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Diagnosis and treatment of pediatric Cushing’s disease

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Abstract

Cushing’s disease (CD) is rare in the pediatric age range, but may present a diagnostic and therapeutic challenge. Most pediatric endocrinologists have limited experience managing children or adolescents with CD and thus benefit from close consultation with adult colleagues. A diagnostic protocol for investigation is required which broadly follows the model for adult patients. Treatment strategies for CD are described and critically appraised. The management of pediatric CD patients after cure also presents challenges for optimizing growth, bone health, reproduction and body composition from childhood into and during adult life

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Authors and Affiliations

  1. Department of Endocrinology, William Harvey Research Institute, Barts and the London School of Medicine and Dentistry, John Vane Science Centre, Charterhouse Square, London, EC1M 6BQ, UK

    Martin O. Savage, Helen L. Storr, Li F. Chan & Ashley B. Grossman

Authors
  1. Martin O. Savage
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  2. Helen L. Storr
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  3. Li F. Chan
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  4. Ashley B. Grossman
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Correspondence to Martin O. Savage.

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Savage, M.O., Storr, H.L., Chan, L.F. et al. Diagnosis and treatment of pediatric Cushing’s disease. Pituitary 10, 365–371 (2007). https://doi.org/10.1007/s11102-007-0056-4

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