Synonyms
Vaccination, passive; Inoculation, passive; Application of immune globulins; Immune prophylaxis
Definition
Passive immunization is a process by which antibodies are introduced into an organism. These antibodies, which are directed against a particular germ, provide an immediate protection and prevent any disease which may be caused by that particular pathogen.
Basic Characteristics
History
The first steps in passive immunization were taken in the late 19th century. The German physician and scientist Emil von Behring and the Japanese physician and bacteriologist Shibasaburo Kitasato worked together in Berlin, focusing their research on tetanus and diphtheria (http://nobelprize.org/nobel_prizes/medicine/articles/behring/index.html). In their immunological experiments they introduced blood from infected animals into healthy animals. Animals vaccinated by this technique proved to be immune against the given germ or its toxin. From this observation the scientists concluded...
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References
Deutsche Gesellschaft für pädiatrische Infektiologie e.V. (DGPI) (2003) Handbuch Infektionen bei Kindern und Jugendlichen, 4th edn. Futuramed, München
Gorbach SL, Bartlett JG, Blacklow NR (2004) Infectious diseases, 3rd edn. Lippincott Williams & Wilkins, Philadelphia
Mandell GL, Bennett JE, Dolin R (2004) Principles an practice of infectious diseases, 6th edn. Churchill Livingstone, New York
Murray PR, Baron EJ, Jorgensen JH, Pfaller MA, Yolken RH (2003) Manual of clinical microbiology, 8th edn. American Society for Microbiology, Washington, D.C.
http://nobelprize.org/nobel_prizes/medicine/articles/behring/index.html.
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© 2008 Springer-Verlag
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Korn, M. (2008). Immunization, Passive . In: Kirch, W. (eds) Encyclopedia of Public Health. Springer, Dordrecht. https://doi.org/10.1007/978-1-4020-5614-7_1630
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DOI: https://doi.org/10.1007/978-1-4020-5614-7_1630
Publisher Name: Springer, Dordrecht
Print ISBN: 978-1-4020-5613-0
Online ISBN: 978-1-4020-5614-7
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