A Diagnosis Not to Forget

Abstract

Transient global amnesia (TGA) is characterised by the sudden onset of anterograde amnesia with perseveration and repetitive questioning. There are several reported triggers for the attacks, including extremes of temperature, immersion in cold water, travel to unfamiliar places, emotional or painful events, a Valsalva manoeuvre, and exercise, including coitus. Occasionally, detailed neuropsychological testing may show mild long-term impairment of memory but whether such findings are related to the episode of TGA is uncertain. It is a condition often encountered in the TIA clinic and can provide a diagnostic challenge, especially in older patients who have additional risk factors.