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The Application of Cell Based Biosensor and Biochip for EnvironmentalMonitoring

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Atmospheric and Biological Environmental Monitoring

Abstract

The cell based biosensor has outstanding advantages in aspect of environmental monitoring, comparing with DNA or protein based biosensor. Various cell based biosensors to detect toxic chemicals have been researched in few decades and applied directly to environmental fields. In this study, some key technologies such as cell immobilization technology, on-chip cell cultivation technology, and cell viability detection technology required to develop cell based biosensors are categorized and briefly discussed. We suggests that cell based biochip can be applied to environmental monitoring by demonstrating that phenol can be successfully measured by two distinct cell based label-free biochips, SPR based cell chip and electric based cell chip, developed using key technologies.

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Authors and Affiliations

  1. College of Bionano technology, Kyungwon University, Seongnam, Gyunggi-Do, 461-701, Korea

    Junhong Min

  2. Department of Chemical and Bomolecular Engineering, Sogang University, Seoul 121-742, Korea

    Cheol-Heon Yea

  3. Interdisciplenary Program of Integrated Biotechnology, Sogang University, Seoul 121-742, Korea

    Waleed Ahmed El-Said

  4. College of Bionano technology, Kyungwon University, Seongnam, Gyunggi-Do, 461-701, Korea

    Jeong-Woo Choi

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  1. Junhong Min
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  2. Cheol-Heon Yea
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  3. Waleed Ahmed El-Said
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  4. Jeong-Woo Choi
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Editors and Affiliations

  1. Department of Environmental Science and Engineering, Gwangju Institute of Science and Technology (GIST), 261 Cheomdan-gwagiro Bug-gu, Gwangju 500-712, Republic of Korea

    Young J. Kim

  2. Institute of Environmental Physics, University of Heidelberg, Im Neuenheimer Feld 229, D-69120 Heidelberg, Germany

    Ulrich Platt

  3. College of Life Sciences and Biotechnology, Korea University, Seoul 136-701, Republic of Korea

    Man Bock Gu

  4. Health Technology Research Center, National Institute of Advanced Industrial Science and Technology, Midorigaoka, 1-8-31, Ikeda, Osaka 563-8577, Japan

    Hitoshi Iwahashi

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Min, J., Yea, CH., El-Said, W.A., Choi, JW. (2009). The Application of Cell Based Biosensor and Biochip for EnvironmentalMonitoring. In: Kim, Y.J., Platt, U., Gu, M.B., Iwahashi, H. (eds) Atmospheric and Biological Environmental Monitoring. Springer, Dordrecht. https://doi.org/10.1007/978-1-4020-9674-7_18

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