Skip to main content
SpringerLink
Log in

Adverse Consequences of Drinking during Pregnancy

  • Chapter
Fetal Alcohol Syndrome and Fetal Alcohol Effects

  • 242 Accesses

Abstract

Although not included in estimates of the incidence of fetal alcohol syndrome or fetal alcohol effects (see Chapter 6), increases in spontaneous abortion, stillbirth, and perinatal death have been linked to in utero alcohol exposure. The nature of this link, however, can be debated. While in utero alcohol exposure may be directly responsible for these effects, it is also conceivable that it is the “alcoholic” rather than the alcohol that is accountable. In other words, it is possible that those physiological factors that predispose a woman to become an alcoholic, and that precede her doing so, may also render her more prone to adverse pregnancy outcomes.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Log in via an institution
Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 39.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 54.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. Haddon, J. On intemperance in women, with special reference to its effects on the reproductive system. British Medical Journal, 1876, 1, 748–750.

    Article  PubMed  Google Scholar 

  2. McDaniel, W. H. The effect of alcohol upon the foetus through the blood of the mother. Maryland State Medical Journal, 1883, 10, 39–40.

    Google Scholar 

  3. Sokol, R. J., Miller, S. I., and Reed, G. Alcohol abuse during pregnancy: An epidemiological study. Alcoholism: Clinical and Experimental Research, 1980, 4, 135–145.

    Article  Google Scholar 

  4. Vitez, M., and Czeizel, E. Az iszakos—alkoholista nok termekenysege. Alkohologia, 1982, 13, 79–83.

    Google Scholar 

  5. Seidenberg, J., and Majewski, F. Zur Haufigkeit der Alkoholembryopathie in den verschiedenen Phasen der mutterlichen Alkoholkrankheit. Suchtgefahren, 1978, 24, 63–75.

    Google Scholar 

  6. Dehaene, P. H., Samaille-Villette, C. H., Samaille, P. P., Crepin, G., Walbaum, R., Deroubaix, P., and Blanc-Garin, A. P. Le syndrome d’alcoolisme foetal dans le nord de la France. Revue de l’Alcoolisme, 1977, 23, 145–158.

    Google Scholar 

  7. Bark, N. Fertility and offspring of alcoholic women: An unsuccessful search for the fetal alcohol syndrome. British Journal of Addiction, 1979, 74, 43–49.

    Article  Google Scholar 

  8. Winokur, G., and Clayton, P. Family history studies. IV. Comparison of male and female alcoholics. Quarterly Journal of Studies on Alcohol, 1968, 29, 885–891.

    PubMed  Google Scholar 

  9. Rimmer, J., Reich, T., and Winokur, G. Alcoholism. V. Diagnosis and clinical variation among alcoholics. Quarterly Journal of Studies on Alcohol, 1972, 33, 658–666.

    PubMed  Google Scholar 

  10. Schuckit, M., Pitts, F. N., Reich, T., King, L. J., and Winokur, G. Alcoholism. I. Two types of alcoholism in women. Archives of General Psychiatry, 1969, 20, 301–306.

    PubMed  Google Scholar 

  11. Kline, J., Shrout, P., Stein, Z., Susser, M., and Warburton, D. Drinking during pregnancy and spontaneous abortion. Lancet, 1980, 2, 176–180.

    Article  PubMed  Google Scholar 

  12. Harlap, S., and Shiono, P. H. Alcohol, smoking, and incidence of spontaneous abortions in the first and second trimester. Lancet, 1980, 2, 173–176.

    Article  PubMed  Google Scholar 

  13. Harlap, S., Shiono, P. H., and Ramcharan, S. Alcohol and spontaneous abortions. American Journal of Epidemiology, 1980, 110, 372.

    Google Scholar 

  14. Berkowitz, G. S. An epidemiologic study of preterm delivery. American Journal of Epidemiology, 1981, 113, 81–92.

    PubMed  Google Scholar 

  15. Moskovic, S. Effect of chronic alcohol intoxication on ovarian dysfunction. Srpski Arhiv za Celokupno Lekarstvo, 1975, 103, 751–758.

    PubMed  Google Scholar 

  16. Wall, J. H. A study of alcoholism in women. American Journal of Psychiatry, 1937, 93, 943.

    Google Scholar 

  17. Beckman, L. J. Reported effects of alcohol on the sexual feelings and behavior of women alcoholics and nonalcoholics. Journal of Studies on Alcohol, 1979, 40, 272–282.

    PubMed  Google Scholar 

  18. Belfer, M. L., Shader, R. I., Carroll, M., and Harmatz, J. S. Alcoholism in women. Archives of General Psychiatry, 1971, 25, 540–544.

    PubMed  Google Scholar 

  19. James, J. E . Symptoms of alcoholism in women: A preliminary survey of AA members. Journal of Studies on Alcohol, 1975, 36, 1564–1569.

    PubMed  Google Scholar 

  20. Lolli, G. Alcoholism in women. Connecticut Review on Alcoholism, 1953, 5, 9–11.

    Google Scholar 

  21. Podolsky, E. The woman alcoholic and premenstrual tension. Journal of the American Medical Women’s Association, 1963, 18, 816–818.

    PubMed  Google Scholar 

  22. Wilsnack, S. C. Sex role identity in female alcoholism. Journal of Abnormal Psychology, 1973, 82, 253–259.

    Article  PubMed  Google Scholar 

  23. Oisund, J. F., Fjorden, A. E., and Morlund, J. Is moderate ethanol teratogenic in the rat? Acta Pharmacologica et Toxicologia, 1978, 45, 145–155.

    Google Scholar 

  24. Tze, W. J., and Lee, M. Adverse effects of maternal alcohol consumption on pregnancy and foetal growth in rats. Nature, 1975, 257, 479–480.

    Article  PubMed  Google Scholar 

  25. Saul, G. Blockade of ovulation in the rabbit by intoxicating doses of ethyl alcohol. Anatomical Record, 1959, 133, 332.

    Google Scholar 

  26. Kieffer, J. D., and Ketchel, M. M. Blockade of ovulation in the rat by ethanol. Acta Endocrinologica, 1970, 65, 117–124.

    PubMed  Google Scholar 

  27. Cranston, E. M. Effect of tranquilizers and other agents on sexual cycle in mice. Proceedings of the Society of Experimental Biology and Medicine, 1958, 98, 320–322.

    Google Scholar 

  28. Van Thiel, D. H., Gavaler, J. S., and Lester, R. Alcohol-induced ovarian failure in the rat. Journal of Clinical Investigation, 1978, 61, 624–632.

    Article  PubMed  Google Scholar 

  29. Gomberg, E. S. Alcoholism and women: State of knowledge today. Paper presented at the National Alcoholism Forum, Milwaukee, 1975.

    Google Scholar 

  30. Lester, R., and Van Thiel, D. H. Gonadal function in chronic alcoholism. Advances in Experimental Medicine and Biology, 1977, 85A, 399–414.

    PubMed  Google Scholar 

  31. Chernoff, G. F . The fetal alcohol syndrome in mice: An animal model. Teratology, 1977, 15, 223–229.

    Article  PubMed  Google Scholar 

  32. Chernoff, G. F . The fetal alcohol syndrome in mice: Maternal variables. Teratology, 1980, 22, 71–75.

    Article  PubMed  Google Scholar 

  33. Giknis, M. L., Damjanov, I., and Rubin, E. The differential transplacental effects of ethanol in four mouse strains. Neurobehavioral Toxicology, 1980, 2, 235–237.

    Google Scholar 

  34. Kronick, J. B. Teratogenic effects of ethyl alcohol administered to pregnant mice. American Journal of Obstetrics and Gynecology, 1976, 124, 676–680.

    PubMed  Google Scholar 

  35. Randall, C. L., Taylor, W. J., and Walker, D. W. Ethanol-induced malformations in mice. Alcoholism: Clinical and Experimental Research, 1977, 1, 219–223.

    Article  Google Scholar 

  36. Randall, C. L., and Taylor, W. J. Prenatal ethanol exposure in mice: Teratogenic effects. Teratology, 1979, 19, 305–312.

    Article  PubMed  Google Scholar 

  37. Rasmussen, B. B., and Christensen, N. Teratogenic effect of maternal alcohol consumption of the mouse fetus: A histopathological study. Acta Pathologica et Microbiologica Scandinavica, Section A, Pathology, 1980, 88, 285–289.

    Google Scholar 

  38. Schwetz, B. A., Smith, F. A., and Staples, R. E. Teratogenic potential of ethanol in mice, rats, and rabbits. Teratology, 1978, 18, 385–392.

    Article  PubMed  Google Scholar 

  39. Webster, W. S., Walsh, D. A., Lipson, A. H., and McEwen, S. E. Teratogenesis after acute alcohol exposure in inbred and outbred mice. Neurobehavioral Toxicology, 1980, 2, 227–234.

    Google Scholar 

  40. Abel, E. L., and Dintcheff, B. A. Effects of prenatal alcohol exposure on growth and development in rats. Journal of Pharmacology and Experimental Therapeutics, 1978, 207, 916–921.

    PubMed  Google Scholar 

  41. Ellis, F. W., and Pick, J. R. An animal model of the fetal alcohol syndrome in beagles. Alcoholism: Clinical and Experimental Research, 1980, 4, 123–134.

    Article  Google Scholar 

  42. Altschuler, H. L., and Shippenberg, T. S. A subhuman primate model for fetal alcohol syndrome research. Neurobehavioral Toxicology and Teratology, 1981, 3, 121–126.

    Google Scholar 

  43. Gomel, V., and Carpenter, C. W. Induction of midtrimester abortion with intrauterine alcohol. Journal of Obstetrics and Gynecology, 1973, 41, 455–458.

    Google Scholar 

  44. Dubin, N. H., Blake, D. H., Parmley, T. H., Conner, E. A., Cox, R. T., and King, T. M. Intrauterine ethanol-induced termination of pregnancy in cynomolgus monkeys (Macaca fascicularis). American Journal of Obstetrics and Gynecology, 1978, 132, 789–790.

    Google Scholar 

  45. Conner, E. A., Blake, D. A., Parmley, T. H., Burnett, L. S., and King, T. M. Efficacy of various locally applied chemicals as contragestational agents in rats. Contraception, 1976, 13, 571–582.

    Article  PubMed  Google Scholar 

  46. Kaminski, M., Rumeau-Rouquette, C., and Schwartz, D. Consommation d’alcool chez les femmes enceintes et issue de la grossesse. Revue d’Epidémiologic, Médecine Sociale et Santé Publique, 1976, 24, 27–40.

    Google Scholar 

  47. Kaminski, M., Franc, M., Lebouvier, M., Du Mazaubrun, C., and Rumeau-Rouquette, C. Moderate alcohol use and pregnancy outcome. Neurobehavioral Toxicology and Teratology, 1981, 3, 173–181.

    PubMed  Google Scholar 

  48. Jones, K. L., Smith, D. W., Streissguth, S., and Myrianthopoulos, N. C. Outcome in offspring of chronic alcoholic women. Lancet, 1974, 1, 1076–1078.

    Article  PubMed  Google Scholar 

  49. Olegård, R., Sabel, K. G., Aronsson, M., Sandin, B., Johansson, P. R., Carlsson, C., Kyllerman, M., Iverson, K., and Hrbek, A. Effects on the child of alcohol abuse during pregnancy. Acta Paediatrica Scandinavica (Supplement), 1979, 275, 112–121.

    Article  Google Scholar 

  50. Lochry, E. A., Shapiro, N. R., and Riley, E. P. Growth deficits in rats exposed to alcohol in utero. Journal of Studies on Alcohol, 1980, 41, 1031–1039.

    PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Research Institute on Alcoholism, Buffalo, New York, USA

    Ernest L. Abel

Authors
  1. Ernest L. Abel
    View author publications

    You can also search for this author in PubMed Google Scholar

Rights and permissions

Reprints and permissions

Copyright information

© 1984 Ernest L. Abel

About this chapter

Cite this chapter

Abel, E.L. (1984). Adverse Consequences of Drinking during Pregnancy. In: Fetal Alcohol Syndrome and Fetal Alcohol Effects. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-2669-4_5

Download citation

  • DOI: https://doi.org/10.1007/978-1-4613-2669-4_5

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4612-9662-1

  • Online ISBN: 978-1-4613-2669-4

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics

Search

Navigation