Abstract
It is the nature of Alzheimer Disease (AD) that patients will suffer impaired memory, failure of the ability to reason, and loss of competency (Marson et al., 1994). Thus the question of whether or not AD patients may grant informed consent to participation in dementia research is a compelling consideration for clinical investigators as well as Institutional Review Boards (IRBs).
This is a preview of subscription content, log in via an institution to check access.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
Similar content being viewed by others
References
High DM, Whitehouse PJ, Post SG and Berg L (1994): Guidelines for addressing ethical and legal issues in Alzheimer Disease research. Alzheimer Disease and Associated Disorders 8 (Supp. 4):66.
Kapp MB (1994): Proxy decision making in Alzheimer Disease research: durable powers of attorney, guardianship, and other alternatives. Alzheimer Disease and Associated Disorders 8 (Supp. 4):28.
Marson DC, Ingram KK, Cody HA and Harrell LE (1995): Assessing the competency of patients with Alzheimer’s Disease under different legal standards: a prototype instrument. Arch Neurol 52:949.
Marson DC, Schmitt FA, Ingram KK and Harrell LE (1994): Determining the competency of Alzheimer patients to consent to treatment and research. Alzheimer Disease and Associated Disorders 8 (Supp. 4):5.
Moore DL (1994): An IRB member’s perspective on access to innovative therapy. Albany L Rev 57:559.
Popp AJ and Moore DL (1994): Institutional review board evaluation of neuroscience protocols involving human subjects. Surg Neurol 41:162.
Resau LS (1995): Obtaining informed consent in Alzheimer’s research. J Neuroscience Nursing 27(1):57.
Sachs GA (1994): Advance consent for dementia research. Alzheimer Disease and Associated Disorders 8 (Supp. 4):19.
Sachs GA, Stocking CB, Stern R, Cox DM, Hougham G and Sachs RS (1994): Ethical aspects of dementia research: informed consent and proxy consent. Clinical Research 42:403.
Author information
Authors and Affiliations
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 1997 Birkhäuser Boston
About this chapter
Cite this chapter
LeBlang, T.R., Kirchner, J.L. (1997). Informed Consent and Alzheimer Disease Research: Institutional Review Board Policies and Practices. In: Becker, R.E., Giacobini, E., Barton, J.M., Brown, M. (eds) Alzheimer Disease. Advances in Alzheimer Disease Therapy. Birkhäuser Boston. https://doi.org/10.1007/978-1-4612-4116-4_81
Download citation
DOI: https://doi.org/10.1007/978-1-4612-4116-4_81
Publisher Name: Birkhäuser Boston
Print ISBN: 978-1-4612-8660-8
Online ISBN: 978-1-4612-4116-4
eBook Packages: Springer Book Archive