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Scientific Visualization pp 79–92Cite as

Fuzzy Fibers: Uncertainty in dMRI Tractography

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Part of the book series: Mathematics and Visualization ((MATHVISUAL))

Abstract

Fiber tracking based on diffusion weighted Magnetic Resonance Imaging (dMRI) allows for noninvasive reconstruction of fiber bundles in the human brain. In this chapter, we discuss sources of error and uncertainty in this technique, and review strategies that afford a more reliable interpretation of the results. This includes methods for computing and rendering probabilistic tractograms, which estimate precision in the face of measurement noise and artifacts. However, we also address aspects that have received less attention so far, such as model selection, partial voluming, and the impact of parameters, both in preprocessing and in fiber tracking itself. We conclude by giving impulses for future research.

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Authors and Affiliations

  1. University of Bonn, Bonn, Germany

    Thomas Schultz

  2. MPI for Intelligent Systems, University of Bonn, Tübingen, Germany

    Thomas Schultz

  3. TU Delft, Delft, Netherlands

    Anna Vilanova

  4. TU Eindhoven, Eindhoven, Netherlands

    Anna Vilanova & Ralph Brecheisen

  5. University of Chicago, Chicago, USA

    Gordon Kindlmann

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  1. Thomas Schultz
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  2. Anna Vilanova
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  3. Ralph Brecheisen
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  4. Gordon Kindlmann
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Correspondence to Thomas Schultz .

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Editors and Affiliations

  1. School of Computing Scientific Computing and Imaging Institu, University of Utah, Salt Lake City, Utah, USA

    Charles D. Hansen

  2. e-Research Centre, University of Oxford, Oxford, United Kingdom

    Min Chen

  3. School of Computing Scientific Computing and Imaging Institu, University of Utah, Salt Lake City, Utah, USA

    Christopher R. Johnson

  4. Department of Computer Science, Stony Brook University, New York, New York, USA

    Arie E. Kaufman

  5. Fachbereich Informatik, Technische Universität Kaiserslautern, Kaiserslautern, Germany

    Hans Hagen

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Schultz, T., Vilanova, A., Brecheisen, R., Kindlmann, G. (2014). Fuzzy Fibers: Uncertainty in dMRI Tractography. In: Hansen, C., Chen, M., Johnson, C., Kaufman, A., Hagen, H. (eds) Scientific Visualization. Mathematics and Visualization. Springer, London. https://doi.org/10.1007/978-1-4471-6497-5_8

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