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Sleep Disorders and Adherence to Inhalation Therapy in Patients with Chronic Obstructive Pulmonary Disease

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Advances in Pulmonary Medicine: Research and Innovations

Part of the book series: Advances in Experimental Medicine and Biology ((NR,volume 1160))

Abstract

Sleep disorders are common in patients with chronic obstructive pulmonary disease (COPD) and are associated with greater disease severity, more frequent exacerbations, greater use of emergency health care, and higher mortality. They may contribute to worsening of COPD course by reducing patients’ adherence to treatment. The aim of this study was to evaluate quality of sleep in COPD patients and to assess the relationship between impaired sleep and adherence to inhalation therapy. The study included 106 COPD patients who were asked to answer the Pittsburgh Sleep Quality Index (PSQI), Epworth Sleepiness Scale (ESS), and Adherence to Refills and Medications Scale (ARMS). Clinical and demographic data were also collected. We found that over 60% of patients presented with sleep disorders (PSQI ≥5) and 75% with daytime sleepiness. None of the patients presented with optimal adherence to pharmacotherapy. Worse adherence was correlated with greater sleep disorders (r = 0.56; p < 0.001). ARMS questionnaire proved to be of high overall internal consistency (Cronbach’s alpha = 0.85). In conclusion, poor quality of sleep coexists with poor adherence to treatment among COPD patients. ARMS was proved to be a reliable tool for the assessment of adherence. Interventions aimed at improving sleep quality may be helpful to improve adherence to inhalation therapy in COPD patients.

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Conflicts of Interests

The authors declared no conflicts of interest in relation to this article.

Ethical Approval

All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards. This study was approved by the local Ethics Committee of Wroclaw Medical University in Poland.

Informed Consent

Written informed consent was obtained from all individual participants included in the study.

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Authors and Affiliations

  1. Division of Surgical Procedures, Department of Clinical Nursing, Faculty of Health Science, Wroclaw Medical University, Wroclaw, Poland

    Mariusz Chabowski

  2. Department of Surgery, Fourth Military Teaching Hospital, Wroclaw, Poland

    Mariusz Chabowski

  3. Department of Clinical Nursing, Faculty of Health Science, Wroclaw Medical University, Wroclaw, Poland

    Judyta Łuczak & Beata Jankowska-Polańska

  4. Faculty of Mechanical Engineering, Wroclaw University of Technology, Wroclaw, Poland

    Krzysztof Dudek

Authors
  1. Mariusz Chabowski
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  2. Judyta Łuczak
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  3. Krzysztof Dudek
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  4. Beata Jankowska-Polańska
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Corresponding author

Correspondence to Mariusz Chabowski .

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Editors and Affiliations

  1. Opole Medical School, Opole, Poland

    Mieczyslaw Pokorski

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Chabowski, M., Łuczak, J., Dudek, K., Jankowska-Polańska, B. (2019). Sleep Disorders and Adherence to Inhalation Therapy in Patients with Chronic Obstructive Pulmonary Disease. In: Pokorski, M. (eds) Advances in Pulmonary Medicine: Research and Innovations. Advances in Experimental Medicine and Biology(), vol 1160. Springer, Cham. https://doi.org/10.1007/5584_2019_345

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