Within the United States Environmental Protection Agency (EPA), the Office of Pollution Prevention and Toxics (OPPT) is responsible for implementing the Toxic Substances Control Act (TSCA) of 1976 and the Pollution Prevention Act (PPA) of 1990 [1,2]. Before TSCA was passed, it was not known how many chemicals were in commerce in the U.S., where they were being produced and/or imported, and in what quantities they were being produced and/or imported.
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Auer, C., Alter, J. (2007). The Management of Industrial Chemicals in the USA. In: Leeuwen, C.v., Vermeire, T. (eds) Risk Assessment of Chemicals. Springer, Dordrecht. https://doi.org/10.1007/978-1-4020-6102-8_13
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