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Hair Loss in Lupus Erythematosus

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Encyclopedia of Medical Immunology

Synonyms

Alopecia in systemic disease; Discoid scarring alopecia; Hair loss in SLE; Lupus hair loss

Definition

The clinical presentation of lupus erythematosus (LE) may be confined to cutaneous disease or may involve various internal organs. Alopecia may occur with cutaneous and/or systemic lupus erythematosus. Hair loss over the scalp may range from localized scarring type of alopecia to non-scarring hair loss.

Discoid Lupus Erythematosus

Epidemiology

According to the Gilliam classification for cutaneous LE, DLE is considered an LE-specific skin lesion under the chronic cutaneous LE (CCLE) category. It is the most common clinical presentation of CCLE and commonly affects the scalp.

In patients with DLE, the scalp may be involved in 34–60 % of cases (Wilson et al. 1992; De Berker et al. 1992) and may be the only site affected in 10 % (Sontheimer and Mccauliffe 2002). Scalp DLE can be purely cutaneous or may be associated with SLE. DLE lesions may be the first clinical manifestation of...

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Author information

Authors and Affiliations

  1. Department of Dermatology, University of British Columbia, 835 west 10th Ave, Vancouver, BC, Canada

    M. J. Kristine Bunagan, Nusrat Banka & Jerry Shapiro

  2. The Ronald O. Perelman Department of Dermatology, New York University School of Medicine, 240 East 38th Street, 11th Floor Administration, New York, NY, 10016, USA

    Jerry Shapiro

Authors
  1. M. J. Kristine Bunagan
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  2. Nusrat Banka
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  3. Jerry Shapiro
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Corresponding author

Correspondence to M. J. Kristine Bunagan .

Editor information

Editors and Affiliations

  1. Department of Biochemistry and Molecular Biology, Monash University, Clayton, Victoria, Australia

    Ian R. Mackay

  2. Center for Autoimmune Disease Research, Department of Molecular Microbiology and Immunology, Department of Pathology, Johns Hopkins University, Baltimore, MD, USA

    Noel R. Rose

  3. The Feinstein Institute for Medical Research, Manhasset, NY, USA

    Betty Diamond

  4. The Feinstein Institute for Medical Research, Manhasset, NY, USA

    Anne Davidson

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Bunagan, M.J.K., Banka, N., Shapiro, J. (2014). Hair Loss in Lupus Erythematosus. In: Mackay, I.R., Rose, N.R., Diamond, B., Davidson, A. (eds) Encyclopedia of Medical Immunology. Springer, New York, NY. https://doi.org/10.1007/978-0-387-84828-0_547

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  • DOI: https://doi.org/10.1007/978-0-387-84828-0_547

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  • Publisher Name: Springer, New York, NY

  • Print ISBN: 978-0-387-84827-3

  • Online ISBN: 978-0-387-84828-0

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