Abstract
Endothelium acts as a thromboresistant surface and limits entry of large maeromolecules such as lipoproteins and immune complexes to the underlying wall (Thorgeirsson and Robertson, 1978). Following loss of endothelium, primary hemostasis may be initiated at the surface of the artery and increased quantities of macromolecules may gain access to the wall of the artery. Although these events may initially be considered protective, eventually they may be important in the genesis of arterial disease.
The authors’ personal research cited was supported by Grants HL-01803, and HL-18828 from the National Heart, Lung and Blood Institute of the National Institutes of Health and by The Cross Foundation.
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Minick, C.R., Falcone, D.J., Hajjar, D.P. (1980). Endothelium in Experimental Atherosclerosis. In: Gotto, A.M., Smith, L.C., Allen, B. (eds) Atherosclerosis V. Springer, New York, NY. https://doi.org/10.1007/978-1-4612-6071-4_111
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DOI: https://doi.org/10.1007/978-1-4612-6071-4_111
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