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Merkel Cell Carcinoma

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Mohs Micrographic Surgery

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Abstract

Merkel cell carcinoma (MCC) is a rare, aggressive tumor of neuroendocrine ­derivation mostly seen in elderly and immunosuppressed individuals. MCC has a propensity for local recurrence and regional and distant metastases. Because of the rarity of MCC, no evidenced-based unified treatment algorithm exists. Surgery is the mainstay of treatment for localized MCC. Mohs micrographic surgery (MMS) may be a tissue-sparing alternative to wide local excision. Radiation of the primary tumor site and/or regional lymph node basin may favorably improve recurrence rates. Chemotherapy is an option for inoperable or widespread disease. Prognosis is generally poor, especially if regional and distant metastases are present.

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Author information

Authors and Affiliations

  1. Department of Dermatology, Geisinger Medical Center, Danville, PA, USA

    Stephanie A. Diamantis

  2. Department of Dermatologic Surgery, Geisinger Health System, Danville, PA, USA

    Victor J. Marks

Authors
  1. Stephanie A. Diamantis
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  2. Victor J. Marks
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Correspondence to Stephanie A. Diamantis .

Editor information

Editors and Affiliations

  1. Miller School of Medicine, Dept. Dermatology, University of Miami, NW. 10th Ave. 1600, Miami, 33136, Florida, USA

    Keyvan Nouri

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© 2012 Springer-Verlag London Limited

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Diamantis, S.A., Marks, V.J. (2012). Merkel Cell Carcinoma. In: Nouri, K. (eds) Mohs Micrographic Surgery. Springer, London. https://doi.org/10.1007/978-1-4471-2152-7_24

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  • DOI: https://doi.org/10.1007/978-1-4471-2152-7_24

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  • Publisher Name: Springer, London

  • Print ISBN: 978-1-4471-2151-0

  • Online ISBN: 978-1-4471-2152-7

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