Abstract
Trichomoniasis is the most common sexually transmitted protozoan infection, which has been treated for several decades using nitroimidazoles, mainly metronidazole and tinidazole. Both drugs are still recommended and resistance to them has fortunately been a relatively rare phenomenon. Resistant or tolerant cases exist, however, side effects are also notable. Therefore, novel compounds with different mechanism of action are urgently needed. It is encouraging that several novel and innovative leads have been introduced. They will hopefully help us to develop novel antitrichomonal agents to fight harder against this parasitic disease in the future.
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Funding: Original research of our team is funded by the Academy of Finland and Jane & Aatos Erkko Foundation.
Ethical Approval: This chapter does not contain any studies with human participants or animals performed by the author.
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Parkkila, S. (2021). Trichomonas vaginalis Pharmacological Treatment. In: Vermelho, A.B., Supuran, C.T. (eds) Antiprotozoal Drug Development and Delivery. Topics in Medicinal Chemistry, vol 39. Springer, Cham. https://doi.org/10.1007/7355_2021_123
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DOI: https://doi.org/10.1007/7355_2021_123
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