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Enteropathies Associated with Chronic Diarrhea and Malabsorption of Infancy and Childhood

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Pathology of Pediatric Gastrointestinal and Liver Disease

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Abstract

The aims of this chapter are to review the enteropathies that cause chronic, severe diarrhea and malabsorption in childhood, explore their pathophysiology, and illustrate their appearance on intestinal specimens. Endoscopic gastrointestinal biopsies constitute an important portion of the pathologist’s workload, accounting for nearly one-third of specimens accessioned yearly by the pathology department at The Children’s Hospital of Philadelphia. The widespread use of endoscopy and gastrointestinal biopsies in current clinical practice presents the pathologist with a diversity of intestinal mucosal appearances corresponding to disease states of variable clinical severity, requiring close collaboration between clinician and pathologist for optimal interpretation.

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  1. Pierre Russo
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Editors and Affiliations

  1. Department of Pathology and Laboratory Medicine, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, 19104, USA

    Pierre Russo MD (Associate Professor, Director) & Eduardo D. Ruchelli MD (Assistant Professor) (Associate Professor, Director) &  (Assistant Professor)

  2. Division of Anatomic Pathology, The Children’s Hospital of Philadelphia, Philadelphia, PA, 19104, USA

    Pierre Russo MD (Associate Professor, Director) (Associate Professor, Director)

  3. Staff Pathologist, The Children’s Hospital of Philadelphia, Philadelphia, PA, 19104, USA

    Eduardo D. Ruchelli MD (Assistant Professor) (Assistant Professor)

  4. Department of Pediatrics, University of Pennsylvania School of Medicine, Philadelphia, PA, 19104, USA

    David A. Piccoli MD (Professor, Division Chief) (Professor, Division Chief)

  5. Gastroenterology and Nutrition, The Children’s Hospital of Philadelphia, Philadelphia, PA, 19104, USA

    David A. Piccoli MD (Professor, Division Chief) (Professor, Division Chief)

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Russo, P. (2004). Enteropathies Associated with Chronic Diarrhea and Malabsorption of Infancy and Childhood. In: Russo, P., Ruchelli, E.D., Piccoli, D.A. (eds) Pathology of Pediatric Gastrointestinal and Liver Disease. Springer, New York, NY. https://doi.org/10.1007/978-1-4419-9066-2_4

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  • DOI: https://doi.org/10.1007/978-1-4419-9066-2_4

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