Summary
Sperm whale and equine myoglobin, which share 87% of their sequences, do not cross-stimulate proliferation of T lymphocytes, although they do crossreact extensively with antibodies made against either myoglobin, both for antisera and for several monoclonal antibodies. This failure to cross-stimulate T lymphocytes occurs in strain B10.S despite the fact that these mice are genetic high responders to both myoglobins.
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© 1983 Plenum Press, New York
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Berkower, I., Buckenmeyer, G.K., Gurd, F.R.N., Berzofsky, J.A. (1983). A Possible Immunodominant Domain on Myoglobin Recognized by T Lymphocytes. In: Celada, F., Schumaker, V.N., Sercarz, E.E. (eds) Protein Conformation as an Immunological Signal. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-3778-2_34
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