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Communicating Complex Results of Cerebrospinal Fluid Analysis

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Cerebrospinal Fluid Biomarkers

Part of the book series: Neuromethods ((NM,volume 168))

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Abstract

Cerebrospinal fluid (CSF) analysis requires a combined assessment of multiple tests to establish diagnosis. Some result combinations require the application of specific rules, based on mathematical formulae to supply a correct result interpretation. This chapter addresses some typical pitfalls in the interpretation of blood contaminated CSF, interpretation of the antibody specifity index, and markers of dementia. The text output of a knowledge-based system combined with a visually oriented report form facilitates the recognition of these typical but often not apparent disease patterns.

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Notes

  1. 1.

    http://mdilablink.com. Developed by the chapter authors, that gladly provide additional information.

Abbreviations

ASI:

Antibody specificity index

CBC:

Complete blood differential

CSF :

cerebrospinal fluid

Ec:

Erythrocytes

Leuco:

Leucocytes

Mono:

Mononuclear cells

NMO:

Neuromyelitis optica (M. Devic)

OCB:

Oligoclonal bands

Poly:

Polymorphic cells

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Author information

Authors and Affiliations

  1. Medica Medical Laboratories Dr. F. Käppeli, Zurich, Switzerland

    Axel Regeniter & Werner H. Siede

Authors
  1. Axel Regeniter
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  2. Werner H. Siede
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Corresponding author

Correspondence to Axel Regeniter .

Editor information

Editors and Affiliations

  1. Neurochemistry Laboratory, Department of Clinical Chemistry, Amsterdam Neuroscience, Amsterdam University Medical Centre, Vrije Universiteit, Amsterdam, The Netherlands

    Charlotte E. Teunissen

  2. Department of Psychiatry and Neurochemistry, The Sahlgrenska Academy at the University of Gothernburg, Mölndal, Sweden

    Henrik Zetterberg

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Regeniter, A., Siede, W.H. (2021). Communicating Complex Results of Cerebrospinal Fluid Analysis. In: Teunissen, C.E., Zetterberg, H. (eds) Cerebrospinal Fluid Biomarkers. Neuromethods, vol 168. Humana, New York, NY. https://doi.org/10.1007/978-1-0716-1319-1_9

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  • DOI: https://doi.org/10.1007/978-1-0716-1319-1_9

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  • Publisher Name: Humana, New York, NY

  • Print ISBN: 978-1-0716-1318-4

  • Online ISBN: 978-1-0716-1319-1

  • eBook Packages: Springer Protocols

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