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Liver Development

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Molecular Pathology of Liver Diseases

Part of the book series: Molecular Pathology Library ((MPLB,volume 5))

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Abstract

About 5% of the body mass of mammals is made up by the liver, our largest internal organ. Absence of the liver is not compatible with life, due to the multiple essential metabolic functions of the organ. In addition, multiple diseases are caused wholly or in part by impaired liver function. Examples of the impressive functional diversity of the liver, which are discussed in detail elsewhere in this volume, are the secretion of serum components and clotting factors, the regulation of glucose, protein and lipid metabolism, and the detoxification of xenobiotics, drugs, and other chemicals.

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  1. Department of Genetics, University of Pennsylvania School of Medicine, Philadelphia, PA, USA

    Klaus H. Kaestner

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Correspondence to Klaus H. Kaestner .

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  1. School of Medicine, Dept. Pathology, University of Pittsburgh, 200 Lothrop Street, S421-BST, Pittsburgh, 15261, Pennsylvania, USA

    Satdarshan P. S. Monga

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Kaestner, K.H. (2011). Liver Development. In: Monga, S. (eds) Molecular Pathology of Liver Diseases. Molecular Pathology Library, vol 5. Springer, Boston, MA. https://doi.org/10.1007/978-1-4419-7107-4_13

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  • DOI: https://doi.org/10.1007/978-1-4419-7107-4_13

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