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Autoimmunity and Autoimmune Diseases in the Elderly

  • Chapter
Handbook on Immunosenescence

Abstract

In the majority of papers dealing with immune system changes, higher prevalence of autoimmunity and autoimmune diseases among elderly people is stressed as one of the factors confirming the changes of immune system function in aging. This statement is repeated for a very long time and most of the authors treat it as a “stone-carved” truth. However, we will show below that, as we look into this problem in details, there are not so many diseases which appear in the elderly population more frequent to the younger ones. So, where is the problem and why is that so?

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Authors and Affiliations

  1. Department of Pathophysiology, Medical University of Gdańsk, Debinki 7, Gdańsk, 80-211, Poland

    Ewa Bryl & Jacek M. Witkowski

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  1. Ewa Bryl
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  2. Jacek M. Witkowski
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Editors and Affiliations

  1. Research Center on Aging, Department of Medicine, Immunology Graduate Programme, Faculty of Medicine, University of Sherbrooke, 1036 Rue Belvedere, J1H 4C4, Sherbrooke, Quebec, Canada

    Tamas Fulop

  2. Department of Experimental Pathalogy, CIG Interdepartmental Center “L. Galvani” University of Bologna, Via San Giacomo 12, 40126, Bologna, Italy

    Claudio Franceschi

  3. Institute for Health and Life Sciences, 4-6-22 Kohinato, Bunkyo-ku, Tokyo, 112-0006, Japan

    Katsuiku Hirokawa

  4. ZMF - Zentrum Med. Forschung Abt. Transplant./ Immunologie, University of Tübingen, Waldhörnlestr. 22, 72072, Tübingen, Germany

    Graham Pawelec

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Bryl, E., Witkowski, J.M. (2009). Autoimmunity and Autoimmune Diseases in the Elderly. In: Fulop, T., Franceschi, C., Hirokawa, K., Pawelec, G. (eds) Handbook on Immunosenescence. Springer, Dordrecht. https://doi.org/10.1007/978-1-4020-9063-9_51

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