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Management of Postoperative Arrhythmias

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Surgical Intensive Care Medicine

Abstract

Cardiac arrhythmias in the perioperative period are common and a major source of morbidity. The most common sustained cardiac arrhythmia, atrial fibrillation (AF), occurs in 30–40% of patients after cardiac surgery, and in up to 4% of patients after noncardiac surgery. Such arrhythmias are responsible for increased length of hospital stay as well as increased healthcare costs. This chapter will address the diagnosis and treatment of perioperative arrhythmias and will suggest simple, cost-effective strategies for evaluation and prevention. As many patients undergoing general and cardiac surgical procedures have implanted arrhythmia control devices (pacemakers and/or defibrillators), this chapter will also discuss the perioperative care of these patients.

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References

  1. Heintz KM, Hollenberg SM. Perioperative cardiac issues: postoperative arrhythmias. Surg Clin North Am. 2005;85:1103–1114.

    Article  PubMed  Google Scholar 

  2. Maisel WH, Rawn JD, Stevenson WG. Atrial fibrillation after cardiac surgery. Ann Intern Med. 2001;135:1061–1073.

    Article  PubMed  CAS  Google Scholar 

  3. Polanczyk CA, Goldman L, Marcantonio ER, et al. Supraventricular arrhythmia in patients having noncardiac surgery: clinical correlates and effect on length of stay. Ann Intern Med. 1998;129:279–285.

    Article  PubMed  CAS  Google Scholar 

  4. Adams DH, Filsoufi F, Antman EM. Medical management of the patient undergoing cardiac surgery. In: Zipes D, Libby P, Bonow R, et al., editors. Braunwald’s heart disease: a text book of cardiovascular medicine. Philadelphia: Elsevier; 2005. p. 1993–2020.

    Google Scholar 

  5. Wagner GS, Marriott HJ. Marriott’s practical electrocardiography. 10th ed. Baltimore: Lippincott Williams & Wilkins; 2001.

    Google Scholar 

  6. Rho RW, Bridges CR, Kocovic D. Management of postoperative arrhythmias. Semin Thorac Cardiovasc Surg. 2000;12:349–361.

    Article  PubMed  CAS  Google Scholar 

  7. Creswell LL, Schuessler RB, Rosenbloom M, Cox JL. Hazards of postoperative atrial arrhythmias. Ann Thorac Surg. 1993;56:539–549.

    Article  PubMed  CAS  Google Scholar 

  8. Chung MK. Cardiac surgery: postoperative arrhythmias. Crit Care Med. 2000;28(Suppl)):N136–N144.

    Article  PubMed  CAS  Google Scholar 

  9. Aranki SF, Shaw DP, Adams DH, et al. Predictors of atrial fibrillation after coronary artery surgery. Circulation. 1996;94:390–397.

    Article  PubMed  CAS  Google Scholar 

  10. Kannel WB, Abbott RD, Savage DD, et al. Epidemiologic features of atrial fibrillation. The Framingham Study. N Engl J Med. 1982;306:1018–1022.

    Article  PubMed  CAS  Google Scholar 

  11. Zaman AG, Archbold A, Helft G, et al. Atrial fibrillation after coronary bypass surgery. A model for preoperative risk stratification. Circulation. 2000;101:1403–1408.

    Article  PubMed  CAS  Google Scholar 

  12. Matthew JP, Parks R, Savinio J, et al. Atrial fibrillation following coronary artery bypass graft surgery: predictors, outcomes, and resource utilization. JAMA. 1996;276:300–306.

    Article  Google Scholar 

  13. Fuller JA, Adams GC, Buxton B. Atrial fibrillation after coronary bypass grafting: is it a disorder of the elderly? J Thorac Cardiovasc Surg. 1989;97:821–825.

    PubMed  CAS  Google Scholar 

  14. Waldo AL, MacLean WAH. Diagnosis and treatment of arrhythmias following open heart surgery: emphasis on the use of epicardial wire electrodes. New York: Futura Publishing; 1980.

    Google Scholar 

  15. Goldman L. Supraventricular tachyarrhythmias in hospitalized adults after surgery. Clinical correlates in patients over 40 years of age after major noncardiac surgery. Chest. 1978;73:450–454.

    Article  PubMed  CAS  Google Scholar 

  16. Almassi GH, Schowalter T, Nicolosi AC, et al. Atrial fibrillation after cardiac surgery: a major morbid event? Ann Surg. 1997;226:501–513.

    Article  PubMed  CAS  Google Scholar 

  17. Angelini GD, Penny WJ, el-Ghamary F, et al. The incidence and significance of early pericardial effusion after open-heart surgery. Eur J Cardiothorac Surg. 1987;1:165–168.

    Article  PubMed  CAS  Google Scholar 

  18. Wahr JA, Parks R, Boisvert R, et al. Perioperative serum potassium levels and perioperative outcomes in cardiac surgery patients. Multicenter Study of Perioperative Ischemia Research Group. JAMA. 1999;281:2203–2210.

    Article  PubMed  CAS  Google Scholar 

  19. Lowe JE, Hendry PJ, Hendrickson SC, et al. Intraoperative identification of cardiac patients at risk to develop postoperative atrial fibrillation. Ann Surg. 1991;213:388–392.

    Article  PubMed  CAS  Google Scholar 

  20. Tsikouris JP, Kluger J, Song J, et al. Changes in P-wave dispersion and P-wave duration after open heart surgery are associated with the peak incidence of atrial fibrillation. Heart Lung. 2001;30:466–471.

    Article  PubMed  CAS  Google Scholar 

  21. Crystal E, Garfinkle MS, Connolly SS, et al. Interventions for preventing post-operative atrial fibrillation in patients undergoing heart surgery. Cochrane Database Sys Rev 2004;(4):CD003611.

    Google Scholar 

  22. Andrews TC, Reimold SC, Berlin JA, Entman EM. Prevention of supraventricular arrhythmias after coronary bypass surgery. A meta-analysis of randomized control trials. Circulation. 1991;84(5 Suppl):III236–III244.

    PubMed  CAS  Google Scholar 

  23. Mohr R, Smolinsky A, Goor DA. Prevention of supraventricular arrhythmia with low-dose propanolol after coronary artery bypass grafting. J Thorac Cardiovasc Surg. 1981;81:840–845.

    PubMed  CAS  Google Scholar 

  24. White HD, Antman GM, Glynn MA, et al. Efficacy and safety of timolol for prevention of supraventricular tachyarrhythmias after coronary bypass surgery. Circulation. 1984;70:479–484.

    Article  PubMed  CAS  Google Scholar 

  25. Stephenson LW, MacVaugh H, Tomasello DN, et al. Propanolol for the prevention of postoperative cardiac arrhythmias: a randomized study. Ann Thorac Surg. 1980;29:113–116.

    Article  PubMed  CAS  Google Scholar 

  26. Kowey PR, Taylor JE, Rials SJ, et al. Meta-analysis of the effectiveness of prophylactic drug therapy in preventing supraventricular arrhythmia after coronary bypass grafting. Am J Cardiol. 1992;69:963–965.

    Article  PubMed  CAS  Google Scholar 

  27. Eagle KA, Guyton RA, Davidoff R, et al. ACC/AHA 2004 guideline update for coronary bypass graft surgery: summary article. A report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (Committee to Update the 1999 Guidelines for Coronary Bypass Graft Surgery). J Am Coll Cardiol. 2004;44:1146.

    Article  Google Scholar 

  28. Gomes JA, Ip J, Santoni-Rugiu F, et al. Oral d, l sotalol reduces the incidence of postoperative atrial fibrillation in coronary artery bypass surgery patients: a randomize, double-blind, placebo-controlled study. J Am Coll Cardiol. 1999;34:334–339.

    Article  PubMed  CAS  Google Scholar 

  29. Suttorp MJ, Kingma JH, Peels HO, et al. Effectiveness of sotalol in preventing supraventricular tachyarrhythmias shortly after coronary bypass grafting. Am J Cardiol. 1991;68:1163–1169.

    Article  PubMed  CAS  Google Scholar 

  30. Evrard P, Gonzalez M, Jamart J, et al. Prophylaxis of supraventricular and ventricular arrhythmias after coronary artery bypass grafting with low-dose sotalol. Ann Thorac Surg. 2000;70:151–156.

    Article  PubMed  CAS  Google Scholar 

  31. Parikka H, Toivonen L, Heikkila L, et al. Comparison of sotalol and metoprolol in the prevention of atrial fibrillation after coronary artery bypass surgery. J Cardiovasc Pharmacol. 1998;31:67–73.

    Article  PubMed  CAS  Google Scholar 

  32. Sanjuan R, Blasco M, Carbonell N, et al. Preoperative use of sotalol versus atenolol for atrial fibrillation after cardiac surgery. Ann Thorac Surg. 2004;77:838.

    Article  PubMed  Google Scholar 

  33. Aasbo JD, Lawrence AT, Krishnan K, et al. Amiodarone prophylaxis reduces major cardiovascular morbidity and length of stay after cardiac surgery: a meta-analysis. Ann Intern Med. 2005;143:327.

    Article  PubMed  CAS  Google Scholar 

  34. Daoud EG, Strickberger SA, Man KC, et al. Preoperative amiodarone as prophylaxis against atrial fibrillation after heart surgery. N Engl J Med. 1997;337:1785–1791.

    Article  PubMed  CAS  Google Scholar 

  35. Mitchell LB, Exner DV, Wyse DG, et al. Prophylactic oral amiodarone for the prevention of arrhythmias that begin early after revascularization, valve replacement, or repair: PAPABEAR: a randomized controlled trial. JAMA. 2005;294:3093–3100.

    Article  PubMed  CAS  Google Scholar 

  36. Guarnieri T, Nolan S, Gottleib SO, et al. Intravenous amiodarone for the prevention of atrial fibrillation after open heart surgery: The Amiodarone Reduction in Coronary Heart (ARCH) trial. J Am Coll Cardiol. 1999;34:343–347.

    Article  PubMed  CAS  Google Scholar 

  37. Kerstein J, Soodan A, Qamar M, et al. Giving IV and oral amiodarone preoperatively for the prevention of postoperative atrial fibrillation in patients undergoing coronary artery bypass surgery: the GAP study. Chest. 2004;126:716–724.

    Article  PubMed  CAS  Google Scholar 

  38. Smith EE, Shore DF, Monro JL, et al. Oral verapamil fails to prevent supraventricular tachycardia following coronary artery surgery. Int J Cardiol. 1987;9:37.

    Article  Google Scholar 

  39. Malhotra R, Mishra M, Kler TS, et al. Cardioprotective effects of diltiazem infusion in the perioperative period. Eur J Cardiothorac Surg. 1997;12:420.

    Article  PubMed  CAS  Google Scholar 

  40. Gerstenfeld EP, Hill MR, French SN, et al. Evaluation of right atrial and biatrial temporary pacing for the prevention of atrial fibrillation after coronary artery bypass surgery. J Am Coll Cardiol. 1999;33:1981–1988.

    Article  PubMed  CAS  Google Scholar 

  41. Kurz DJ, Naegeli B, Kunz M, et al. Epicardial, biatrial synchronous pacing for prevention of atrial fibrillation after cardiac surgery. Pacing Clin Electrophysiol. 1999;22:721–726.

    Article  PubMed  CAS  Google Scholar 

  42. Chung M, Augostini R, Asher C, et al. Ineffectiveness and potential proarrhythmia of atrial pacing for the prevention of atrial fibrillation prevention after coronary artery bypass grafting. Ann Thorac Surg. 2000;69:1057–1063.

    Article  PubMed  CAS  Google Scholar 

  43. Greenberg MD, Katz NM, Iuliano S, et al. Atrial pacing for the prevention of atrial fibrillation after cardiovascular surgery. J Am Coll Cardiol. 2000;35:1416–1422.

    Article  PubMed  CAS  Google Scholar 

  44. Blommaert D, Gonzalez M, Mucumbitsi J, et al. Effective prevention of atrial fibrillation by continuous atrial overdrive pacing after coronary bypass surgery. J Am Coll Cardiol. 2000;35:1411–1415.

    Article  PubMed  CAS  Google Scholar 

  45. Fan K, Lee KL, Chiu CS, et al. Effects of biatrial pacing in prevention of postoperative atrial fibrillation after coronary artery bypass surgery. Circulation. 2000;102:755–760.

    Article  PubMed  CAS  Google Scholar 

  46. Daoud EG, Dabir R, Archambeau M, et al. Randomized, double-blind trial of simultaneous right and left atrial epicardial pacing for prevention of post-open heart surgery atrial fibrillation. Circulation. 2000;102:1382.

    Article  Google Scholar 

  47. Ellenbogen KA, Stambler BS, Wood MA, et al. Efficacy of intravenous ibutilide for rapid termination of atrial fibrillation and atrial flutter: a dose-responsive study. J Am Coll Cardiol. 1991;28(1):130–136.

    Article  Google Scholar 

  48. Howard PA. Ibutilide: an antiarrhythmic agent for the treatment of atrial fibrillation or flutter. Ann Pharmachother. 1999;33:38–47.

    Article  CAS  Google Scholar 

  49. The Atrial Fibrillation Follow-up Investigation of Rhythm Management (AFFIRM) Investigators. A Comparison of rate control and rhythm control in patients with atrial fibrillation. N Engl J Med. 2002;347(23):1825–1833.

    Article  Google Scholar 

  50. Myers MG, Alnemri K. Rate control therapy for atrial fibrillation following coronary bypass surgery. Can J Cardiol. 1998;14:1363–1366.

    PubMed  CAS  Google Scholar 

  51. McKeown PP. ACCP guidelines for the prevention and management of postoperative atrial fibrillation after cardiac surgery. Chest. 2005;128(2 Suppl):1S–5S.

    Article  PubMed  Google Scholar 

  52. Fuster V, Rydén LE, Cannom DS, et al. ACC/AHA/ESC 2006 guidelines for the management of patients with atrial fibrillation – executive summary: a report of the American College of Cardiology/American Heart Association Task Force and the European Society of Cardiology Committee for Practice Guidelines (Writing Committee to Revise the 2001 Guidelines for the Management of Patients With Atrial Fibrillation). J Am Coll Cardiol. 2006;48:854–906.

    Article  PubMed  Google Scholar 

  53. Topol EJ, Lerman BB, Baughman KL, et al. De novo refractory ventricular tachyarrhythmias after coronary revascularization. Am J Cardiol. 1986;57:57–59.

    Article  PubMed  CAS  Google Scholar 

  54. Kron IL, diMarco JP, Harman PK, et al. Unanticipated postoperative ventricular tachyarrhythmias. Ann Thorac Surg. 1984;38:317–322.

    Article  PubMed  CAS  Google Scholar 

  55. Steinberg JS, Gaur A, Sciacca R, et al. New onset sustained ventricular tachycardia after surgery. Circulation. 1999;99:903–908.

    Article  PubMed  CAS  Google Scholar 

  56. Smith RC, Leung JM, Keith FM, et al. Ventricular dysrhythmias in patients undergoing coronary bypass graft surgery: incidence, characteristics, and prognostic importance. Am Heart J. 1992;123:73–81.

    Article  PubMed  CAS  Google Scholar 

  57. Huikuri HV, Yli-Mayry S, Korhonen UR, et al. Prevalence and prognostic significance of complex ventricular arrhythmias after coronary arterial bypass graft surgery. Int J Cardiol. 1990;27:333–339.

    Article  PubMed  CAS  Google Scholar 

  58. Rubin DA, Niemski KE, Monteferrant JC, et al. Ventricular arrhythmias after coronary bypass surgery: incidence, risk factors and long-term prognosis. J Am Coll Cardiol. 1985;6:307–310.

    Article  PubMed  CAS  Google Scholar 

  59. Olgin JE. Zipes DE. Specific arrhythmias: diagnosis and treatment. In: Zipes DP, Libby P, Bonow RO, et al., editors. Braunwald’s heart disease. A textbook of cardiovascular medicine. 7th ed. Elsevier: Philadelphia; 2005.

    Google Scholar 

  60. Pinto RP, Romerill DB, Nasser WK, et al. Prognosis of patients with frequent premature ventricular complexes and nonsustained ventricular tachycardia after coronary artery bypass graft surgery. Clin Cardiol. 1996;19:321–3324.

    Article  PubMed  CAS  Google Scholar 

  61. Buxton AE, Lee KL, Fisher JD, et al. The Multicenter Unsustained Tachycardia Trial Investigators. A randomized study of the prevention of sudden death in patients with coronary artery disease. N Engl J Med. 1999;341:1882–1890.

    Article  PubMed  CAS  Google Scholar 

  62. Moss AJ, Hall WJ, Cannom DS, et al. The Multicenter Automatic Defibrillator Implantation Trial Investigators. Improved survival with an implantable defibrillator in patients with coronary disease at high risk for ventricular arrhythmia. N Engl J Med. 1996;335:1933–1940.

    Article  PubMed  CAS  Google Scholar 

  63. Eagle KA, Berger PB, Calkins H, et al. ACC/AHA guideline update for perioperative cardiovascular evaluation for noncardiac surgery; executive summary: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (Committee to Update the 1996 Guidelines on Perioperative Cardiovascular Evaluation for Noncardiac Surgery. J Am Coll Cardiol. 2002;39:542–553.

    Article  PubMed  Google Scholar 

  64. Mangano DT, Layug EL, Wallace A, et al. Effect of atenolol on mortality and cardiovascular morbidity after noncardiac surgery. Multicenter study of Perioperative Ischemia Research Group. N Engl J Med. 1996;335(23):1713–1720.

    Article  PubMed  CAS  Google Scholar 

  65. O’Neil-Callahan K, Katsimaglis G, Tepper MR, et al. Statins decrease perioperative cardiac complications in patients undergoing noncardiac vascular surgery. J Am Coll Cardiol. 2005;45:336–342.

    Article  PubMed  Google Scholar 

  66. Mitchell LB, Powell JL, Gillis AM, et al. Are lipid lowering drugs also antiarrhythmic drugs? An analysis of the Antiarrhythmics Versus Implantable Defibrillators (AVID) trial. J Am Coll Cardiol. 2003;42:81–87.

    Article  PubMed  CAS  Google Scholar 

  67. Bolad I, MacLellan C, Karanam S, et al. Effectiveness of early implantation for cardioverter defibrillator for postoperative ventricular tachyarrhythmia. Am J Cardiol. 2004;94:376–378.

    Article  PubMed  Google Scholar 

  68. American Heart Association. Advanced Cardiovascular Life Support Provider Manual 2006.

    Google Scholar 

  69. Moss AJ, Zareba W, Hall WJ, et al. Multicenter Automatic Defibrillator Implantation Trial II Investigators. Prophylactic implantation of a defibrillator in patients with myocardial infarction and reduced ejection fraction. N Engl J Med. 2002;346:877–883.

    Article  PubMed  Google Scholar 

  70. Bigger JT Jr. Prophylactic use of implanted cardiac defibrillators in patients at high risk for ventricular arrhythmias after coronary-artery bypass graft surgery. N Engl J Med. 1997;337:1569–1575.

    Article  PubMed  Google Scholar 

  71. Baerman JM, Kirsh MM, Buitleir M, et al. Prognostic effect of bundle branch block related to coronary artery bypass grafting. Am J Cardiol. 1987;59:798–803.

    Article  Google Scholar 

  72. Chu A, Califf RM, Pryor DB, et al. Prognostic effect of bundle branch block related to coronary artery bypass grafting. Am J Cardiol. 1987;59:798–803.

    Article  PubMed  CAS  Google Scholar 

  73. Jaeger FJ, Trohman RG, Brener S, et al. Permanent pacing following repeat cardiac valve surgery. Am J Cardiol. 1994;74:505–507.

    Article  PubMed  CAS  Google Scholar 

  74. Brodell GK, Cosgrove D, Schiavone W, et al. Cardiac rhythm and conduction disturbances in patients undergoing mitral valve surgery. Cleve Clin J Med. 1991;58:397–399.

    Article  PubMed  CAS  Google Scholar 

  75. Eriksson P, Hansson PO, Eriksson H, et al. Bundle-branch block in a general male population: the study of men born 1913. Circulation. 1998;98(22):2494–2500.

    Article  PubMed  CAS  Google Scholar 

  76. Wexelman W, Lichstein E, Cunningham JN, et al. Etiology and clinical significance of new fascicular conduction defects following coronary bypass surgery. Am Heart J. 1986;111:923–927.

    Article  PubMed  CAS  Google Scholar 

  77. Gregoratos G, Abrams J, Epstein AE, et al. ACC/AHA/NASPE 2002 Guideline Update for Implantation of Cardiac Pacemakers and Antiarrhythmia Devices: Summary Article. A report of the America College of Cardiology/American Heart Association Task Force on Practice Guidelines (ACC/AHA/NASPE Committee to Update the 1998 Pacemaker Guidelines). Circulation. 2002;106:2145–2161.

    Article  PubMed  Google Scholar 

  78. Hollenberg SM, Dellinger P. Noncardiac surgery: postoperative arrhythmias. Crit Care Med. 2000;28(10 suppl):N145–N150.

    Article  PubMed  CAS  Google Scholar 

  79. Baerman JM, Kirsh MM, de Buitleir HL, et al. Natural history and determinants of conduction defects following coronary bypass surgery. Ann Thorac Surg. 1987;44:150–153.

    Article  PubMed  CAS  Google Scholar 

  80. Emline G, Huang SKS, Pires LA, et al. Prolonged bradyarrhythmias after isolated coronary bypass surgery. Am Heart J. 1993;126:1084–1090.

    Article  Google Scholar 

  81. El-Khally Z, Thibault B, Staniloae CC, et al. Prognostic significance of newly acquired bundle branch block after aortic valve replacement. Am J Cardiol. 2004;94:1008–1011.

    Article  PubMed  Google Scholar 

  82. Glikson M, Dearani JA, Hyberger LK, et al. Indications, effectiveness, and long-term dependency in permanent pacing after cardiac surgery. Am J Cardiol. 1997;80:1309–1313.

    Article  PubMed  CAS  Google Scholar 

  83. Kim MH, Deeb GM, Eagle KA, et al. Complete atrioventricular block after valvular heart surgery and the timing of pacemaker implantation. Am J Cardiol. 2007;87:649–651.

    Article  Google Scholar 

  84. Ellenbogen KA, Wood MA, editors. Cardiac Pacing and ICDS. 4th ed. Malden: Blackwell; 2005.

    Google Scholar 

  85. Practice advisory for the perioperative management of patients with cardiac rhythm management devices: pacemakers and implantable cardioverter-defibrillators. A Report by the America Society of Anesthesiologists Task Force on Perioperative Management of Patients with Cardiac Rhythm Management Devices. Anesthesiology 2005;103:186–198.

    Google Scholar 

  86. Amar D, Zhang H, Heerdt PM, et al. Statin use is associated with a reduction in atrial fibrillation after noncardiac thoracic surgery independent of C-reactive protein. Chest. 2005;128(5):3421–3427.

    Article  PubMed  CAS  Google Scholar 

  87. Calo L, Bianconi L, Furio C, et al. N-3 Fatty acids for the prevention of atrial fibrillation after coronary artery bypass surgery. J Am Coll Cardiol. 2005;45:1723–1728.

    Article  PubMed  CAS  Google Scholar 

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Chung, E.H., Martin, D.T., Martin, D.T. (2010). Management of Postoperative Arrhythmias. In: O’Donnell, J.M., Nácul, F.E. (eds) Surgical Intensive Care Medicine. Springer, Boston, MA. https://doi.org/10.1007/978-0-387-77893-8_21

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