Summary
Isomalt is a sweetener with versatile properties due to its noncariogenicity, its practically insulin-independent metabolism and its reduced physiological caloric value compared to sugar. Isomalt is produced by hydrogenation of its precursor disaccharide isomaltulose, which is obtained from sucrose as raw material. The hydrogenation of the ketosugar isomaltulose gives a mixture of the two glucosylhexitols glucosyl-α-(1→1)-mannitol and glucosyl-α-(1→6)-sorbitol. Isomalt is now used in the formulation of toothfriendly sweets, in the production of calorie-reduced foods and in special products for diabetics. Isomalt sweetened products are sensorically not distinguishable from sucrose-based products.
Isomalt is noncariogenic, as was shown with rat caries model experiments. This was corroborated by plaque pH-telemetry in humans demonstrating the absence of any relevant intraplaque acid production from isomalt. Isomalt is not a substrate for plaquepolysaccharide synthesizing glucosyltransferases from Streptococci and was found to inhibit glucan formation of glucosyltransferase from Streptococcus mutans.
The limited digestion and absorption of isomalt in the small intestine and its symbiotic bacterial utilization in the colon are the basis for the reduced energetic utilization of isomalt compared to sugar. Most experiments for the assessment of the energetic values of polyols gave evidence, that isomalt has less than 50% of the calories of sucrose. Dietetic studies and oral glucose tolerance studies demonstrated that isomalt is a suitable sweetener for diabetics, without any adverse metabolic effects. Isomalt is due to its specific nutritional qualities a promising alternative to sucrose, with versatile properties for many food and pharmaceutical applications.
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Ziesenitz, S.C. (1996). Basic structure and metabolism of isomalt. In: Grenby, T.H. (eds) Advances in Sweeteners. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-1229-1_6
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