Pentoxifylline Use for Behçet’s Disease

Conclusions

Behçet’s disease was infrequently encountered in North America, 1.7 cases per rheumatologist, with female to male ratio of 2,5/1. As previously reported^2,3, pentoxifylline was useful in alleviating 50% of oral ulcers and 39% of genital ulcers of Behçet’s patients in North America, at least partially. In conjunction with colchicine, the efficacy significatly improved to 45% for oral ulcers and 48% for genital ulcers (P < 0.001). Pentoxifylline and/or colchicine appeared to have limited efficacy for the other manifestations of Behçet’s disease. Pentoxifilline and/or colchicine was under-utilished by rheumatologists who had patients with Behçet’s disease.