Heterologous desensitization is a form of desensitization which does not require agonist binding of the receptor. Second messenger dependent kinases such as protein kinase A (PKA) and protein kinase C (PKC) are involved in this form of receptor desensitization. Heterologous desensitization simply depends on the over-all kinase activity which is regulated by many different stimuli.
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© 2004 Springer-Verlag
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(2004). Heterologous Desensitization. In: Encyclopedic Reference of Molecular Pharmacology. Springer, Berlin, Heidelberg. https://doi.org/10.1007/3-540-29832-0_759
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DOI: https://doi.org/10.1007/3-540-29832-0_759
Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-540-42843-5
Online ISBN: 978-3-540-29832-8
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