Tissue Engineering II

1. Front Matter

   Pages I-XII

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2. Controlling Tissue Microenvironments: Biomimetics, Transport Phenomena, and Reacting Systems

   • Robert J. Fisher, Robert A. Peattie

   Pages 1-73

3. Perfusion Effects and Hydrodynamics

   • Robert A. Peattie, Robert J. Fisher

   Pages 75-156

4. Biopreservation of Cells and Engineered Tissues

   • Jason P. Acker

   Pages 157-187

5. Fabrication of Three-Dimensional Tissues

   • Valerie Liu Tsang, Sangeeta N. Bhatia

   Pages 189-205

6. Engineering Skin to Study Human Disease – Tissue Models for Cancer Biology and Wound Repair

   • Jonathan A. Garlick

   Pages 207-239

7. Gene-Modified Tissue-Engineered Skin: The Next Generation of Skin Substitutes

   • Stelios T. Andreadis

   Pages 241-274

8. Nanostructured Biomaterials for Tissue Engineering Bone

   • Thomas J. Webster, Edward S. Ahn

   Pages 275-308

9. Integration of Technologies for Hepatic Tissue Engineering

   • Yaakov Nahmias, Francois Berthiaume, Martin L. Yarmush

   Pages 309-329

10. Back Matter

    Pages 331-335

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It is our pleasure to present this special volume on tissue engineering in the series Advances in Biochemical Engineering and Biotechnology. Thisvolume re?ects the emergence of tissue engineering as a core discipline of modern biomedical engineering, and recognizes the growing synergies between the technological developments in biotechnology and biomedicine. Along this vein, the focusof thisvolume istoprovide abiotechnology driven perspective on cell engineering fundamentals while highlighting their signi?cance in p- ducing functional tissues. Our aim is to present an overview of the state of the art of a selection of these technologies, punctuated with current applications in the research and development of cell-based therapies for human disease. To prepare this volume, we have solicited contributions from leaders and experts in their respective ?elds, ranging from biomaterials and bioreactors to gene delivery and metabolic engineering. Particular emphasis was placed on including reviews that discuss various aspects of the biochemical p- cesses underlying cell function, such as signaling, growth, differentiation, and communication. The reviews of research topics cover two main areas: cel- lar and non-cellular components and assembly; evaluation and optimization of tissue function; and integrated reactor or implant system development for research and clinical applications. Many of the reviews illustrate how bioche- cal engineering methods are used to produce and characterize novel materials (e. g. genetically engineered natural polymers, synthetic scaffolds with ce- type speci?c attachment sites or inductive factors), whose unique properties enable increased levels of control over tissue development and architecture.

• Biochemical Engineering
• Biomaterial
• Biomedicine
• Biotechnology
• Medical Chemistry
• Tissue Engineering
• biology
• bone
• dynamics
• tissue

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