Skip to main content

Genetics and Environment in the Development of Allergy

  • Chapter
Allergy in Practice
  • 1217 Accesses

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 99.00
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 129.00
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. Barnes KC, Marsh DG (1998) The genetics and complexity of allergy and asthma. Immunol Today 19:325–332

    Article  PubMed  CAS  Google Scholar 

  2. Daser A, Daheshia M, De Sanctis GT (2001) Genetics of allergen-induced asthma. J Allergy Clin Immunol 108:167–174

    Article  PubMed  CAS  Google Scholar 

  3. Blumenthal MN, Björksten M (1997) Genetics of allergy and asthma. Marcel Dekker, New York

    Google Scholar 

  4. Deichmann KA (2001) Asthmagenetik — der immunologische Fingerabdruck. Allergologie 24:330–338

    Google Scholar 

  5. Cooke RA, Van der Veer A (1916) Human sensitization. J Immunol 1:305

    Google Scholar 

  6. Cookson WO, Sharp PA, Faux JA, Hopkin JM (1989) Linkage between immunoglobulin E responses underlying asthma and rhinitis and chromosome 11 q. Lancet 1:1292–1295

    Article  PubMed  CAS  Google Scholar 

  7. CSGA (Collaborative Study on the Genetics of Asthma) (1997) A genome-wide search for asthma susceptibility loci in ethnically diverse populations. Nat Genet 15:389–392

    Article  Google Scholar 

  8. Daniels SE, Bhattacharrya S, James A, Leaves NI, Young A, Hill MR, Faux JA, Ryan GF, le Souef PN, Lathrop GM, Musk AW, Cookson WO (1996) A genome-wide search for quantitative trait loci underlying asthma. Nature 383:247–250

    Article  PubMed  CAS  Google Scholar 

  9. Heinzmann A, Deichmann KA (2001) Genes for atopy and asthma. Curr Opin Allergy Clin Immunol 1:387–392

    Article  PubMed  CAS  Google Scholar 

  10. Hrabe de Angelis M, Flaswinkel H, Fuchs H, Rathkolb B, Soewarto D, Marschall S, Heffner St, Pargent W, Wuensch K, Jung M, Reis A, Richter T, Alessandrini F, Jakob T, Fuchs E, Kolb H, Kremmer E, Schaeble K, Rollinski B, Roscher A, Peters Ch, Meitinger Th, Srom T, Steckler Th, Holsboer F, Klopfstock Th., Gekeler F, Schindewolf C, Jung Th, Avraham K, Behrendt H, Ring J, Zimmer A, Schugart K, Pfeffer K, Wolf E, Balling R (2000) Genomewide, large-scale production of mutant mice by ENU mutagenesis. Nature Genet 25: 444–447

    Article  CAS  Google Scholar 

  11. Huang SK, Zwollo P, Marsh DG (1991) Class II major histocompatibility complex restriction of human cell responses to short ragweed allergen, Amb a V. Eur J Immunol 21:1469–1473

    PubMed  CAS  Google Scholar 

  12. Kjellman NM (1976) Immunglobulin E and atopic allergy in childhood. Linköping Univ Med Diss No 36

    Google Scholar 

  13. Kulig M, Bergmann R, Klettke U, Wahn V, Tacke U, Wahn U, and the Multicenter Allergy Study Group (1999) Natural course of sensitization to food and inhalant allergens during the first 6 years of life. J Allergy Clin Immunol 103: 1173–1179

    Article  PubMed  CAS  Google Scholar 

  14. Marsh DG, Neely JD, Breazeale DR, Ghosh B, Freidhoff LR, Ehrlich-Kautzky E, Schou C, Krishnaswamy G, Beaty TH (1994) Linkage analysis of IL-4 and other chromosome 5q31.1 markers and total serum immunoglobulin E concentrations. Science 264:1152–1156

    PubMed  CAS  Google Scholar 

  15. Menné T, Holm NV (1986) Genetic susceptibility in human allergic contact sensitization. Semin Dermatol 5:301–306

    Google Scholar 

  16. Meyers DA, Postma DS, Panhuysen CIM, Xu J, Amelung PJ, Levitt RC, Bleecker ER (1994) Evidence for a locus regulating total serum IgE levels mapping to chromosome 5. Genomics 23: 464–470

    Article  PubMed  CAS  Google Scholar 

  17. Moffat MF, Hill MR, Cornelis F, Schou C, Faux JA, Young RP, James AL, Ryan G, le Souef P, Musk AW, et al. (1994) Genetic linkage of T-cell receptor α/β complex to specific IgE responses. Lancet 343:1597–1600

    Article  Google Scholar 

  18. Nanavaty U, Goldstein AD, Levine SJ (2001) Polymorphisms in candidate asthma genes. Am J Med Sci 321:11–16

    Article  PubMed  CAS  Google Scholar 

  19. Nickel R, Wahn U, Hizawa N, Maestri N, Duffy DL, Barnes KC, Beyer K, Forster J, Bergmann R, Zepp F, Wahn V, Marsh DG (1997) Evidence for linkage of chromosome 12q15–q24.1 markers to high total serum IgE concentrations in children of the German multicenter allergy study. Genomics 46:159–162

    Article  PubMed  CAS  Google Scholar 

  20. Lee YA, Wahn U, Kehrt R, Tarani L, Businco L, Gustafsson D, Andersson F, Oranje AP, Wolkertstorfer A, v. Berg A, Hoffmann U, Kuster W, Wienker T, Ruschendorf F, Reis A (2000) Chromosome 3 and infantile atopic dermatitis. Nature Genet 26:470–472

    Article  PubMed  CAS  Google Scholar 

  21. Postma DS, Bleecker ER, Amelung PJ, Holroyd KJ, Xu J, Panhuysen C, Meyers DA, Levitt RC (1995) Genetic susceptibility to asthma — bronchial hyperresponsiveness coinherited with a major gene for atopy. N Engl J Med 333:894–900

    Article  PubMed  CAS  Google Scholar 

  22. Rosenwasser LJ, Klemm DJ, Dresback JK, Inamura H, Mascali JJ, Klinnert M, Borish L (1995) Promoter polymorphisms in the chromosome 5 gene cluster in asthma and atopy. Clin Exp Allergy 25:74–78

    Article  PubMed  Google Scholar 

  23. Schnyder UW (1960) Neurodermitis, asthma, rhinitis. Eine genetisch-allergologische Studie. Karger, Basel

    Google Scholar 

  24. Schulz-Larsen F, Holm NV, Henningsen K (1986) Atopic dermatitis: A genetic-epidemiologic study in a population-based twin sample. J Am Acad Dermatol 15:487–494

    Google Scholar 

  25. Shirakawa T, Li A, Dubowitz M, Dekker JW, Shaw AE, Faux JA, Ra C, Cookson WOCM, Hopkin JM (1994) Association between atopy and variants of the subunit of the high-affinity immunoglobulin E receptor. Nature Genet 7:125–129

    Article  PubMed  CAS  Google Scholar 

  26. Vom Eerdewegh P, Little RD, Dapuis J, et al. (2002) Association of the ADAM33 gene with asthma and bronchial hyperresponsiveness. Nature 418:426–430

    Article  PubMed  CAS  Google Scholar 

  27. Wahn U, Lau S, Bergmann R, Kulig M, Forster J, Bergmann K, Bauer CP, Guggenmoos-Holzmann I (1997) Indoor allergen exposure is a risk factor for sensitization during the first three years of life. J Allergy Clin Immunol 99:763–769

    Article  PubMed  CAS  Google Scholar 

  28. Wise F, Sulzberger MB (1934) Editorial remarks in: The 1933 yearbook of dermatology and syphilology. Year Book Medical, Chicago, p 38

    Google Scholar 

  29. Wjst M, Fischer G, Immervoll T, Jung M, Saar K, Rueschendorf F, Reis-Ulbrecht M, Gomolka M, Weiss EH, Jaeger L, Nickel R, Richter K, Kjellman NI, Griese M, von Berg A, Gappa M, Riedel F, Boehle M, van Koningsbruggen S, Schoberth P, Szczepanski R, Dorsch W, Silbermann M, Wichmann HE, et al. (1999) A genome-wide search for linkage to asthma. German Asthma Genetics Group. Genomics 58:1–8

    Article  PubMed  CAS  Google Scholar 

  30. Vercelli D, Baldini M, Martinez F (2001) The monocyte/IgE connection: may polymorphisms in the CD14 gene teach us about IgE regulation? Int Arch Allergy Immunol 124:20–24

    Article  PubMed  CAS  Google Scholar 

  31. Wüthrich B (ed) (1999) The atopy syndrome in the third millennium. Karger, Basel

    Google Scholar 

  32. Wyman M (1872) Autumnal catarrh (hay fever). Hurd & Houghton, Cambridge, p 82

    Google Scholar 

References

  1. Alm JS, Swartz J, Lilja G, Scheynius A, Pershagen G (1999) Atopy in children of families with an anthroposophic lifestyle. Lancet 353:1485–1488

    Article  PubMed  CAS  Google Scholar 

  2. Burr M (ed) (1992) Epidemiology of clinical allergy. Karger, Basel

    Google Scholar 

  3. Gassner-Bachmann B, Wüthrich B (2000) Bauernkinder leiden selten an Heuschnupfen und Asthma. Dtsch med Wschr 125:924–931

    PubMed  CAS  Google Scholar 

  4. The International Study of Asthma and Allergics in Childhood Steering Committee (ISAAC) (1998) World-wide variation of asthma, allergic rhinoconjunctivitis and atopic eczema in prevalence of symptoms. 351:1225–1232

    Google Scholar 

  5. Lewis SA, Weiss ST, Platts-Mills TAE, Syring M, Gold DR (2001) Association of specific allergen sensitization with socioeconomic factors and allergic disease in a population of Boston women. J Allergy Clin Immunol 107:615–622

    Article  PubMed  CAS  Google Scholar 

  6. Mutius E von (1999) Asthma bronchiale und atopische Erkrankungen im Kindesalter. Prävalenz und Risikofaktoren. Dustri, Munich

    Google Scholar 

  7. Olesen AB, Juul S, Birkebaek N, Thestrup-Pedersen K (2001) Association between atopic dermatitis and insulin-dependent diabetes mellitus: a case-control study. Lancet 357:1749–1752

    Article  PubMed  CAS  Google Scholar 

  8. Ring J, Krämer U, Schäfer T, Behrendt H (2001) Why do allergies increase? Curr Opin Immunol 13:201–208

    Google Scholar 

  9. Ring J, Wenning J (eds) (2000) Weißbuch Allergie in Deutschland 2000. Urban und Vogel, Munich

    Google Scholar 

  10. Schäfer T, Ring J (1998) Epidemiologie des atopischen Ekzems. Allergologie 21:259–271

    Google Scholar 

  11. Schäfer T, Böhler E, Ruhdorfer S, Weigl L, Wessner D, Filipiak B, Wichmann HE, Ring J (2001) Epidemiology of contact allergy in adults. Allergy 56:582–585

    Google Scholar 

  12. Schnuch A, et al. (2001) Informationsverbund dermatologischer Kliniken. Prävalenz von Kontaktallergien. Hautarzt 52:582–586

    Article  PubMed  CAS  Google Scholar 

  13. Wahn U, Wichmann HE (eds) (2000) Spezialbericht Allergien. Statistisches Bundesamt, Metzler und Poeschel, Stuttgart

    Google Scholar 

  14. Wichmann HE (1995) Environment, life-style and allergy. The German answer. Allergo J 6:315–316

    Google Scholar 

  15. Wüthrich B (2001) Epidemiologie der Allergien in der Schweiz. Ther Umschau 58:253–258

    Article  Google Scholar 

References

  1. Behrendt H, Nolte D, Ring J (1993) Allergie und Umwelt. In: Vademecum für die Praxis. Bayr. Staatsmin. Landesentwicklung und Umweltfragen, Munich

    Google Scholar 

  2. Behrendt H, Krämer U, Schäfer T, Kasche A, Eberlein-König B, Darsow U, Ring J (2001) Allergotoxicology — a research concept to study the role of environmental pollutants in allergy. Allergy Clin Immunol Int 13:122–128

    Article  Google Scholar 

  3. Behrendt H, Kasche A, Ebner von Eschenbach C, Risse U, Huss-Marp J, Ring J (2001) Secretion of proinflammatory eicosanoid-like substances precedes allergen release frompollen grains in the initiation of allergic sensitization. Int Arch Allergy Immunol 124:121–125

    Article  PubMed  CAS  Google Scholar 

  4. Behrendt H, Ewers HJ, Hüttl RF, Jänicke M, Plaßmann E, Rehbinder E, Sukopp H (1999) (Der Rat der Sachverständigen für Umweltfragen). Umwelt und Gesundheit. Risiken richtig einschätzen. Sondergutachten. Metzler-Poeschel, Stuttgart

    Google Scholar 

  5. Börkstén B (1995) Genetic and environmental interaction in the development of allergy inchildren. Prog Allergy Immunol 3:184–189

    Google Scholar 

  6. Braun-Fahrländer C, Vuille JC, Sennhauser FH, et al. (1997) Respiratory health and long-term exposure to air pollutant in Swiss schoolchildren. SCAR-POL Team. Swiss Study in childhood allergy and respiratory symptoms with respect to air pollution, climate and pollen. Am J Respir Crit Care Med 155:1042–1049

    PubMed  Google Scholar 

  7. Diaz-Sanchez D, Tsiwn A, Fleming J, Saxon A (1997) Combined diesel exhaust particulate and ragweed allergen challenge markedly enhances human in vivo nasal ragweed-specific IgE and skews cytokine production to a helper cell 2-type pattern. J Immunol 158:2406–2413

    PubMed  CAS  Google Scholar 

  8. Eberlein-König B, Przybilla B, Kühnl P, et al. (1998) Influence of airborne nitrogen dioxide or formaldehyde on parameters of skin function and cellular activation in patients with atopic eczema and control subjects. J Allergy Clin Immunol 101:141–143

    Article  PubMed  Google Scholar 

  9. Hirsch T, Weiland SK, von Mutius E, et al. (1999) Inner city air pollution and respiratory health and atopy in children. Eur Respir J 14:669–677

    Article  PubMed  CAS  Google Scholar 

  10. Jörres R, Nowak D, Magnussen H (1996) The effect of ozone exposure on allergen responsiveness in subjects with asthma or rhinitis. Am J Respir Crit Care Med 153:56–64

    PubMed  Google Scholar 

  11. Krämer U, Altmann L, Behrendt H, Dolgner R, Islam MS, Kayers HG, Ring J, Stiller-Winkler R, Turfeld M, Weishoff-Houben M, Willer H, Winneke G (1997) Comparison of the influence of socioeconomic factors on air pollution health effects in West and East Germany. In: Jantunen H (ed) Socioeconomic and cultural factors in air pollution epidemiology. Air pollution epidemiology report series, No. 8. Brussels, EU, pp 41–49

    Google Scholar 

  12. Krämer U, Behrendt H, Dolgner R, et al. (1999) Airway diseases and allergies in East and West Germany children during the first 5 years after reunification: Time trends and the impact of sulphur dioxide and total suspended particles. Int J Epidemiol 28:865–873

    Article  PubMed  Google Scholar 

  13. Krämer U, Koch T, Ranft U, et al. (2000) Traffic-related air pollution is associated with atopy in children living in urban areas. Epidemiology 11:64–70

    Article  PubMed  Google Scholar 

  14. Martinez FD, Antognoni G, Macri F, et al. (1998) Parental smoking enhances bronchial responsiveness in nine-year-old children. Am Rev Respir Dis 138:518–523

    Google Scholar 

  15. Mersch-Sundermann (ed) (1999) Umweltmedizin. Thieme, Stuttgart

    Google Scholar 

  16. Miyamoto T, Takafuji S (1991) Environment and allergy. In: Ring J, Przybilla B (eds) New trends in allergy III. Springer, Berlin Heidelberg New York, pp 459–468

    Google Scholar 

  17. Molfino NA, Wright SC, Katz I, et al. (1991) Effect of low concentrations of ozone on inhaled allergen responses in asthmatic subjects. Lancet 338:199–203

    Article  PubMed  CAS  Google Scholar 

  18. Mutius E von, Weiland SK, Fritzsch C (1998) Increasing prevalence of hay fever and atopy among children in Leipzig, East Germany. Lancet 351:862–866

    Article  Google Scholar 

  19. Riedel F, Kramer M, Scheibenbogen C, Rieger Ch (1984) Effects of S02 exposure on allergic sensitization in the guinea pig. J Allergy Clin Immunol 82:527–534

    Article  Google Scholar 

  20. Riedler J, Edler W, Oberfeld G, Schreuer M (2000) Austrian children living on a farm have less hay fever, asthma and allergic sensitization. Clin Exp Allergy 30:94–200

    Article  Google Scholar 

  21. Ring J, Krämer U, Schäfer T, et al. (1999) Environmental risk factors for respiratory and skin atopy: Results from epidemiologic studies in former East and West Germany. Int Arch Allergy Immunol 118:403–407

    Article  PubMed  CAS  Google Scholar 

  22. Ring J, Behrendt H, Vieluf D (eds) (1997) New trends in allergy IV. Springer, Berlin Heidelberg New York

    Google Scholar 

  23. Ring J (1997) Allergy and modern society: Does “western life style” promote the development of allergies? Int Arch Allergy Immunol 113:7–10

    PubMed  CAS  Google Scholar 

  24. Rusznak C, Devalia JL, Davies RJ (1996) Airway response of asthmatic subjects to inhaled allergen after exposure to pollutants. Thorax 51:1105–1108

    Article  PubMed  CAS  Google Scholar 

  25. Schäfer T, Dirschedl B, Kunz B, et al. (1997) Maternal smoking during pregnancy and lactation increases the risk for atopic eczema in the offspring. J Am Acad Dermatol 36:550–556

    Article  PubMed  Google Scholar 

  26. Schäfer T, Vieluf D, Behrendt H, et al. (1996) Atopic eczema and other manifestations of atopy: results of a study in East and West Germany. Allergy 51:532–539

    PubMed  Google Scholar 

  27. Spieksma FT, Nikkels BH, Dijkman JH (1995) Seasonal appearance of grass pollen allergen in natural, paucimicronic aerosol of various size fractions. Relationship with airborne grass pollen concentration. Clin Exp Allergy 25:234–239

    Article  PubMed  CAS  Google Scholar 

  28. Vialuf D, Beil D, Beauregard K, et al. (1997) Xenobiotics and food allergy: In vivo and in vitro studies in patients with apple allergy. Int Arch Allergy Immunol 113:352–354

    Google Scholar 

  29. Wichmann H (1995) Environment, life-style and allergy: The German answer. Allergo J 6:315–316

    Google Scholar 

  30. Wüthrich B (1989) Epidemiology of the allergic diseases; are they really on the increase? Int Arch Allergy Appl Immunol 90:3–10

    PubMed  Google Scholar 

  31. Zetterström O, Osterman K, Machedo L, Johannson SGO (1981) Another smoking hazard: Raised IgE concentration and increased risk of occupational allergy. Br Med J 283:1215–1217

    Google Scholar 

  32. Ring J (1988) Interview with Natur.

    Google Scholar 

References

  1. Aalbersee RC (2000) Structural biology of allergens. J Allergy Clin Immunol 106:228–238

    Article  Google Scholar 

  2. Baur X, Aschauer H, Dewair M, et al. (1982) Relationship between primary structures and allergenicity of asthma-inducing insect proteins (chironomid hemoglobins). Chest 82:254

    Google Scholar 

  3. Behrendt H, Becker WM (2001) Localization, release and bioavailability of pollen allergens: the influence of environmental factors. Curr Opin Immunol 13:709–715

    Article  PubMed  CAS  Google Scholar 

  4. Bergmann KC/Stiftung Deutscher Polleninformationsdienst (ed) (2001) Pollenbestimmungsbuch der Stiftung Deutscher Polleninformationsdienst. Takt, Paderborn

    Google Scholar 

  5. Bischoff E, Krause-Michel B, Nolte D (1986) Zur Bekämpfung der Hausstaubmilben in Haushalten von Patienten mit Milbenasthma. Allergologie 9:448–457

    Google Scholar 

  6. Breiteneder H, Ferreira F, Reikerstorfer A, et al. (1992) Complementary DNA cloning and expression in Escherichia coli of Aln g I, the major allergen in pollen of alder (Alnus glutinosa). J Allergy Clin Immunol 90:909–917

    Article  PubMed  CAS  Google Scholar 

  7. Celedon JC, Litonjua AA, Ryan L, Platts-Mills T, Weiss ST, Gold DR (2002) Exposure to cat allergen, maternal history of asthma and wheezing in first 5 years of life. Lancet 360:781–782

    Article  PubMed  Google Scholar 

  8. Bronswijk JEMH van (1972) Hausstaub-Ökosystem und Hausstaub-Allergen(e). Acta Allerg 27:219

    Google Scholar 

  9. Chapman MD, Smith AM, Vailes LD, Arruda LK (1997) Recombinant mite allergens. Allergy 52:374–379

    PubMed  CAS  Google Scholar 

  10. Crameri R (1998) Recombinant Aspergillus fumigatus allergens: from the nucleotide sequences to clinical applications. Int Arch Allergy Immunol 115:99–114

    Article  PubMed  CAS  Google Scholar 

  11. Custovic A, Simpson A, Chapman MD, Woodcock A (1998) Allergen avoidance in the treatment of asthma and atopic disorders. Thorax 53:63–72

    PubMed  CAS  Google Scholar 

  12. D’Amato G, Spieksma FTHM (1995) Aerobiologie and clinical aspects of mould allergy in Europe (position paper). Allergy 50:870–877

    PubMed  CAS  Google Scholar 

  13. Ehnert B, Lau-Schadendorf S, Weber A, Buettner P, Schou C, Wahn U (1992) Reducing domestic exposure to dust mite allergen reduces bronchial hyperreactivity in sensitive children with asthma. J Allergy Clin Immunol 90:135–138

    PubMed  CAS  Google Scholar 

  14. Eng PA, Wüthrich B (1994) Silkwaste — a further allergen in the bedroom. Schweiz Rundsch Med Prax 83:402–406

    PubMed  CAS  Google Scholar 

  15. Fahlbusch B, Heinrich J, Gross I, Jäger L, Richter K, Wichmann HE (1999) Allergens in house-dust samples in Germany: results of an East-West German comparison. Allergy 54:1215–1222

    Article  PubMed  CAS  Google Scholar 

  16. Franz JT, et al. (1998) Domestic-Mite-Fauna auf Bauernhöfen in Deutschland. Allergologie 21:371–380

    Google Scholar 

  17. Franz JT, Masuch G, Bergmann KC, Müsken H (2000) Entwicklung und Entwicklungsstadien der Milbe Glycyphagus domesticus (De Geer 1778). Allergologie 23:219–225

    Google Scholar 

  18. Grobe K, Becker WM, Schlaak M, Petersen A (1999) Grass group I allergens (beta-expansins) are novel, papain-related proteinases. Eur J Biochem 263:33–40

    Article  PubMed  CAS  Google Scholar 

  19. Fuchs E (1979) Allergische Atemwegsobstruktion (Allergisches Extrinsic Asthma bronchiale). In: Ulmer WT (ed) Bronchitis, Asthma, Emphysem. Springer, Berlin Heidelberg New York, p 543

    Google Scholar 

  20. Fuckerieder K (1976) Der Graspollengehalt der Luft in Mitteleuropa. Umweltbundesamt Berichte 9:1–85

    Google Scholar 

  21. Hart BJ (1998) Life cycle and reproduction of house-dust mites: environmental factors influencing mite population. Allergy 53[Suppl 48]:13–17

    PubMed  CAS  Google Scholar 

  22. Hausen BM, Vieluf IK (1997) Allergiepflanzen — Pflanzenallergene. Ecomed, Landsberg

    Google Scholar 

  23. Helbing A, Gayer F, Pichler WJ, Brander KA (1998) Mushroom (Basidiomycete) allergy: diagnosis established by skin test and nasal challenge. J Allergy Clin Immunol 102:853–858

    Article  Google Scholar 

  24. Hinze S, Bergmann KC, Lowenstein H, Hansen GN (1996) Differente Schwellenwertkonzentrationen durch das Rinderhaarallergen Bos d 2 bei atopischen und nichtatopischen Landwirten. Pneumologie 50:177–181

    PubMed  CAS  Google Scholar 

  25. Hoppe A, Müsken H, Bergmann KC (1994) Häufigkeit allergischer Atemwegserkrankungen durch Katzenallergene bei Patienten mit und ohne Katzenhaltung. Allergo J 3:96–100

    Google Scholar 

  26. Horak F, Jäger S (1979) Die Erreger des Heufiebers. Urban & Schwarzenberg, Munich

    Google Scholar 

  27. Jorde W (1998) Schimmelpilzallergie. Dustri, Munich

    Google Scholar 

  28. Kersten W, Puls KE (1984) Pollenflugvorhersage. Allergologie 7:84–114

    Google Scholar 

  29. King TP, et al. (1999) Allergen nomenclature. IUIS/WHO Allergen Nomenclature Subcommittee. In: Turner MW, Natrig JB (eds) Immunology Nomenclature. Hogrefe & Huber, Seattle, pp 125–138

    Google Scholar 

  30. Knox RB (1993) Grass pollen, thunderstorms and asthma. Clin Exp Allergy 23:354–359

    Article  PubMed  CAS  Google Scholar 

  31. Köhn FM, Ollert M, Schuppe HC, Rakoski J, Schill WB, Ring J (2000) Spermaallergien. Reproduktionsmedizin 16:183–188

    Article  Google Scholar 

  32. Kraft D, Sehon A (eds) (1993) Molecular biology and immunology of allergens. CRC Press, Boca Raton

    Google Scholar 

  33. Krempl-Lamprecht L (1981) Mykoallergosen durch spezielle Schimmelpilze. In: Borelli S, Düngemann H (eds) Fortschritte der Allergologie und Dermatologie. IMP, Basel, pp 344

    Google Scholar 

  34. Leuschner RM (1983) Pollenzählungen und Informationsdienst über Pollen und Pilzsporen der Luft. Schweiz Ärzteztg 64:1799–1804

    Google Scholar 

  35. Lind P (1985) Purification and partial characterization of two major allergens from the house dust mite Dermatophagoides pteronyssinus. J Allergy Clin Immunol 76:753–761

    Article  PubMed  CAS  Google Scholar 

  36. Partti-Pellinen K, Marttila O, Mäkinen-Kiljunen S, Haahtela T (2000) Occurrence of dog, cat, and mite allergens in public transport vehicles. Allergy 55:65–68

    Article  PubMed  CAS  Google Scholar 

  37. Petersen A, Grobe K, Lindner B, Schlaak M, Bekker WM (1997) Comparison of natural and recombinant isoforms of grass pollen allergens. Electrophoresis 18:819–825

    Article  PubMed  CAS  Google Scholar 

  38. Platt-Mills TA, Vaughan JW, Blumenthal K, Pollart Squillace S, Sporik RB (2001) Serum IgG and IgG4 antibodies to Fel d 1 among children exposed to 20 microg Fel d 1 at home: relevance of a nonallergic modified Th2 response. Int Arch Allergy Immunol 124:126–129

    Article  Google Scholar 

  39. Przybilla B, et al. (1996) Zur gesundheitlichen Gefährdung durch die Allergie vom Soforttyp gegenüber Naturlatex. Positionspapier der Deutschen Gesellschaft für Allergologie und Klinische Immunologie. Allergo J 5:185–192

    Google Scholar 

  40. Rakoski J, Düngemann H (1981) Kreuzsensibilisierung bei Pollen. In: Borelli S, Düngemann H (eds) Fortschritte der Allergologie und Dermatologie. IMP Verlag, Neu-Isenburg, p 116

    Google Scholar 

  41. Reese G, Jeoung BJ, Daul CB, et al. (1997) Characterization of recombinant shrimp allergen Pen a 1 (tropomyosin). Int Arch Allergy Immunol 113:240–242

    Article  PubMed  CAS  Google Scholar 

  42. Ring J, Krempl-Lamprecht L (1987) Aerogene Allergene. Erfassung und Identifzierung. MMW Münch Med Wochenschr 129:145–147

    Google Scholar 

  43. Rudolph R, Kunkel G, Blome B, et al. (1981) Zur Häufigkeit und klinischen Bedeutung von Allergien gegen Tierepithelien. Allergologie 4:230

    Google Scholar 

  44. Salvaggio J, Aukrust L (1981) Mould-induced asthma. J Allergy Clin Immunol 68:327–346

    Article  PubMed  CAS  Google Scholar 

  45. Scheiner O, Kraft D (1995) Basic and practical aspects of recombinant allergens. Allergy 50:384–391

    PubMed  CAS  Google Scholar 

  46. Schramm G, Petersen A, Bufe A, Schlaak M, Bekker WM (1996) Identification and characterization of the major allergens of velvet grass (Holcus lanatus), Hol l 1 and Hol l 5. Int Arch Allergy Immunol 110:354–363

    PubMed  CAS  Google Scholar 

  47. Senti G, Leser C, Lundberg M, Wüthrich B (2000) Allergie asthma to shiitake and oyster mushroom. Allergy 55:975–976

    Article  PubMed  CAS  Google Scholar 

  48. Smith EG (1984) Sampling and identifying allergenic pollens and moulds. Blewstone, San Antonio

    Google Scholar 

  49. Solomon R, Mathews KP (1978) Aerobiology and inhalant allergens. In: Middleton E, et al. (eds) Allergy: Principles and practice. Mosby, St. Louis, pp 1143–1202

    Google Scholar 

  50. Sporik R, Holgate S, Platts-Mills TAE, Cogswell J (1990) Exposure to house-dust mite allergen (Der p 1) and the development of asthma in childhood. N Engl J Med 323:502–507

    Article  PubMed  CAS  Google Scholar 

  51. Stanley RG, Linskens HF (1985) Pollen. Biologie, Biochemie, Gewinnung und Verwendung. Urs Freund, Greifenberg

    Google Scholar 

  52. Stewart GA, McWilliam AS (2001) Endogenous function and biological significance of aeroallergens: an update. Curr Opin Allergy Clin Immunol 1:95–103

    Article  PubMed  CAS  Google Scholar 

  53. Stix E (1981) Pollenkalender: Regionale und jahreszeitliche Verbreitung von Pollen. Wissenschaftliche Verlagsgesellschaft, Stuttgart

    Google Scholar 

  54. Thiel C, Fuchs E (1981) Über korrelative Beziehungen bei Kräuterpollen-und Gewürzallergenen. RAST 3 Berichtsband. Grosse, Berlin, p 178

    Google Scholar 

  55. Tovey ER, Chapman MD, Platts-Mills TA (1981) Mite faeces areamajor source of housedust allergens. Nature 289:592

    Article  PubMed  CAS  Google Scholar 

  56. Tovey ER, Johanson MC, Roche AL, Cobon GS, Baldo BA (1989) Cloning and sequencing of a cDNA expressing a recombinant house dust mite protein that binds human IgE and corresponds to an important low molecular weight allergen. J Exp Med 170:1457–1462

    Article  PubMed  CAS  Google Scholar 

  57. Tovey E, Marks G (1999) Methods and effectiveness of environmental control. J Allergy Clin Immunol 103:179–191

    Article  PubMed  CAS  Google Scholar 

  58. Valenta R, Ball T, Vrtala S, Duchene M, Kraft D, Scheiner O (1994) cDNA cloning and expression of timothy grass (Phleum pratense) pollen profilin in Escherichia coli: comparisonwith birch pollen profilin. Biochem Biophys Res Commun 199:106–118

    Article  PubMed  CAS  Google Scholar 

  59. van Hage-Hamsten M, Johansson E (1998) Clinical and immunological aspects of storagemite allergy. Allergy 53[Suppl 48]:49–53

    PubMed  Google Scholar 

  60. Vieluf D, Przybilla B, Baur X, Ring J (1993) Respiratory allergy and atopic eczema in a thatcher due to storage and house dust mite allergy. Allergy 48:212–214

    PubMed  CAS  Google Scholar 

  61. Voorhorst R, Spieksma-Boezeman MIA, Spieksma FTM (1964) Is a mite (Dermatophagoides sp.) the producer of the housedust allergen? Allergie Asthma 10:329

    PubMed  CAS  Google Scholar 

  62. Wachter R (1982) Pollen-und Sporenflug über der Bundesrepublik Deutschland. Allergopharma Joachim Ganzer, Reinbek, Schriftenreihe 14:147

    Google Scholar 

  63. Wahn U, Peters TP, Siraganian RP (1980) Studies on the allergenic significance and structure of rat serum albumin. J Immunol 125:2544

    PubMed  CAS  Google Scholar 

  64. Weißenbach T, Wüthrich B, Weiher WH (1988) Labortier-Allergien. Eine epidemiologische, allergologische Studie bei Labortier-exponierten Personen. Schweiz Med Wschr 118:930–938

    PubMed  Google Scholar 

  65. Wilken-Jensen K, Gravensen S (eds) (1984) Atlas of moulds in Europe causing respiratory allergy. ASK, Copenhagen

    Google Scholar 

  66. Witkin SS, Jeremias J, Ledger JA (1988) Localized vaginal allergic response in women with recurrent vaginitis. J Allergy Clin Immunol 81:412–416

    Article  PubMed  CAS  Google Scholar 

  67. Wüthrich B, Schmid-Grendelmeier P (1995) Nahrungsmittelallergien. Internist 36:1052–1062

    PubMed  Google Scholar 

  68. Zielonka TM, Charpin D, Berbis P, Luciani P, Casanova D, Vervloet D (1994) Effects of castration and testosterone on Fel d 1 production by sebaceous glands of male cats: I — Immunological assessment. Clin Exp Allergy 24:1169–1173

    PubMed  CAS  Google Scholar 

Download references

Rights and permissions

Reprints and permissions

Copyright information

© 2005 Springer-Verlag Berlin Heidelberg

About this chapter

Cite this chapter

(2005). Genetics and Environment in the Development of Allergy. In: Allergy in Practice. Springer, Berlin, Heidelberg. https://doi.org/10.1007/3-540-26584-8_3

Download citation

  • DOI: https://doi.org/10.1007/3-540-26584-8_3

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-00219-2

  • Online ISBN: 978-3-540-26584-9

  • eBook Packages: MedicineMedicine (R0)

Publish with us

Policies and ethics