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Suppressor Cells as Possible Mediators of Immune Function after Marrow Transplantation

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Experimental Hematology Today 1979

Part of the book series: Experimental Hematology Today ((HEMATOLOGY,volume 1979))

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Abstract

The complex immunologic situation that evolves after allogeneic bone marrow transplantation is characterized by three key phenomena: graft-versus-host (GvH) reactions (17), an operational immunodeficiency lasting in man for up to 1 year post-transplantation (9,55), and finally, the development of a specific operational tolerance (4), at which a stable situation is seemingly neither perturbed by GvH or host-versus-graft (HvG) reactions. A considerable number of clinical data has been accumulated describing these situations without the mechanisms involved being fully elucidated or the possible causal interrelations between mechanisms identified.

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Authors
  1. Peter J. Tutschka
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  2. Grover M. Hutchins
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  3. George W. Santos
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Editor information

Editors and Affiliations

  1. Experimental Hematology Department Armed Forces Radiobiology Research Institute, Defense Nuclear Agency, 20014, Bethesda, Maryland, USA

    Siegmund J. Baum (Chairman) & G. David Ledney (Head) (Chairman) &  (Head)

  2. Immunology Division Experimental Hematology Department Armed Forces Radiobiology Research Institute, Defense Nuclear Agency, 20014, Bethesda, Maryland, USA

    G. David Ledney (Head) (Head)

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© 1979 Springer-Verlag New York Inc.

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Tutschka, P.J., Hutchins, G.M., Santos, G.W. (1979). Suppressor Cells as Possible Mediators of Immune Function after Marrow Transplantation. In: Baum, S.J., Ledney, G.D. (eds) Experimental Hematology Today 1979. Experimental Hematology Today, vol 1979. Springer, New York, NY. https://doi.org/10.1007/978-1-4612-6179-7_16

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  • DOI: https://doi.org/10.1007/978-1-4612-6179-7_16

  • Publisher Name: Springer, New York, NY

  • Print ISBN: 978-1-4612-6181-0

  • Online ISBN: 978-1-4612-6179-7

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