Conclusions
We have used subtractive hybridisation to identify genomic sequences in a clinical biotype 1A isolate that are absent from a non-clinical biotype 1A strain. We are currently investigating whether these differences contribute to the virulence of the biotype 1A strain.
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References
Bowen, D., Rocheleau, T. A., Blackburn, M, Andreev, O., Golubeva, E., Bhartia, R., and ffrench-Constant, R. H., 1998, Insecticidal toxins from the bacterium Photorhabdus luminescens. Science 280: 2129–2132.
Burnens, A. P., Frey, A., and Nicolet, J, 1996, Association between clinical presentation, biogroups and virulence attributes of Yersinia enterocolitica strains in human diarrhoeal disease. Epidemiol. Infect. 116: 27–34.
Grant, T., Bennett-Wood, V., and Robins-Browne, R. M., 1998, Identification of virulence-associated characteristics in clinical isolates of Yersinia enterocolitica lacking classical virulence markers. Infect. Immun. 66: 1113–1120.
Grant, T., Bennett-Wood, V., and Robins-Browne, R. M., 1999, Characterization of the interaction between Yersinia entoercolitica biotype 1A and phagocytes and epithelial cells in vitro. Infect. Immun. 67: 4367–4375.
Morris, J. G., Jr., Prado, V., Ferreccio, C., Robins-Browne, R. M., Bordun, A.-M., Cayazzo, M., Kay, B. A., and Levine, M. M., 1991, Yersinia enterocolitica isolated from two cohorts of young children in Santiago, Chile: incidence of and lack of correlation between illness and proposed virulence factors. J. Clin. Microbiol. 29: 2784–2788.
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Tennant, S.M., Skinner, N.A., Joe, A., Robins-Browne, R.M. (2004). Yersinia enterocolitica Biotype 1A: Not as Harmless as You Think. In: Skurnik, M., Bengoechea, J.A., Granfors, K. (eds) The Genus Yersinia. Advances in Experimental Medicine and Biology, vol 529. Springer, Boston, MA. https://doi.org/10.1007/0-306-48416-1_24
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DOI: https://doi.org/10.1007/0-306-48416-1_24
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