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Preclinical and Clinical Progress with Huperzine A: A Novel Acetylcholinesterase Inhibitor

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Alzheimer Disease

Part of the book series: Advances in Alzheimer Disease Therapy ((AADT))

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Abstract

Alzheimer’s disease (AD) is a progressive neurodegenerative disease that attacks the brain and results in impaired memory, thinking and behaviour in the elderly. This disease is pathologically characterized by the degeneration of the basal forebrain cholinergic system and the deposit of amyloid plaques in the brain (Whitehouse et al., 1982; Selkoe, 1991). It has become the fourth leading cause of death in developed nations. In the USA, the costs related to AD exceed those of related to cancer and heart disease. Yet, at present, there is no effective treatment available for this disorder.

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© 1997 Birkhäuser Boston

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Han, Y., Tang, X. (1997). Preclinical and Clinical Progress with Huperzine A: A Novel Acetylcholinesterase Inhibitor. In: Becker, R.E., Giacobini, E., Barton, J.M., Brown, M. (eds) Alzheimer Disease. Advances in Alzheimer Disease Therapy. Birkhäuser Boston. https://doi.org/10.1007/978-1-4612-4116-4_36

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  • DOI: https://doi.org/10.1007/978-1-4612-4116-4_36

  • Publisher Name: Birkhäuser Boston

  • Print ISBN: 978-1-4612-8660-8

  • Online ISBN: 978-1-4612-4116-4

  • eBook Packages: Springer Book Archive

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