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AIDS in Africa: Evidence for heterosexual transmission of the human immunodeficiency virus

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Acquired Immunodeficiency Syndrome
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Abstract

Since its initial recognition in 1981, acquired immunodeficiency syndrome (AIDS) has become a global epidemic. Nearly 40,000 cases have been reported from over 85 countries on five different continents. Presently, an estimated 5–10 million people worldwide have been infected with the causative agent, referred to as the human immunodeficiency virus (HIV).1,2 From natural history studies, it can be expected that at least 10–30% of these HIV-infected individuals may develop AIDS within the next three years,3–6 resulting in a cumulative number of more than one million cases of AIDS worldwide by 1990. With the present lack of effective curative therapy or a vaccine, this disease now represents one of the most serious epidemics of the century.

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References

  1. Mahler H, Assad F: The World Health Organization’s programme on AIDS. Abstracts of the Second International Conference on AIDS, Paris, France, June 23–25, 1986, p 5.

    Google Scholar 

  2. Coffin J, Haase A, Levy JA, et al: Human immunodeficiency viruses [letter]. Science 1986; 232:697.

    Article  PubMed  CAS  Google Scholar 

  3. Curran JW, Morgan WM, Hardy AM, et al: The epidemiology of AIDS: Current status and future prospects. Science 1985; 229:1352–1357.

    Article  PubMed  CAS  Google Scholar 

  4. Melbye M: The natural history of human T lymphotropic virus-Ill infection: The cause of AIDS. Br Med J 1986; 292:5–12.

    Article  CAS  Google Scholar 

  5. Jaffe HW, Darrow WW, Echenberg DF, et al: The acquired immunodeficiency syndrome in a cohort of homosexual men: A six-year follow-up study. Ann Intern Med 1985; 103:210–214.

    PubMed  CAS  Google Scholar 

  6. Goedert JJ, Biggar RJ, Weiss SH, et al: Three-year incidence of AIDS in five cohorts of HTLV-III infected risk group members. Science 1986; 231:922–995.

    Article  Google Scholar 

  7. Clumeck N, Sonnet J, Taelman H, et al: Acquired immunodeficiency syndrome in African patients. N Engl J Med 1984; 210:492–497.

    Article  Google Scholar 

  8. Brunet JB, Ancelle R: Update: Acquired immunodeficiency syndrome—Europe. MMWR 1985; 34:583–589.

    Google Scholar 

  9. World Health Organization: Acquired immunodeficiency syndrome (AIDS): Situation in Europe as of 31 December 1985. Wkly Epidemiol Rec 1986;61:125–128.

    Google Scholar 

  10. Piot P, Quinn TC, Taelman H, et al: Acquired immunodeficiency syndrome in a heterosexual population in Zaire. Lancet 1984; 2:65–69.

    Article  PubMed  CAS  Google Scholar 

  11. Van de Perre P, Rouvroy D, Lepage P, et al: Acquired immunodeficiency syndrome in Rwanda. Lancet 1984; 2:62–65.

    Article  PubMed  Google Scholar 

  12. Quinn TC, Mann JM, Curran JW, et al: AIDS in Africa: An epidemiological paradigm. Science 1986; 234:955–963.

    Article  PubMed  CAS  Google Scholar 

  13. Kreiss JK, Koech D, Plummer FA, et al: AIDS virus infection in Nairobi prostitutes: Spread of the epidemic to East Africa. N Engl J Med 1986; 314:414–418.

    Article  PubMed  CAS  Google Scholar 

  14. Mann JM, Francis H, Quinn T, et al: Surveillance for AIDS in a Central African city: Kinshasa, Zaire. JAMA 1986; 255:3255–3259.

    Article  PubMed  CAS  Google Scholar 

  15. Melbye M, Njelesani EK, Bayley A, et al: Evidence for heterosexual transmission and clinical manifestations of human immunodeficiency virus infection and related conditions in Lusaka, Zambia. Lancet 1986; 2:1113–1115.

    Article  PubMed  CAS  Google Scholar 

  16. Aral SO, Holmes KK: Epidemiology of sexually transmitted diseases, in Holmes KK, Mardh PA, Sparling PF, et al (eds): Sexually Transmitted Diseases. New York, McGraw-Hill, pp 127–141.

    Google Scholar 

  17. Clumeck N, Robert-Guroff M, Van de Perre P, et al: Seroepidemiological studies of HTLV-III antibody prevalence among selected groups of heterosexual Africans. JAMA 1985;254:2599–2602.

    Article  PubMed  CAS  Google Scholar 

  18. Clumeck N, Van de Perre P, Carael M, et al: Heterosexual promiscuity among African patients with AIDS. N Engl J Med 1985; 313:182.

    Google Scholar 

  19. Van de Perre P, Clumeck N, Carael M, et al: Female prostitutes: A risk group for infection with human T-cell lymphotropic virus type III. Lancet 1985;2:524–527.

    PubMed  Google Scholar 

  20. Mann JM, Francis H, Davachi F, et al: HTLV-III/LAV seroprevalence in pediatric in-patients 2–14 years old in Kinshasa, Zaire. J Pediatrics 1986; 78:673–677.

    CAS  Google Scholar 

  21. Mann JM, Francis H, Quinn TC, et al: HTLV-III/LAV seroprevalence among hospital workers in Kinshasa, Zaire: Lack of association with occupational exposure. JAMA 1986;256:3099–3102.

    Article  PubMed  CAS  Google Scholar 

  22. Mann JM, Francis H, Quinn TC, et al: Role of blood transfusions in transmission of HTLV-III infection in Zaire. Am J Pub Health (in press).

    Google Scholar 

  23. Mann JM, Francis H, Davachi F, et al: Risk factors for human immunodeficiency virus seropositivity among children 1–24 months old in Kinshasa, Zaire. Lancet 1986;2:654–657.

    Article  PubMed  CAS  Google Scholar 

  24. Zuckerman AJ: AIDS and insects. Br Med J 1986; 292:1094–1095.

    Article  CAS  Google Scholar 

  25. Mann JM, Quinn TC, Francis H: Sexual practices associated with LAV/ HTLV-III seropositivity among female prostitutes in Kinshasa, Zaire. Presented at the International Conference on AIDS, Paris, France, June 23–25, 1986.

    Google Scholar 

  26. Piot P, Plummer FA, Rey M, et al: Retrospective seroepidemiology of AIDS virus infection in Nairobi populations. J Infect Dis (in press).

    Google Scholar 

  27. Mann JM, Quinn TC, Francis H, et al: Prevalence of HTLV-III/LAV in household contacts of patients with confirmed AIDS and controls in Kinshasa, Zaire. JAMA 1986;256:721–724.

    Article  PubMed  CAS  Google Scholar 

  28. Jonckheer T, Dab I, Van de Perre P, et al: Cluster of HTLV-III/LAV infection in an African family. Lancet 1985; 1:400–401.

    Article  PubMed  CAS  Google Scholar 

  29. Piot P, Mann JM: Bidirectional heterosexual transmission of human immunodeficiency virus (HIV). Presented at the International Conference on AIDS, Paris, France, June 23–25, 1986.

    Google Scholar 

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© 1989 Medical Society of the State of New York

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Quinn, T.C. (1989). AIDS in Africa: Evidence for heterosexual transmission of the human immunodeficiency virus. In: Imperato, P.J. (eds) Acquired Immunodeficiency Syndrome. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-0807-2_15

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  • DOI: https://doi.org/10.1007/978-1-4613-0807-2_15

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4612-8092-7

  • Online ISBN: 978-1-4613-0807-2

  • eBook Packages: Springer Book Archive

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