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Pathology of Lung Cancer

  • Chapter
Tumors of the Chest

8.5 Concluding Remarks

In contrast to most other organs, the lungs are prone to a very wide range of epithelial tumors, varying in their location and histology. These tumors show varying degrees of relationship to smoke exposure, with the central carcinomas showing the greatest relationship. The molecular lesions from in these tumors share certain common elements and exhibit characteristic changes. Their precursor lesions also differ, with some being well defined and others being poorly understood because of the difficulty of identifying them prior to surgical resection of an existing tumor. Thus, their natural history is also poorly understood. The advent of newer diagnostic procedures such as fluorescence bronchoscopy and high-resolution CT scanning will aid in their diagnosis and permit us to study their natural history.

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Authors and Affiliations

  1. Department of Pathology and Department of Thoracic/Head and Neck Medical Oncology, The University of Texas M.D. Anderson Cancer Center, Houston, TX, USA

    Ignacio I. Wistuba

  2. The Hamon Center for Therapeutic Oncology Research, Department of Pathology, The University of Texas Southwestern Medical Center, Dallas, TX, USA

    Adi F. Gazdar

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  1. Ignacio I. Wistuba
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Editors and Affiliations

  1. Sotiria General Hospital, Athens Medical School, Athens, Greece

    Konstantinos N. Syrigos MD, PhD

  2. Royal Marsden NHS Trust Hospitals, London, UK

    Christopher M. Nutting MB BA, MD, FRCR

  3. Evangelismos General Hospital, Athens Medical School, Athens, Greece

    Charis Roussos MD, MSc, PhD, MRS, FRCP(C)

  4. Faculty of Medicine, McGill University, Montreal, Canada

    Charis Roussos MD, MSc, PhD, MRS, FRCP(C)

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Wistuba, I.I., Gazdar, A.F. (2006). Pathology of Lung Cancer. In: Syrigos, K.N., Nutting, C.M., Roussos, C. (eds) Tumors of the Chest. Springer, Berlin, Heidelberg . https://doi.org/10.1007/3-540-31040-1_8

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