.

    Google Scholar 

  • Jacobsson, L., Glitterstam, K., and Palm, U., 1974, Objective assessment of anticholinergic side effects of tricyclic antidepressants, Acta Psychiatr. Scand. Suppl. 255:47–53.

    PubMed  Google Scholar 

  • Johnstone, E. C., and Marsh, W., 1973, Acetylator status and response to phenelzine in depressed patients, Lancet 1:567–570.

    PubMed  Google Scholar 

  • Kay, D. W. K., Fahy, T., and Garside, R. F., 1970, A seven-month double-blind trial of amitriptyline and diazepam in ECT treated depressed patients, Br. J. Psychiatry 117:667.

    PubMed  Google Scholar 

  • Kay, D. W. K., Garside, R. F., and Fahy, T. J., 1973, A double-blind trial of phenelzine and amitriptyline in depressed out-patients. A possible differential effect of the drugs on symptoms, Br. J. Psychiatry 123:63–67.

    PubMed  Google Scholar 

  • Kiloh, L. G., and Garside, R. F., 1963, The independence of neurotic depression and endogenous depression, Br. J. Psychiatry 109:451.

    PubMed  Google Scholar 

  • Kiloh, L. G., Ball, J. R. B., and Garside, R. F., 1962, Prognostic factors in treatment of depressive states with imipramine, Br. Med. J. 1:1225–1227.

    PubMed  Google Scholar 

  • Klein, D. F., 1964, Delineation of two-drug responsive anxiety syndromes, Psychopharmacologa 5:397.

    Google Scholar 

  • Klein, D. F., 1974, Endogenomorphic depression. A conceptual and terminological revision, Arch. Gen. Psychiatry 31:447–454.

    PubMed  Google Scholar 

  • Klein, D. F., and Davis, J. M., 1969, Diagnosis and Drug Treatment of Psychiatric Disorders, Williams and Wilkins, Baltimore.

    Google Scholar 

  • Klerman, G. L., Dimascio, A., Weissman, M., Prusoff, B., and Paykel, E. S., 1974, Treatment of depression by drugs and psychotherapy, Am. J. Psychiatry 131:186–191.

    PubMed  Google Scholar 

  • Kotin, J., Post, R. M., and Goodwin, F. K., 1973, Drug treatment of depressed patients referred for hospitalization, Am. J. Psychiatry 130:1139–1141.

    PubMed  Google Scholar 

  • Kraeplin, E., 1921, Manic Depressive Insanity and Paranoia, E. S. Livingstone, Edinburgh.

    Google Scholar 

  • Kragh-Sorensen, P., Hansen, C. E., and Asberg, M., 1973, Plasma levels of nortriptyline in the treatment of endogenous depression, Acta Psychiatr. Scand. 49:444–456.

    PubMed  Google Scholar 

  • Kragh-Sorensen, P., Hansen, C. E., Larsen, N. E., Naestoft, J., and Hvidberg, E. F., 1974, Long-term treatment of endogenous depression with nortriptyline with control of plasma levels, Psychol. Med. 4:174–180.

    PubMed  Google Scholar 

  • Kupeer, D. J., and Detre, T. P., 1971, Once more on the extraordinary side effects of drugs, Clin. Pharmacol. Ther. 12:575–582.

    Google Scholar 

  • Kupfer, D. J., and Foster, F. G., 1975, The sleep of psychotic patients: Does it all look alike? in: Biology of the Major Psychoses: A Comparative Analysis (D. X. Freedman, ed.), pp. 143–159, Raven Press, New York.

    Google Scholar 

  • Kupfer, D. J., Detre, T. P., and Himmelhoch, J., 1973, Classification of depression. A guide for the clinician. Symposium: Advances in the Treatment of Affective Disturbances, Rutgers University, New Brunswick, New Jersey.

    Google Scholar 

  • Kupfer, D. J., Pickar, D., Himmelhoch, J. M., and Detre, T. P., 1975a, Are there two types of unipolar depression?, Arch. Gen. Psychiatry 32:886–891.

    Google Scholar 

  • Kupfer, D. J., Foster, F. G., Detre, T. P., and Himmelhoch, J., 1975b, Sleep EEG and motor activity as indicators in affective states, Neuropsychobiology 1:296–303.

    PubMed  Google Scholar 

  • Leonhard, K., Koref, I., Schulz, H., 1962, Temperament in families with monopolar and bipolar phasic psychoses, Psychiatr. Neurol. (Basel) 143:416.

    Google Scholar 

  • Levine, J., and Raskin, A., 1974, Predicting treatment responsiveness-resistiveness in a population of depressed patients, Pharmakopsychiatrie 7:217–222.

    Google Scholar 

  • Lingjaerde, O., Edlund, A. H., Gormsen, C. A., Gottfries, C. G., Haugstad, A., Hermann, I. L., Hollnagel, P., Makimattila, A., Rasmussen, K. E., Remvig, J., and Robak, O. H., 1974, The effect of lithium carbonate in combination with tricyclic antidepressants in endogenous depression. A double-blind, multicenter trial, Acta Psychiatr. Scand. 50:233–242.

    PubMed  Google Scholar 

  • Lopez-Ibor Alino, J. J., Ayuso Gutierrez, J. L., and Montejo Iglesias, M. L., 1973, Tryptophan and amitriptyline in the treatment of depression, Int. Pharmacopsychiatry 8:145–151.

    Google Scholar 

  • Mapother, E., 1926, Discussion on manic-depressive psychosis, Br. Med. J. 2:872–879.

    Google Scholar 

  • Martin, G. I., and Zaug, P. J., 1975, Electrocardiographic monitoring of enuretic children receiving therapeutic doses of imipramine, Am. J. Psychiatry 132:540–542.

    PubMed  Google Scholar 

  • Mcclure, D. J., Low, G. L., and Gent, M., 1973, Clomipramine HCI-a double-blind study of a new antidepressant drug, Can. Psychiatr. Assoc. J. 18:403–408.

    PubMed  Google Scholar 

  • Medical Letter, 1974a, Imipramine for enuresis, Med. Lett. 16:22–24.

    Google Scholar 

  • Medical Letter, 1974b, Sunscreen, Med. Lett. 16:60.

    Google Scholar 

  • Medical Letter, 1975a, Antidepressant drugs, Med. Lett. 17:1–3.

    Google Scholar 

  • Medical Letter, 1975b, Adverse interactions of drugs, Med. Lett. 17:17.

    Google Scholar 

  • Mendels, J., and Digiacomo, J., 1973, The treatment of depression with a single daily dose of imipramine pamoate, Am. J. Psychiatry 130:1022–1024.

    PubMed  Google Scholar 

  • Mindham, R. H. S., Howland, C., and Shepherd, M., 1973, An evaluation of continuation therapy with tricyclic antidepressants in depressive illness, Psychol. Med. 3:5–17.

    PubMed  Google Scholar 

  • Morris, J. B., and Beck, A. T., 1974, The efficacy of antidepressant drugs, Arch. Gen. Psychiatry 30:667–674.

    PubMed  Google Scholar 

  • O’Regan, J. B., 1974, Hypersomnia and MAOI antidepressants, Can. Med. Assoc. J. 111:213.

    PubMed  Google Scholar 

  • Ossofsky, H. J., 1974, Endogenous depression in infancy and childhood, Camp. Psychiatry 15:19–25.

    Google Scholar 

  • Paykel, E. S., 1972, Depressive typologies and response to amitriptyline, Br. J. Psychiatry 120:147–156.

    PubMed  Google Scholar 

  • Paykel, E. S., Dimascio, A., Haskell, D., and Prusoff, B. A., 1975, Effects of maintenance amitriptyline and psychotherapy on symptoms of depression, Psychol. Med. 5:66–77.

    Google Scholar 

  • Perris, C., 1966, A study of bipolar (manic-depressive) and unipolar recurrent depressive psychoses, Acta Psychiatr. Scand. 42 (Suppl. 194):1–188.

    Google Scholar 

  • Perris, C., 1971, Personality patterns in patients with affective disorders, Acta Psychiatr. Scand. 47:43–50.

    Google Scholar 

  • Petti, T. A., and Campbell, M., 1975, Imipramine and seizures, Am. J. Psychiatry 132:538–540.

    PubMed  Google Scholar 

  • Prange, A. J., 1975, Pharmacotherapy of depression, in: The Nature and Treatment of Depression (F. F. Flach and S. C. Draghi, eds.), pp. 255–269, John Wiley & Sons, New York.

    Google Scholar 

  • Prange, A. J., Wilson, I. C., Knox, A., Mcclane, T. K., and Lipton, M. A., 1970, Enhancement of imipramine by thyroid stimulating hormone: Clinical and theoretical implications, Am. J. Psychiatry 127:191–199.

    PubMed  Google Scholar 

  • Prien, R. F., Klett, C. J., and Caffey, E. M., 1973, Lithium carbonate and imipramine in prevention of affective episodes, Arch. Gen. Psychiatry 29:420–425.

    PubMed  Google Scholar 

  • Quinn, P. O., and Rapoport, J. L., 1975, One-year follow-up of hyperactive boys treated with imipramine or methylphenidate, Am. J. Psychiatry 132:241–245.

    PubMed  Google Scholar 

  • Rapoport, J. L., Quinn, P. O., Bradbard, G., Riddle, K. D., and Brooks, E., 1974, Imipramine and methylphenidate treatments of hyperactive boys, Arch. Gen. Psychiatry 30:789–793.

    PubMed  Google Scholar 

  • Raskin, A., 1972, Adverse reactions to phenelzine: Results of a nine hospital depression study, J. Clin. Pharmacol. 12:22–25.

    Google Scholar 

  • Raskin, A., 1974, A guide for drug use in depressive disorders, Am. J. Psychiatry 131:181–185.

    PubMed  Google Scholar 

  • Raskin, A., Schulterbrandt, J. G., Reatig, N., and Mckeon, J. J., 1970, Differential response to chlorpromazine, imipramine, and placebo, Arch. Gen. Psychiatry 23:164–173.

    PubMed  Google Scholar 

  • Ravaris, C. L., Nies, A., Robinson, D. S., Ives, J. O., Lamborn, K. R., and Korson, L., 1976, A multiple dose, controlled study of phenelzine in depression-anxiety states, Arch. Gen. Psychiatry 33:347–350.

    PubMed  Google Scholar 

  • Rickels, K., Hutchinson, J. C., Weise, C. C., Csanalosi, I., Chung, M. R., and Case, W., 1972, Doxepin and amitriptyline-perphenazine in mixed anxious-depressed neurotic outpatients: A collaborative study, Psychopharmacologia 23:305–318.

    PubMed  Google Scholar 

  • Rickels, K., Weise, C. C., Csanalosi, I., Chung, H. R., Feldman, H. S., Resenfeld, H., and Whalen, E. M., 1974, Clomipramine and amitriptyline in depressed outpatients. A controlled study, Psychopharmacologia 34:361–376.

    PubMed  Google Scholar 

  • Robins, E., and Guze, S. B., 1972, Classification of affective disorders: The primary-secondary, the endogenous-reactive, and the neurotic-psychotic concepts, in: Recent Advances in the Psychobiology of Depressive Illnesses (T. A. Williams, M. M. Katz, and J. A. Shield, eds.), U.S. Govt. Printing Office, Washington, D.C.

    Google Scholar 

  • Robinson, D. S., Nies, A., Ravaris, C. L., and Lamborn, K. R., 1973, The monoamine oxidase inhibitor, phenelzine, in the treatment of depressive-anxiety states, Arch. Gen. Psychiatry 29:407–413.

    PubMed  Google Scholar 

  • Rosenthal, S., and Gudeman, J., 1967, The self-pitying constellation in depression, Br. J. Psychiatry 113:485–489.

    PubMed  Google Scholar 

  • Rosenthal, S. H., and Klerman, G. L., 1966, Content and consistency in the endogenous depressive pattern, Br. J. Psychiatry 112:471–484.

    Google Scholar 

  • Roth, M., and Myers, D. H., 1969, Anxiety neuroses and phobic states: II. Diagnosis and management, Br. Med. J. 1:559–562.

    PubMed  Google Scholar 

  • Safer, D., Allen, R., and Bart, E., 1972, Depression of growth in hyperactive children on stimulant drugs, N. Engl. J. Med. 287:217–220.

    PubMed  Google Scholar 

  • Sargent, W., 1961, Drugs in the treatment of depression, Br. Med. J. 1:225–227.

    Google Scholar 

  • Schuckit, M., Robins, E., and Feighner, J., 1971, Tricyclic antidepressants and monoamine oxidase inhibitors: Combination therapy in the treatment of depression, Arch. Gen. Psychiatry 24:509–514.

    PubMed  Google Scholar 

  • Schulterbrandt, J. G., Raskin, A., and Reatig, N., 1974, True and apparent side effects in a controlled trial of chlorpromazine and imipramine in depression, Psychopharmacologia 38:303–317.

    PubMed  Google Scholar 

  • Seager, C. P., and Bird, R. L., 1962, Imipramine with electrical treatment in depression: A controlled trial, J. Ment. Sci. 108:704–707.

    PubMed  Google Scholar 

  • Shaw, D. M., Johnson, A. L., and Macsweeney, D. A., 1972, Tricyclic antidepressants and tryptophan in unipolar affective disorder, Lancet 2:1245.

    PubMed  Google Scholar 

  • Snyder, B. D., Blonde, L., Mcwhirter, W. R., 1974, Reversal of amitriptyline intoxication by physostigmine, J. Am. Med. Assoc. 230:1433–1434.

    Google Scholar 

  • Spiker, D. G., and Pugh, D. D., 1976, Combining tricyclic and monoamine oxidase inhibitor antidepressants, Arch. Gen. Psychiatry 33:828–830.

    PubMed  Google Scholar 

  • Spiker, D. G., Weiss, A. N., Chang, S. S., Ruwitch, J. F., and Biggs, J. T., 1975, Tricyclic antidepressant overdose: Clinical presentation and plasma levels, Clin. Pharmacol. Ther. 18:539–546.

    PubMed  Google Scholar 

  • Strauss, J., 1973, Diagnostic models and the nature of psychiatric disorder, Arch. Gen. Psychiatry 29:445–449.

    PubMed  Google Scholar 

  • Taub, A., 1975, Factors in the diagnosis and treatment of chronic pain, J. Autism Child. Schizoph. 5:1–12.

    Google Scholar 

  • Teychenne, P. F., Calne, D. B., Lewis, P. J., and Findley, L. J., 1975, Interactions of levodopa with inhibitors of monoamine oxidase and L-aromatic amino acid decarboxyl-ase, Clin. Pharmacol Ther. 18:273–277.

    PubMed  Google Scholar 

  • Tyber, M. A., 1975, The relationship between hiatus hernia and tricyclic antidepressants: A report of five cases, Am. J. Psychiatry 132:652–653.

    PubMed  Google Scholar 

  • Waizer, J., Hoffman, S. P., Polizos, P., and Engelhardt, D. M., 1974, Outpatient treatment of hyperactive school children with imipramine, Am. J. Psychiatry 131:587–591.

    PubMed  Google Scholar 

  • Walker, R. D., Deture, F. A., Fennell, R. S., and Richard, G. A., 1974, Enuresis, diagnosis and management, J. Fla. Med. Assoc. 61:861–864.

    PubMed  Google Scholar 

  • Watts, C. A. H., 1957, The mild endogenous depression, Br. J. Med. 1:4–8.

    Google Scholar 

  • Weinberg, W. A., Rutman, J., Sullivan, L., Penick, E. C., and Dietz, S. G., 1973, Depression in children referred to an educational diagnostic center: Diagnosis and treatment. Preliminary report, J. Pediatr. 83:1065–1072.

    PubMed  Google Scholar 

  • Weissman, M. M., Klerman, G. L., Paykel, E. S., Prusoff, B., and Hanson, B., 1974, Treatment effects on the social adjustment of depressed patients, Arch. Gen. Psychiatry 30:771–778.

    PubMed  Google Scholar 

  • West, E. D., and Dally, T. J., 1959, Effects of iproniazid in depressive syndromes, Br. Med. J. 1:1491–1494.

    PubMed  Google Scholar 

  • Wheatley, D., 1972, Potentiation of amitriptyline by thyroid hormone, Arch. Gen. Psychiatry 26:229–233.

    PubMed  Google Scholar 

  • Whybrow, P. C., Coppen, A., Prange, A. J., Noguera, R., and Bailey, J. E., 1972, Thyroid function and the response to 1-iothyronine in depression, Arch. Gen. Psychiatry 26:242–245.

    PubMed  Google Scholar 

  • Winokur, G., Clayton, P. J., and Reich, T., 1969, Manic-Depressive Illness, C. V. Mosby, St. Louis, Missouri.

    Google Scholar 

  • Winsberg, B. G., Goldstein, S., Yepes, L. E., and Perel, J. M., 1975, Imipramine and electrocardiographic abnormalities in hyperactive children, Am. J. Psychiatry 132:542–545.

    PubMed  Google Scholar 

  • Woodruff, R. A., Goodwin, J. W., and Guze, S. B., 1974, Psychiatric Diagnosis, pp. 3–24, Oxford University Press, New York.

    Google Scholar 

  • Wyatt, R. J., Fram, D. H., Buchbinder, R., and Snyder, F., 1971a, Treatment of intractable narcolepsy with a monoamine oxidase inhibitor, New Engl. J. Med. 285:987–991.

    PubMed  Google Scholar 

  • Wyatt, R. J., Fram, D., Kupfer, D. J., and Snyder, F., 1971b, Total prolonged drug-induced rapid eye movement sleep suppression in anxious-depressed patients, Arch. Gen. Psychiatry 24:145–155.

    PubMed  Google Scholar 

  • Zall, H., 1971, Lithium carbonate and isocarboxazid-an effective drug approach in severe depression, Am. J. Psychiatry 127:136–139.

    Google Scholar 

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Author information

Authors and Affiliations

  1. Department of Psychiatry, University of Pittsburgh School of Medicine, and Western Psychiatric Institute and Clinic, Pittsburgh, Pennsylvania, USA

    David J. Kupfer & Thomas P. Detre

Authors
  1. David J. Kupfer
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  2. Thomas P. Detre
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Editor information

Editors and Affiliations

  1. Department of Pharmacology, University of Cambridge, UK

    Leslie L. Iversen

  2. Department of Psychology, University of Cambridge, UK

    Susan D. Iversen

  3. Departments of Pharmacology and Psychiatry, The Johns Hopkins University School of Medicine, USA

    Solomon H. Snyder

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© 1987 Plenum Press, New York

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Kupfer, D.J., Detre, T.P. (1987). Tricyclic and Monoamine-Oxidase-Inhibitor Antidepressants: Clinical Use. In: Iversen, L.L., Iversen, S.D., Snyder, S.H. (eds) Handbook of Psychopharmacology. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-4045-4_5

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  • DOI: https://doi.org/10.1007/978-1-4613-4045-4_5

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4613-4047-8

  • Online ISBN: 978-1-4613-4045-4

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