Abstract
Emerging research has highlighted the importance of metabolic pathways and metabolites in dictating immune cell lineage decisions during thymocyte development. Here, we discuss several complementary approaches, including flow cytometry, metabolic flux, and transcriptome analyses, to characterize the dynamic changes in metabolic profiles associated with invariant natural killer T cell development.
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Acknowledgments
The authors thank Dr. Hao Shi for edits and Dr. Nicole Chapman for contributing edits and writing for this manuscript. This work was supported by NIH AI105887, AI131703, AI140761, AI150241, AI150514, CA221290, and CA250533 (to H.C.).
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Raynor, J.L., Chi, H. (2021). Investigating the Dynamic Changes in iNKT Cell Metabolic Profiles During Development. In: Liu, C. (eds) Invariant Natural Killer T-Cells. Methods in Molecular Biology, vol 2388. Humana, New York, NY. https://doi.org/10.1007/978-1-0716-1775-5_17
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DOI: https://doi.org/10.1007/978-1-0716-1775-5_17
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