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Identification and Quantitative Determination of the Main Biologically Active Substances in Motherwort Herb by HPLC–Mass Spectrometry

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Pharmaceutical Chemistry Journal Aims and scope

The composition and content of the main biologically active substances (iridoids, flavonoids, hydroxycinnamic acids) of motherwort herb and related preparations were determined using HPLC-UV/MS. The antiradical activity of motherwort raw material and preparations was evaluated in an in vitro DPPH test. The obtained results showed that these methods could be used to evaluate the authenticity and quality of motherwort herb in addition to drugs, extracts, and food supplements based on it.

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Authors and Affiliations

  1. I. M. Sechenov First Moscow State Medical University, 8 Trubetskaya St., Bldg. 2, Moscow, 119991, Russia

    A. A. Zhogova, I. B. Perova, I. A. Samylina & G. V. Ramenskaya

  2. Institute of Nutrition, Russian Academy of Medical Sciences, 2/14 Ust’inskii Proezd, Moscow, 109240, Russia

    A. A. Zhogova, I. B. Perova & K. I. Eller

Authors
  1. A. A. Zhogova
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  2. I. B. Perova
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  3. I. A. Samylina
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  4. K. I. Eller
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  5. G. V. Ramenskaya
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Corresponding author

Correspondence to A. A. Zhogova.

Additional information

Translated from Khimiko-Farmatsevticheskii Zhurnal, Vol. 48, No. 7, pp. 35 – 40, July, 2014.

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Zhogova, A.A., Perova, I.B., Samylina, I.A. et al. Identification and Quantitative Determination of the Main Biologically Active Substances in Motherwort Herb by HPLC–Mass Spectrometry. Pharm Chem J 48, 461–466 (2014). https://doi.org/10.1007/s11094-014-1132-5

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  • DOI: https://doi.org/10.1007/s11094-014-1132-5

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