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Resistance to Antifungal Drugs

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Essentials of Clinical Mycology

Abstract

Fungal infections caused by fungal pathogens are common in immunocompromised hosts. Candida spp. comprise the major yeast species recovered from infected individuals; however, other yeast species such as Cryptococcus neoformans might also be isolated. Among filamentous fungi causing infections in human, Aspergillus fumigatus has a dominant position, and this fungal species is linked to a high mortality [1]. Not only are a restricted number of antifungal agents available to treat these infections, but also resistance to antifungal treatment can occur. Table 1 summarizes the activity of known antifungal agents in several yeast species and A. fumigatus.

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Authors and Affiliations

  1. Institute of Microbiology, University of Lausanne and University Hospital Center, Lausanne, Switzerland

    Dominique Sanglard

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  1. Dominique Sanglard
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Editors and Affiliations

  1. Veterans Affairs Ann Arbor Healthcare, Professor of Internal Medicine, University of Michigan Medical School, 2215 Fuller Road, Ann Arbor, 48105, Michigan, USA

    Carol A. Kauffman

  2. Division of Infectious Diseases, University of Alabama at Birmingham, 1900 University Blvd., Birmingham, 35294, Alabama, USA

    Peter G. Pappas

  3. Division of Infectious Diseases, Wayne State University School of Medicin, 3990 John R Street, Detroit, 48201, Michigan, USA

    Jack D. Sobel

  4. School of Medicine, Professor Emeritus of Medicine, University of Alabama at Birmingham, 1530 3rd Avenue South, Birmingham, 35294, Alabama, USA

    William E. Dismukes

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Sanglard, D. (2011). Resistance to Antifungal Drugs. In: Kauffman, C., Pappas, P., Sobel, J., Dismukes, W. (eds) Essentials of Clinical Mycology. Springer, New York, NY. https://doi.org/10.1007/978-1-4419-6640-7_9

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