Use of Magnetic Source Imaging in Surgical Planning for Epilepsy Patients who have Undergone Prior Resection

Abstract

While surgical intervention often substantially reduces seizure activity, a number of cases arise in which the seizure activity following resection is either not reduced as much as desirable or is initially reduced but increases in frequency and severity over time. In these cases, further surgery may be indicated. A quick, non-invasive means to assess the location of remaining epileptogenic activity would be a valuable tool for this purpose. A key issue is whether the continuing seizures originate from zones adjacent to prior surgery, or whether they represent multifocal regions or areas not adjacent to prior surgery which were previously undetected which had developed since the surgery.