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The Brain and the Endocrine System: A Memoir

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Pioneers in Neuroendocrinology II

Part of the book series: Perspectives in Neuroendocrine Research ((PNR,volume 2))

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Abstract

I suppose my career first began to turn toward neuroendocrinology on December 7, 1941. At that time, I was majoring in government at Harvard College and planning to enter public administration. After the Japanese attack on Pearl Harbor, I was drafted and initially assigned to the infantry. However, the Army subsequently decided to send me back to school, first for pre-engineering studies and then for a premedical and medical education. The change from public administration to medical science is one I have never regretted, but it is one that occurred because of world events rather than personal planning.

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References

  • Assaykeen, T. A., Goldfien, A., Otsuka, K., and Ganong, W. F. (1969). Effect of a and ß blocking agents on the increase in plasma renin activity provoked in dogs by insulin- induced hypoglycemia. In Abstracts of the Fourth International Congress of Nephrology, p. 37.

    Google Scholar 

  • Barger, A. C., Berlin, R. D., and Tulenko, J. F. (1958). Infusion of aldosterone, 9-a- fluorohydrocortisone and anti-diuretic hormone into the renal artery of normal and adrenalectomized dogs: Effect on electrolyte and water excretion. Endocrinology 62:804.

    Article  PubMed  CAS  Google Scholar 

  • Biglieri, E. G., and Ganong, W. F. (1961). Effect of hypophysectomy on adrenocortical response to bilateral carotid constriction. Proc. Soc. Exp. Biol. Med. 106:806.

    CAS  Google Scholar 

  • Bloch, G. J., and Ganong, W. F. (1971). Lesions of the brain and the onset of puberty in the female rat. Endocrinology 89:898.

    Article  PubMed  CAS  Google Scholar 

  • Cowie, A. T., Ganong, W. F., and Hume, D. M. (1954). The eosinopenic response to graded doses of hydrocortisone in the adrenalectomized dog with and without surgical trauma. Endocrinology 55:745.

    Article  CAS  Google Scholar 

  • Dallman, M. F., Engeland, W. C., and Shinsako, J. (1976). Compensatory adrenal growth: A neurally mediated reflex. Am. J. Physiol. 231:408.

    PubMed  CAS  Google Scholar 

  • Davis, J. O., Carpenter, C. C. J., Ayers, C. R., Holman, J., and Bohn, R. C. (1961). Evidence for secretion of aldosterone-stimulating hormone by the kidney. J. Clin. Invest. 40:684.

    Article  PubMed  CAS  Google Scholar 

  • Farrell, G. (1958). Regulation of aldosterone secretion. Physiol. Rev. 38:709.

    PubMed  CAS  Google Scholar 

  • Ganong, W. F. (1954). The effect of ACTH on adrenal size in hypophysectomized rats after removal of one adrenal. Endocrinology 55:117.

    Article  PubMed  CAS  Google Scholar 

  • Ganong, W. F. (1974). The role of catecholamines and acetylcholine in the regulation of endocrine function. Life Sci. 15:1401.

    Article  PubMed  CAS  Google Scholar 

  • Ganong, W. F., and Hume, D. M. (1954). Absence of stress-induced and “compensatory” adrenal hypertrophy in dogs with hypothalamic lesions. Endocrinology 55:474.

    Article  PubMed  CAS  Google Scholar 

  • Ganong, W. F., and Hume, D. M. (1955). Effect of hypothalamic lesions on steroid-induced atrophy of adrenal cortex in dog. Proc. Soc. Exp. Biol. Med. 88:528.

    PubMed  CAS  Google Scholar 

  • Ganong, W. F., and Hume, D. M. (1956a). Concentration of ACTH in cavernous sinus and peripheral arterial blood in the dog. Proc. Soc. Exp. Biol. Med. 92:621.

    PubMed  CAS  Google Scholar 

  • Ganong, W. F., and Hume, D. M. (1956b). The effect of graded hypophysectomy on thyroid, gonadal, and adrenocortical function in the dog. Endocrinology 59:292.

    Google Scholar 

  • Ganong, W. F., and Mulrow, P. J. (1958). Rate of change in sodium and potassium excretion after injection of aldosterone into the aorta and renal artery of the dog.Am. J. Physiol. 195:337.

    PubMed  CAS  Google Scholar 

  • Ganong, W. F., and Mulrow, P. J. (1961). Evidence of secretion of an aldosterone-stimulating substance by the kidney. Nature (London ) 190:1115.

    Article  CAS  Google Scholar 

  • Ganong, W. F., Zucker, E., Clawson, C. K., Voss, E. C., Klotzbach, M. L., and Piatt, K. A. (1953). The early field diagnosis of epidemic hemorrhagic fever. Ann. Int. Med. 38:61.

    PubMed  CAS  Google Scholar 

  • Ganong, W. F., Fredrickson, D. S., and Hume, D. M. (1955). The effect of hypothalamic lesions on thyroid function in the dog.Endocrinology 57:355.

    Article  PubMed  CAS  Google Scholar 

  • Ganong, W. F., Lieberman, A. H., Daily, W. J. R., Yuen, V. S., Mulrow, P. J., Luetscher, J. A., Jr., and Bailey, R. E. (1959). Aldosterone secretion in dogs with hypothalamic lesions. Endocrinology 65:18.

    Article  PubMed  CAS  Google Scholar 

  • Ganong, W. F., Shepherd, M. D., Wall, J. R., Van Brunt, E. E., and Clegg, M. T. (1963). Penetration of light into the brain of mammals. Endocrinology 72:962.

    Article  PubMed  CAS  Google Scholar 

  • Ganong, W. F., Kramer, N., Salmon, J., Reid, I. A., Lovinger, R., Scapagnini, U., Boryczka, A. T., and Shackelford, R. (1976). Pharmacological evidence for inhibition of ACTH secretion by a central adrenergic system in the dog. Neuroscience 1:167.

    Article  PubMed  CAS  Google Scholar 

  • Gellert, R. J., and Ganong, W. F. (1960). Precocious puberty in rats with hypothalamic lesions.Acta Endocrinol. 33:569.

    PubMed  CAS  Google Scholar 

  • Gellert, R. J., Bass, E., Jacobs, C., Smith, R., and Ganong, W. F. (1964). Precocious vaginal opening and cornification in rats following injections of extracts of steer median eminence and pars tuberalis.Endocrinology 75:861.

    Article  PubMed  CAS  Google Scholar 

  • Genest, J., Bairon, T., Kiow, E., Nowaczynski, W., Boucher, R., and Chretien, M. (1961). Studies of pathogenesis of human hypertension: The adrenal cortex and renal pressor mechanism. Ann. Int. Med. 55:12.

    PubMed  CAS  Google Scholar 

  • de Groot, J., and Harris, G. W. (1950). Hypothalamic control of the secretion of adrenocorticotropic hormone. J. Physiol. 111:335.

    Google Scholar 

  • Hartroft, P. M., and Hartroft, W. S. (1955). Studies on renal juxtaglomerular cells. II. Correlation of the degree of granulation of juxtaglomerular cells with width of the zona glomerulosa of the adrenal cortex. J. Exp. Med. 102:205.

    Article  PubMed  CAS  Google Scholar 

  • Hume, D. M. (1949). The role of the hypothalamus in the pituitary-adrenal cortical response to stress. J. Clin. Invest. 28:790.

    Google Scholar 

  • Hume, D. M., and Ganong, W. F. (1956). A method for accurate placement of electrodes in the hypothalamus of the dog. Electroencephalogr. Clin. Neurophysiol. 8:136.

    Article  PubMed  CAS  Google Scholar 

  • Hume, D. M., and Wittenstein, D. J. (1950). The relationship of the hypothalamus to pituitary-adrenocortical function. In Mote, J. R. (ed.),Proceedings of the First Clinical ACTH Conference, Blakiston, Philadelphia, p. 134.

    Google Scholar 

  • Johnson, J. A., and Davis, J. O. (1973). Angiotensin II: Important role in the maintenance of arterial blood pressure. Science 179:906.

    Article  PubMed  CAS  Google Scholar 

  • Kragt, C. L., and Ganong, W. F. (1968). Pituitary FSH content in female rats at various ages. Endocrinology 82:1241.

    Article  CAS  Google Scholar 

  • Laragh, J. H., Angers, M., Kelly, W. G., and Lieberman, S. (1960). Hypotensive agents and pressor substances. J. Am. Med. Assoc. 174:234.

    CAS  Google Scholar 

  • Lee, T. C., Biglieri, E. G., Van Brunt, E. E., and Ganong, W. F. (1965). Inhibition of aldosterone secretion by passive transfer of antirenin antibodies to dogs on a low sodium diet. Proc. Soc. Exp. Biol. Med. 119:315.

    PubMed  CAS  Google Scholar 

  • Lown, B., Ganong, W. F., and Levine, S. A. (1952). The syndrome of short P-R interval, normal QRS complex and paroxysmal rapid heart action. Circulation 5:693.

    PubMed  CAS  Google Scholar 

  • Lown, B., Arons, W. L., Ganong, W. F., Vazifdar, J. P., and Levine, S. A. (1955). Adrenal steroids and auriculoventricular conduction. Am. Heart J. 50:760.

    Article  PubMed  CAS  Google Scholar 

  • Mulrow, P. J., and Ganong, W. F. (1961). The effect of hemorrhage upon aldosterone secretion in normal and hypophysectomized dogs. J. Clin. Invest. 40:579.

    Article  PubMed  CAS  Google Scholar 

  • Rabii, J., and Ganong, W. F. (1976). Responses of plasma “estradiol” and plasma LH to ovariectomy, ovariectomy plus adrenalectomy, and estrogen injection at various ages. Neuroendocrinology 20:270.

    Article  PubMed  CAS  Google Scholar 

  • Saffran, M., Schally, A. V., and Benfey, B. G. (1955). Stimulation of the release of corticotropin from the adenohypophysis by a neurohypophysial factor. Endocrinology 57:439.

    Article  PubMed  CAS  Google Scholar 

  • Share, L. (1969). Extracellular fluid volume and vasopressin secretion. In Ganong, W. F., and Martini, L. (eds.), Frontiers in Neuroendocrinology, 1969, Oxford University Press, New York, p. 183.

    Google Scholar 

  • Steenburg, R. W., and Ganong, W. F. (1955). Observations on the influence of extra-adrenal factors on circulating 17-hydroxycorticoids in the surgically stressed, adrenalectomized animal. Surgery 38:92.

    PubMed  CAS  Google Scholar 

  • Stillman, J. S., and Ganong, W. F. (1952). The Guillain-Barre syndrome: Report of a case treated with ACTH and cortisone. N. Engl. J. Med. 246:293.

    Article  PubMed  CAS  Google Scholar 

  • Tullner, W. W., and Hertz, R. (1963). Suppression of endogenous ACTH by 3-(2-amino- butyl)-indole (Monase) in the dog. In Endocrine Society Abstracts, p. 19.

    Google Scholar 

  • Winer, N., Chokshi, D. S., Yoon, M. S., and Freeman, A. D. (1969). Adrenergic receptor mediation of renin secretion. J. Clin. Endocrinol. 29:1168

    Article  CAS  Google Scholar 

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Author information

Authors and Affiliations

  1. Department of Physiology, University of California, 94143, San Francisco, California, USA

    William F. Ganong

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  1. William F. Ganong
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Editor information

Editors and Affiliations

  1. Department of Physiology, Michigan State University, East Lansing, Michigan, USA

    Joseph Meites

  2. Department of Physiology, Institute of Psychiatry, London, England

    Bernard T. Donovan

  3. Department of Physiology, The University of Texas Health Science Center at Dallas, Dallas, Texas, USA

    Samuel M. McCann

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© 1978 Plenum Press, New York

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Ganong, W.F. (1978). The Brain and the Endocrine System: A Memoir. In: Meites, J., Donovan, B.T., McCann, S.M. (eds) Pioneers in Neuroendocrinology II. Perspectives in Neuroendocrine Research, vol 2. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-4027-0_12

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  • DOI: https://doi.org/10.1007/978-1-4613-4027-0_12

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4613-4029-4

  • Online ISBN: 978-1-4613-4027-0

  • eBook Packages: Springer Book Archive

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