Skip to main content
SpringerLink
Log in
Book cover

Encyclopedia of Autism Spectrum Disorders pp 1986–1987Cite as

Navane (Thiothixene)

  • Reference work entry

  • 65 Accesses

Definition

One of the first-generation neuroleptic (major tranquilizer) medications, thiothixene, is of medium potency. Like other agents in this class, its primary mode of action is through the dopamine neurotransmitter system. Compared to the newer, atypical neuroleptics (several of which have been approved for treatment of autism), these earlier agents were more likely to cause various side effects. These have been widely used for decades in the treatment of psychosis (particularly schizophrenia) but also have been used to treat maladaptive behaviors in autism (stereotyped movements, agitation, and self-injurious behaviors). Side effects of this medication can include muscle stiffness, dry mouth, weight gain, and a cluster of features often referred to as extrapyramidal symptoms (restlessness and movement problems that resemble some aspects of Parkinson’s disease). Some of the side effects can be treated by anticholinergic agents like diphenhydramine. The most serious long-term side...

This is a preview of subscription content, log in via an institution.

Chapter
USD   29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD   1,799.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever

Tax calculation will be finalised at checkout

Purchases are for personal use only

Learn about institutional subscriptions

References and Readings

  • Scahill, L. (2008). How do I decide whether or not to use medication for my child with autism? Should I try behavior therapy first? Journal of Autism & Developmental Disorders, 38(6), 1197–1198.

    Article  Google Scholar 

  • Scahill, L., & Martin, A. (2005). Psychopharmacology. In F. R. Volkmar, A. Klin, R. Paul, & D. J. Cohen (Eds.), Handbook of autism and pervasive developmental disorders (Vol. 2, pp. 1102–1122). Hoboken, NJ: Wiley.

    Google Scholar 

  • Scheffer, R. E. (2006). Psychopharmacology: Clinical implications of brain neurochemistry. Pediatric Clinics of North America, 53(4), 767–775.

    Article  PubMed  Google Scholar 

  • White, S., Scahill, L., Klin, A., Koenig, K., & Volkmar, F. (2007). Educational placements and service use patterns of individuals with autism spectrum disorders. Journal of Autism & Developmental Disorders, 37(8), 1403–1412.

    Article  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Director – Child Study Center, Irving B. Harris Professor of Child Psychiatry, Pediatrics and Psychology, School of Medicine, Yale University, 230 South Frontage Road, P.O. Box 207900, New Haven, 06520-7900, CT, USA

    Dr. Fred R. Volkmar (Director, Child Study Center, Irving B. Harris Professor of Child Psychiatry, Pediatrics and Psychology)

Authors
  1. Dr. Fred R. Volkmar
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Fred R. Volkmar .

Editor information

Editors and Affiliations

  1. Irving B. Harris Professor of Child Psychiatry, Pediatrics and Psychology Yale University School of Medicine, Chief, Child Psychiatry Children's Hospital at Yale-New Haven Child Study Center, New Haven, CT, USA

    Fred R. Volkmar (Director, Child Study Center) (Director, Child Study Center)

Rights and permissions

Reprints and permissions

Copyright information

© 2013 Springer Science+Business Media New York

About this entry

Cite this entry

Volkmar, F.R. (2013). Navane (Thiothixene). In: Volkmar, F.R. (eds) Encyclopedia of Autism Spectrum Disorders. Springer, New York, NY. https://doi.org/10.1007/978-1-4419-1698-3_1833

Download citation

  • DOI: https://doi.org/10.1007/978-1-4419-1698-3_1833

  • Publisher Name: Springer, New York, NY

  • Print ISBN: 978-1-4419-1697-6

  • Online ISBN: 978-1-4419-1698-3

  • eBook Packages: Behavioral Science

Publish with us

Policies and ethics

Search

Navigation