Abstract
In this chapter, we have developed a method to estimate the efficiency of the drugs and the numbers of infectious and noninfectious HIV in HIV-infected individuals treated with antiretroviral drugs. As an illustration, we have applied the method to some clinical and laboratory data of an AIDS patient treated with various antiviral drugs. For this individual, the estimates show that the HAART protocol has effectively controlled the number of infectious HIV virus to below 400/ml copies although the total number of HIV copies was very high in some intervals.
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Tan, WY., Zhang, P., Xiong, X., Flynn, P. (2007). Assessment of Treatment Effects on HIV Pathogenesis Under Treatment By State Space Models. In: Auget, JL., Balakrishnan, N., Mesbah, M., Molenberghs, G. (eds) Advances in Statistical Methods for the Health Sciences. Statistics for Industry and Technology. Birkhäuser Boston. https://doi.org/10.1007/978-0-8176-4542-7_20
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DOI: https://doi.org/10.1007/978-0-8176-4542-7_20
Publisher Name: Birkhäuser Boston
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