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Surgical Treatment of PVR

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Proliferative Vitreoretinopathy (PVR)

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Abstract

Proliferative vitreoretinopathy (PVR) is the most common cause of failure in retinal reattachment surgery.1 The basic pathologic process is growth and contracture of cellular membranes on both sides of the retina and on the posterior vitreous surface.2–5 This results in centripetal and postero-anterior traction on the peripheral retina from contracture in the region of the vitreous base. Fixed folds of the posterior retina occur due to contraction of epiretinal membranes (Fig. 1).

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References

  1. The Retina Society Terminology Committee. The classification of retinal detachment with proliferative vitreoretinopathy. Ophthalmology 1983;90:121–125.

    Google Scholar 

  2. Machemer R. Pathogenesis and classification of massive periretinal proliferation. Br J Ophthalmol 1978; 62:737–747.

    Article  PubMed  CAS  Google Scholar 

  3. Machemer R, Laqua H. Pigment epithelial proliferation and retinal detachment (massive periretinal proliferation). Am J Ophthalmol 1975;80:1–23.

    PubMed  CAS  Google Scholar 

  4. Laqua H, Machemer R. Glial cell proliferation and retinal detachment (massive periretinal proliferation). Am J Ophthalmol 1975; 80:602–618.

    PubMed  CAS  Google Scholar 

  5. Laqua H, Machemer R. Clinical-pathological correlation in massive periretinal proliferation. Am J Ophthalmol 1975; 80:913–929.

    PubMed  CAS  Google Scholar 

  6. Michels RG. Surgery of retinal detachment with proliferative vitreoretinopathy. Retina 1984;4:63–83.

    Article  PubMed  CAS  Google Scholar 

  7. Ando F. Intraocular hypertension resulting from pupillary block by silicone oil. Am J Ophthalmol 1985; 99:87–88.

    PubMed  CAS  Google Scholar 

  8. Campochiaro PA, Jerdan JAN, Glaser BM. Serum contains chemoattractants for human retinal pigment epithelial cells. Arch Ophthalmol 1984; 102:1830–1833.

    PubMed  CAS  Google Scholar 

  9. Campochiaro PA, Glaser BM. Platelet-derived growth factor is chemotactic for human retinal pigment epithelial cells. Arch Ophthalmol 1985; 103:576–579.

    PubMed  CAS  Google Scholar 

  10. Grizzard WS, Hilton GF: Scleral buckling for retinal detachments complicated by periretinal proliferation. Arch Ophthalmol 1982; 100:419–422.

    PubMed  CAS  Google Scholar 

  11. Yoshida A, Ho PC, Schepens CL, et al. Severe proliferation vitreoretinopathy and retinal detachment. II. Surgical results with scleral buckling. Ophthalmology 1984; 1538–1543.

    Google Scholar 

  12. Schepens CL. Clinical and research aspects of subtotal open-sky vitrectomy. Am J Ophthalmol 1981; 91:143–171.

    PubMed  CAS  Google Scholar 

  13. Sternberg P, Machemer R. Results of conventional vitreous surgery for proliferative vitreoretinopathy. Am J Ophthalmol 1985; 100:141–146.

    PubMed  Google Scholar 

  14. Chang S, Coleman DJ, Lincoff H, et al. Perfluoropropane gas in the management of proliferative vitreoretinopathy. Am J Ophthalmol 1984;98:180–188.

    PubMed  CAS  Google Scholar 

  15. Jalkh AE, Avila MP, Schepens CL, et al. Surgical treatments of proliferative vitreoretinopathy. Arch Ophthalmol 1984; 102:1135–1139.

    PubMed  CAS  Google Scholar 

  16. Blumenkranz M, Hernandez E, Ophir A, et al. 5-fluorouracil: New applications in complicated retinal detachment for an established antimetabolite. Ophthalmology 1984; 91:122–130.

    PubMed  CAS  Google Scholar 

  17. de Bustros S, Michels RG. Surgical treatment of retinal detachments complicated by proliferative vitreoretinopathy. Am J Ophthalmol 1984; 98:694–699.

    PubMed  Google Scholar 

  18. Parke DW II, Aaberg TM. Intraocular argon laser photocoagulation in the management of severe proliferative vitreoretinopathy. Am J Ophthalmol 1984; 97:434–443.

    PubMed  Google Scholar 

  19. Ho PC, McMeel JW. Retinal detachment with proliferative vitreoretinopathy. Br J Ophthalmol 1985; 69:584–587.

    Article  PubMed  CAS  Google Scholar 

  20. Grey RHB, Leaver PK. Silicone oil in the treatment of massive preretinal retraction. I. Results in 105 eyes. Br J Ophthalmol 1979; 63:355–360.

    Article  PubMed  CAS  Google Scholar 

  21. Gonvers M. Temporary use of intraocular silicone oil; the treatment of detachment with massive periretinal proliferation; preliminary report. Ophthalmologica 1982; 184:210–218.

    Article  PubMed  CAS  Google Scholar 

  22. Lean JS, Leaver PK, Cooling RJ, McLeod D. Management of complex retinal detachments by vitrectomy and fluid/silicone exchange. Trans Ophthalmol Soc UK 1982; 102:203–205.

    PubMed  Google Scholar 

  23. Cox MS, Trese MT, Murphy PL. Silicone oil for advanced proliferative vitreoretinopathy. Ophthalmology 1986; 93:646–650.

    PubMed  CAS  Google Scholar 

  24. Sell CH, McCuen MW, Landers MB, et al. Long-term results of successful vitrectomy with silicone oil for advanced proliferative vitreoretinopathy. Am J Ophthalmol 1987; 103:24–28.

    PubMed  CAS  Google Scholar 

  25. Yeo JH, Glaser BM, Michels RG. Silicone oil in the treatment of complicated retinal detachments. Ophthalmology 1987; 94:1109–1113.

    PubMed  CAS  Google Scholar 

  26. Tano Y Sugita G, Abrams G, et al. Inhibition of intraocular proliferations with intravitreal corticosteroids. Am J Ophthalmol 1980; 89:131–136.

    PubMed  CAS  Google Scholar 

  27. Tano Y, Chandler D, Machemer R. Treatment of intraocular proliferation with intravitreal injection of trimcinolone acetonide. Am J Ophthalmol 1980; 90:810–816.

    PubMed  CAS  Google Scholar 

  28. Blumenkranz MS, Ophir A, Clafin AJ, et al. Fluorouracil for the treatment of massive periretinal proliferation. Am J Ophthalmol 1982; 94:458–467.

    PubMed  CAS  Google Scholar 

  29. Stern WH, Lewis GP, Erickson PA, et al. Fluorouracil therapy for proliferative vitreoretinopathy after vitrectomy. Am J Ophthalmol 1983; 96:33–42.

    PubMed  CAS  Google Scholar 

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Authors
  1. Anne M. Hanneken
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  2. Ronald G. Michels
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Editor information

Editors and Affiliations

  1. Harvard Medical School, Boston, Massachusetts, 02114, USA

    H. MacKenzie Freeman MD (Associate Clinical Professor of Ophthalmology, Surgeon in Ophthalmology, Senior Clinical Scientist) & Felipe I. Tolentino MD (Associate Clinical Professor of Ophthalmology, Associate Surgeon in Ophthalmology, Program Director) (Associate Clinical Professor of Ophthalmology, Surgeon in Ophthalmology, Senior Clinical Scientist) &  (Associate Clinical Professor of Ophthalmology, Associate Surgeon in Ophthalmology, Program Director)

  2. Massachusetts Eye and Ear Infirmary, Boston, Massachusetts, 02114, USA

    H. MacKenzie Freeman MD (Associate Clinical Professor of Ophthalmology, Surgeon in Ophthalmology, Senior Clinical Scientist) & Felipe I. Tolentino MD (Associate Clinical Professor of Ophthalmology, Associate Surgeon in Ophthalmology, Program Director) (Associate Clinical Professor of Ophthalmology, Surgeon in Ophthalmology, Senior Clinical Scientist) &  (Associate Clinical Professor of Ophthalmology, Associate Surgeon in Ophthalmology, Program Director)

  3. Ophthalmic Microsurgery Laboratory, Eye Research Institute of Retina Foundation, Boston, Massachusetts, 02114, USA

    H. MacKenzie Freeman MD (Associate Clinical Professor of Ophthalmology, Surgeon in Ophthalmology, Senior Clinical Scientist) & Felipe I. Tolentino MD (Associate Clinical Professor of Ophthalmology, Associate Surgeon in Ophthalmology, Program Director) (Associate Clinical Professor of Ophthalmology, Surgeon in Ophthalmology, Senior Clinical Scientist) &  (Associate Clinical Professor of Ophthalmology, Associate Surgeon in Ophthalmology, Program Director)

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© 1988 Springer-Verlag New York Inc.

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Hanneken, A.M., Michels, R.G. (1988). Surgical Treatment of PVR. In: Freeman, H.M., Tolentino, F.I. (eds) Proliferative Vitreoretinopathy (PVR). Springer, New York, NY. https://doi.org/10.1007/978-1-4612-3910-9_7

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  • DOI: https://doi.org/10.1007/978-1-4612-3910-9_7

  • Publisher Name: Springer, New York, NY

  • Print ISBN: 978-1-4612-8398-0

  • Online ISBN: 978-1-4612-3910-9

  • eBook Packages: Springer Book Archive

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