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Immunocytology of Endocrine Tumors

  • Chapter
Immunocytochemistry in Tumor Diagnosis

Part of the book series: Developments in Oncology ((DION,volume 34))

Abstract

The introduction of immunocytologic techniques had a major impact on experimental and diagnostic histopathology. Whereas many previously applied staining procedures were nonspecific and yielded unreliable and irreproducible results, immunocytologic methods were capable of demonstrating various substances conclusively in the cells. The usefulness of immunocytology became especially apparent in the study of endocrine glands, since the products of hormone-secreting cells are antigenic and the generation of specific antisera poses no major problems. Another advantage of investigating endocrine glands is the fact that hormones are usually stored in large quantities in the cell cytoplasm, thus their localization is easier than that of other nonhormonal tissue antigens. In the last decade, numerous works have been published which dealt with immunocytologic findings related to endocrine glands. In these studies, various immunocytologic techniques were used and a deeper insight was obtained into structure-function relationships.

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  1. K. Kovacs
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  1. Michigan Cancer Foundation, USA

    Jose Russo

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Kovacs, K. (1985). Immunocytology of Endocrine Tumors. In: Russo, J. (eds) Immunocytochemistry in Tumor Diagnosis. Developments in Oncology, vol 34. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-2615-1_11

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