Abstract
In vitro tests are very powerful methods to assess the carcinogenic effects of different substances and to study the initial phases of tumor development. A CA model of the formation of transformation foci in cell cultures which are exposed to a carcinogen is presented here, based on known facts about carcinogenesis and about reasonable assumptions, which gives rise to a cell growth dynamics similar to the one experimentally observed. The model can be used to test formal hypotheses about different interfering phenomena and about their relative strength.
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© 2001 Springer-Verlag London Limited
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Serra, R., Villani, M., Colacci, A. (2001). A cellular automata model for the simulation of in vitro carcinogenesis tests. In: Bandini, S., Worsch, T. (eds) Theory and Practical Issues on Cellular Automata. Springer, London. https://doi.org/10.1007/978-1-4471-0709-5_16
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DOI: https://doi.org/10.1007/978-1-4471-0709-5_16
Publisher Name: Springer, London
Print ISBN: 978-1-85233-388-1
Online ISBN: 978-1-4471-0709-5
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