Abstract
The success of aggressive, curative anticancer therapies in pediatric oncology is possible only with intensive supportive-care measures. For example, antimicrobial prophylaxis can reduce infection rates in children undergoing myelosuppressive chemotherapy. Likewise, preemptive, broad-spectrum antibiotic therapy given as treatment for fever and neutropenia has been shown to reduce the mortality rate in this patient population. Furthermore, blood-product support is essential during periods of marrow suppression, and hematopoeitic growth factors, such as granulocyte colony-stimulating factor and erythropoietin, can be used to reduce the duration of pancytopenia. These interventions work together with therapeutic interventions to provide optimal outcomes for pediatric patients with cancer.
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Rodriguez Cruz, N.I., Madden, R.M., Mullen, C.A. (2005). Supportive Care: Myelosuppression. In: Chan, K.W., Raney, R.B. (eds) Pediatric Oncology. M.D. Anderson Cancer Care Series, vol 4. Springer, Boston, MA. https://doi.org/10.1007/978-0-387-24472-3_15
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DOI: https://doi.org/10.1007/978-0-387-24472-3_15
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