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Pop-Out Myocardial Infarction Induction in Mice

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Experimental Models of Cardiovascular Diseases

Part of the book series: Methods in Molecular Biology ((MIMB,volume 2803))

Abstract

Myocardial infarction (MI) in mice is a widely used surgical model in preclinical cardiac repair studies to recapitulate human cardiovascular ischemic disease. Induction of reproducible infarct size is crucial for quantitative and analytical purpose. Here we describe a quick and reliable method to induce consistent infarct size in mice in less than a minute.

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Authors and Affiliations

  1. Icahn School of Medicine at Mount Sinai, Department of Cardiology, New York, NY, USA

    Bingyan J. Wang & Hina W. Chaudhry

Authors
  1. Bingyan J. Wang
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  2. Hina W. Chaudhry
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Corresponding author

Correspondence to Hina W. Chaudhry .

Editor information

Editors and Affiliations

  1. Cardiovascular Research Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA

    Kiyotake Ishikawa

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© 2024 The Author(s), under exclusive license to Springer Science+Business Media, LLC, part of Springer Nature

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Wang, B.J., Chaudhry, H.W. (2024). Pop-Out Myocardial Infarction Induction in Mice. In: Ishikawa, K. (eds) Experimental Models of Cardiovascular Diseases. Methods in Molecular Biology, vol 2803. Humana, New York, NY. https://doi.org/10.1007/978-1-0716-3846-0_10

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  • DOI: https://doi.org/10.1007/978-1-0716-3846-0_10

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  • Publisher Name: Humana, New York, NY

  • Print ISBN: 978-1-0716-3845-3

  • Online ISBN: 978-1-0716-3846-0

  • eBook Packages: Springer Protocols

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