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Traumatic Injuries

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Biomaterials for Clinical Applications

Abstract

Road traffic accidents are the ninth leading killer worldwide. In 2004, road traffic accidents were responsible for 1.3 million deaths or 2.2% of all deaths globally and 3.3% of all years of life lost (World Health Organization 2008). Traumatic injuries resulting from traffic accidents are extremely common. Each year, 24.3 million individuals worldwide suffer injuries severe enough to require medical attention, as a result of road traffic accidents (World Health Organization 2008). Other catastrophes add further to the annual toll of traumatic injuries worldwide. For instance, 37.3 million individuals around the globe experience traumatic injuries from falls, 10.9 million individuals suffer injuries from fires, and 17.2 million individuals experience injuries from violence every year. Despite refinements in suturing and stapling techniques for tissue reattachment and wound closure , surgeons continue to struggle with difficult tissue repairs. Reliable closure of tissues and organs remains one of the great unsolved challenges of clinical medicine, and physicians are constantly seeking better methods for achieving efficient and secure closure of both surgical and traumatic wounds. There is great demand for tissue adhesives to replace or augment sutures and staples for wound repair, as well as adhesive materials for hemorrhage control. An effective tissue adhesive has the potential to reduce operating times, lessen the bleeding and leakage from wounds, lower the incidence of complications, and reduce hospital stays. Such an adhesive will save time and money, as well as lessen morbidity and mortality in surgical patients. Extensive progress has been made in the development of adhesive biomaterials, with several platforms available for clinical use. Continued innovation in this field is essential for patient safety. This chapter reviews the current status of adhesive biomaterials for tissue reconstruction and highlights new developments in bioadhesive platforms.

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Bhatia, S.K. (2010). Traumatic Injuries . In: Biomaterials for Clinical Applications. Springer, New York, NY. https://doi.org/10.1007/978-1-4419-6920-0_10

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