Abstract
This benign bone tumor, arising from the medullary fat tissue is, on the whole, a very rare bone lesion, but it does occur in children. Lipoma is an absolutely benign lesion that develops slowly in the medullary cavity of a bone, with proliferation of the marrow fat tissue and usually inducing a clearly demarcated “bone cyst”. No clinical symptoms result, and mostly the lesion is detected by chance.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
Literature
Adkins KF, Marinez MG, Hartley MW. Ultrastructure of giant-cell lesions. A peripheral giant-cell reparative granuloma. Oral Surg 1969; 28: 713–23
Adler CP. Granulomatöse Erkrankungen im Knochen. Verh Dtsch Ges Pathol 1980; 64: 359–65
Adler CP, Härle F. Zur Differentialdiagnose osteofibröser Kiefererkrankungen. Verh Dtsch Ges Pathol 1974; 58: 308–14
Adler CP, Schaefer HE. Histiocytosis X of the left femur — proximal segment. Case report. Skeletal Radiol 1988; 17: 531–5
Augerau B, Thuilleux G, Moinet Ph. Eosinophil granuloma of bones. Report of 15 cases including 10 survivals with an average follow up of 4 years. J Chir (Paris) 1977; 113: 159–70
Austin LT Jr, Dahlin DC, Royer EQ. Giant-cell reparative granuloma and related conditions affecting the jawbones. Oral Surg 1959; 12: 1285–95
Bauer FHC, Mirra JM, Urist MR. Bone induction by Ewing’s sarcoma. Arch Pathol Lab Med 1981; 105: 322–4
Beckstead JH, Wood GS, Turner RR. Histiocytosis X cells and Langerhans cells: enzyme histochemical and immunologic similarities. Hum Pathol 1984; 15: 826–33
Bergholz M, Schauer A, Poppe H. Diagnostic and differential diagnostic aspects in histiocytosis X diseases. Pathol Res Pract 1979; 166: 59–71
Gatto M, Stevens J. Liposarcoma of bone. J Pathol Bacteriol 1963; 86: 248–53
Cheyne C. Histiocytosis X. J Bone Jt Surg 1971;B-53:366–82
Child PL. Lipoma of the os calcis. Report of a case. Am J Clin Pathol 1955; 25: 1050–2
Cuvelier A, L’Her P, Schill H, Jancovici R, Bassoulet J, Vauterin G, et al. Ewing’s sarcoma and peripheral neuroectodermal tumors. Report of a case with laterothoracic localization. Rev Pneumol Clin 1990; 46: 116–22
Dawson EK. Liposarcoma of bone. J Pathol Bacteriol 1955; 70: 513–20
Dickman PS, Liotta LA, Triche TJ. Ewing’s sarcoma: characterization in established culture and evidence of its histogenesis. Lab Invest 1982; 47: 375–82
Estes DN, Magill HL, Thompson EI, Hayes FA. Primary Ewing sarcoma: follow-up with Ga-67 scintigraphy. Radiology 1990; 177: 449–53
Evans JE. Ewing’s tumour: uncommon presentation of an uncommon tumour. Med J Aust 1977; 1: 590–1
Favara BE, McCarthy RC, Mierau GW. Histiocytosis X. Hum Pathol 1983; 14: 663–76
Fiche M, Le-Tourneau A, Audouin J, Touzard RC, Diebold J. A case of primary osseous malignant immunoblastic B-cell lymphoma with intracytoplasmic mu lambda immunglobulin inclusions. Histopathology 1990; 16: 167–72
Gedigk P, Bechtelsheimer H, Koch H. Das eosinophile Granulom des Knochens. Med Welt 1964; 50: 2699–701
Goldman RL. Primary liposarcoma of one. Report of a case. Am J Clin Pathol 1964; 42: 503–8
Hermichen HG, Wentzensen A. Stabile Osteosynthese nach Beckenschaufelresektion bei intraossärem Ewing-Sarkom. Aktuel Traumatol 1988; 18: 204–8
Hustu HO, Pinkel D. Lymphoma, Hodgkin’s disease and leukemia in bone. Clin Orthop 1967; 52: 83–93
Ide F, Iwase T, Saito I, Umemura S, Nakajima T. Immunohistochemical and ultrastructural analysis of the proliferating cells in histiocytosis X. Cancer 1984; 53: 917–21
Ivins JC, Dahlin DC. Malignant lymphoma (reticulum cell sarcoma) of bone. Proc Mayo Clin 1963; 38: 375–85
Jaffe HL. Giant-cell reparative granuloma, traumatic bone cyst, and fibrous (fibro-osseous) dysplasia of the jawbones. Oral Surg 1953; 6: 159–75
Jaffe R, Santamaria M, Yunis EJ, Tannery NH, Agostini RM, Medina J, et al. The neuroectodermal tumour of bone. Am J Surg Pathol 1984; 8: 885–98
Kadin ME, Bensch KG. On the origin of Ewing’s tumor. Cancer 1971; 27: 257–73
Kauffman SL, Stout AP. Lipoblastic tumors of children. Cancer (Phil) 1959; 12: 912–25
Kissane JM, Askin FB, Foulkes M, Stratton LB, Shirley SF. Ewing’s sarcoma study. Hum Pathol 1983; 14: 773–9
Kozlowski K, Barylak A, Campbell J, Hoeffel JD, Beluffi G, Masel J, et al. Primary sacral bone tumours in children (report of 16 cases with a short literature review). Austr Radiol 1990; 34: 142–9
Ladanyl M, Heinemann FS, Huvos AG, Rao PH, Chen QG, Jhanwar SC. Neural differentiation in small round cell tumors of bone and soft tissue with the translocation t (11;22) (q24;q12): an immunohistochemical study of 11 cases. Hum Pathol 1990; 21: 1245–51
Landing BJ. Lymphohistiocytosis in childhood. Pathologic comparison with fatal Letterer—Siwe disease (disseminated visceral histiocytosis X). Perspect Pediatr Pathol 1987; 9: 48–74
Lichtenstein L. Histiocytosis X, integration of eosinophilic granuloma of bone, Letterer-Siwe disease and SchüllerChristian disease as related manifestations of a single nosologic entity. Arch Pathol 1953; 50: 84–102
Lichtenstein L, Jaffe HL. Eosinophilic granuloma of bone with report of case. Am J Pathol 1940; 16: 595–604
Llombart-Bosch A, Carda C, Peydro-Olaya A, Noguera R, Perez-Bacete M, Pellin A, et al. Soft tissue Ewing’s sarcoma. Characterization in established cultures and xenografts with evidence of a neuroectodermic phenotype. Cancer 1990; 66: 2589–601
Macintosh DJ, Price CHG, Jeffree GM. Malignant lymphoma (reticulosarcoma) in bone. Clin Oncol 1977; 3: 287–300
Matejovsky Z, Povysil C. Das Ewing-Sarkom. Neue klinisch-pathologische Aspekte. Zentralbl Allg Pathol 1986; 132: 11–24
Mickelson MR, Bonfiglio M. Eosinophilic granuloma and its variations. Orthop Clin N Am 1977; 8: 933–45
Moorefield WG Jr, Urbaniak JR, Gonzalvo AAA. Intramedullary lipoma of the distal femur. South Med J (Bgham Ala) 1976; 69: 1210–11
Moser RP, Davis MJ, Gilkey FW, Kransdorf MJ, Rosado de Christenson ML, Kumar R, et al. Primary Ewing’s sarcoma of rib. Radiographics 1990; 10: 899–914
Nezelof C. Histiocytosis X: A histological and histogenetic study. In: Rosenberg HS, Bolande RP, eds. Perspectives in pediatric pathology, vol 5. New York: Masson, 1979: 153–78
Nezelof C, Barbey S. Histiocytosis. Nosology and pathology. Pediatr Pathol 1985; 3: 1–41
Nezelof C, Frileux-Herbet F, Cronier-Sachot J. Disseminated histiocytosis X: analysis of prognostic factors based on a retrospective study of 50 cases. Cancer 1979; 44: 1824–38
Perez-Atayde AR, Grier H, Weinstein H, Delorey M, Leslie N, Vawter G. Neuroectodermal differentiation in bone tumors presenting as Ewing’s sarcoma. Proc Int Soc Pediatr Oncol 1985; 17: 61
Rainier SS, Hollabaugh E. Histiocytic symdromes. Dermatol Clin 1989; 7: 491–503
Rehak L, Blasko I, Huraj E Jr, Galbavy S. Problems in the diagnosis of Ewing’s sarcoma. Acta Chir Orthop Traumatol Cech 1989; 56: 529–37
Retz LD. Primary liposarcoma of bone. Report of a case and review of the literature. J Bone Jt Surgery 1961; A43: 123–9
Risdall RJ, Dehner LP, Duray P, Kobrinsky N, Robison L, Nesbit ME Jr. Histiocytosis X (Langerhans’ cell histiocytosis). Prognostic role of histiopathology. Arch Pathol Lab Med 1983; 107: 59–63
Ruco LP, Remotti D, Monardo F, Uccini S, Cristiani ML, Modesti A, et, al. Letterer-Siwe disease: immunohistochemical evidence for a proliferative disorder involving immature cells of Langerhans’ lineage. Virchows Arch A Pathol Anat 1988; 413: 239–247
Rüschoff J, Rieger CHL, Gabel F-J, Thomas C. Histiocytosis X. Med Welt (Stuttg) 1988; 39: 886–9
Salzer M, Salzer-Kuntschik M. Zur Frage der sogenannten zentralen Knochenlipome. Beitr Pathol Anat 1965; 132: 365–75
Scarpa S, D’Orazi G, Modesti M, Modesti A. Ewing’s sarcoma lines synthesize laminin and fibronectin. Virchows Arch [A] 1987; 410: 375–81
Schajowicz F. Eosinophilic granuloma of bone and its relationship to Hand-Schuller-Christian and LettererSiwe syndromes. J Bone Jt Surg 1973;B-55:545–65
Schwartz A, Shuster M, Becker SM. Liposarcoma of bone: report of a case and review of the literature. J Bone Jt Surg 1970; A52: 171–7
Short JH. Malignant lymphoma (reticulum cell sarcoma) of bone. Radiography 1977; 43: 139–43
Smith WE, Fienberg R. Intraosseous lipoma of bone. Cancer (Phil) 1957; 10: 1151–2
Sneath RS, Carter SR, Grimer RJ. Ewing’s sarcoma. Fifteen years of experience. Chir Organi Mov 1990; 75: 260–1
Spritz RA. The familial histiocytoses. Pediatr Pathol 1985; 3: 43–57
Telles NC, Rabson AS, Pomeroy TC. Ewing’s sarcoma: an autopsy study. Cancer (Phil) 1978; 41: 2321–9
Toni A, Sudanese A, Ciaroni D, Picci P, Bacci G, Neff JR, et al. The role of surgery in the local treatment of Ewing’s sarcoma of the extremities. Chir Organi Mov 1990; 75: 262–4
Triche TJ. Round cell tumors in childhood: the application of newer techniques to the differential diagnosis. In: Rosenberg HS, Bernstein J, eds. Perspectives in pediatric pathology. New York: Masson, 1982: 279–322
Triche TJ, Askin FB. Neuroblastoma and the differential diagnosis of small-, round-blue-cell tumors. Hum Pathol 1983; 14: 569–595
Triche TJ, Tsokos M, Miser JS Reynolds CP, Israel MA, Donner L. Peripheral neuroepithelioma. A bone or soft tissue tumor resembling Ewing’s sarcoma and distinct from neuroblastoma. Proc Int Soc Pediatr Oncol 1985; 17: 47
Uehlinger E, Botsztejn C, Schinz HR. Ewingsarkom und Knochenretikulosarkom. Klinik, Diagnose und Differentialdiagnose. Oncologia (Basel) 1948; 1: 193–245
Willis RA. Metastatic neuroblastoma in bone presenting the Ewing syndrome, with a discussion of “Ewing’s sarcoma”. Am J Pathol 1940; 16: 317–31
Author information
Authors and Affiliations
Rights and permissions
Copyright information
© 1993 Springer-Verlag London Limited
About this chapter
Cite this chapter
Adler, CP., Kozlowski, K. (1993). Tumors of Marrow Origin. In: Primary Bone Tumors and Tumorous Conditions in Children. Springer, London. https://doi.org/10.1007/978-1-4471-1951-7_6
Download citation
DOI: https://doi.org/10.1007/978-1-4471-1951-7_6
Publisher Name: Springer, London
Print ISBN: 978-1-4471-1953-1
Online ISBN: 978-1-4471-1951-7
eBook Packages: Springer Book Archive