Skip to main content
SpringerLink
Log in

Characterization of surface modified polyester fabric

  • Published:
Journal of Materials Science: Materials in Medicine Aims and scope Submit manuscript

Abstract

Woven polyethylene terephthalate (PET) fabric has been used in the construction of vascular grafts and sewing ring of prosthetic heart valves. In an effort to improve haemocompatibility and tissue response to PET fabric, a fluoropolymer, polyvinylidine fluoride (PVDF), was coated on PET fabric by dip coating technique. The coating was found to be uniform and no significant changes occurred on physical properties such as water permeability and burst strength. Cell culture cytotoxicity studies showed that coated PET was non-cytotoxic to L929 fibroblast cell lines. In vitro studies revealed that coating improved haemocompatibility of PET fabric material. Coating reduced platelet consumption of PET fabric by 50%. Upon surface modification leukocyte consumption of PET was reduced by 24%. About 60% reduction in partial thromboplastin time (PTT) observed when PET was coated with PVDF. Results of endothelial cell proliferation studies showed that surface coating did not have any substantial impact on cell proliferation. Overall results indicate that coating has potential to improve haemocompatibility of PET fabric without affecting its mechanical performance.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Fig. 1
Fig. 2
Fig. 3
Fig. 4
Fig. 5

Similar content being viewed by others

References

  1. J. Eldrup-Jorgensen, W.C. Mackey, R.J. Connolly, J.L. Mccullough, K. Ramberg, V. Gavris, T.F. O’donnell, A.D. Callow, Am. J. Surg. 150, 185 (1985)

    Article  CAS  PubMed  Google Scholar 

  2. R. Kowalewski, L. Zimnoch, M.Z. Wojtukiewicz, S. Glowinski, J. Glowinski, Blood Coagul. Fibrinolysis 14, 433 (2003)

    Article  PubMed  Google Scholar 

  3. H.P. Greisler, T.H. Schwarcz, J. Ellinger, D.U. Kim, J. Vasc. Surg. 3, 747 (1986)

    Article  CAS  PubMed  Google Scholar 

  4. Y. Noishiki, Y. Tomizawa, Y. Yamane, A. Matsumoto, Artif. Organs 19, 7 (1995)

    Article  CAS  PubMed  Google Scholar 

  5. T. Yoneyama, M. Ito, K. Sugihara, K. Ishihara, N. Nakabayashi, Artif. Organs 24, 23 (2000)

    Article  CAS  PubMed  Google Scholar 

  6. T. Yoneyama, K. Sugihara, K. Ishihara, Y. Iwasaki, N. Nakabayashi, Biomaterials 23, 145 (2002)

    Article  Google Scholar 

  7. K.S. Tweden, H. Harasaki, M. Jones, J.M. Blevitt, W.S. Craig, M. Pierschbacher, M.N. Helmus, J. Heart Valve Dis. 4, S90 (1995)

    PubMed  Google Scholar 

  8. M.K. Dewanjee, D.R. Gross, P. Zhai, S. Lanzo, H. Shim, K. Park, D.J. Schaeffer, A.R. Twardock, J. Heart Valve Dis. 8, 324 (1999)

    CAS  PubMed  Google Scholar 

  9. L.-B. Sun, J. Utoh, S. Moriyama, H. Tagami, K. Okamoto, N. Kitamura, ASAIO J. 47, 325 (2001)

    Article  CAS  PubMed  Google Scholar 

  10. U. Walschus, H. Goldmann, T. Ueberrueck, A. Hoene, L. Wilhelm, M. Schlosser, J. Mater. Sci.: Mater. Med. 19, 1595 (2008)

    Article  CAS  PubMed  Google Scholar 

  11. S.W. Shalaby, U.S. Patent 7,348,364, 2008

  12. J.A. Chinn, J.A. Sauter, R.E. Phillips, W.J. Kao, J.M. Anderson, S.R. Hanson, T.R. Ashton, J. Biomed. Mater. Res. 39, 130 (1998)

    Article  CAS  PubMed  Google Scholar 

  13. L. Pedrini, M. Dondi, A. Magagnoli, F. Magnoni, E. Pisano, E.D. Giudice, M. Santoro, Ann. Vasc. Surg. 15, 679 (2001)

    Article  CAS  PubMed  Google Scholar 

  14. A. Margovsky, H. Parsson, A. Chao, R.S.A. Lord, Eur. J. Vasc. Endovasc. Surg. 23, 39 (2002)

    Article  CAS  PubMed  Google Scholar 

  15. International Standard ISO 7198 (1998 E), Cardiovascular implants—tubular vascular prostheses

  16. International Standard ISO 10993-5 (1999), Biological evaluation of medical devices—Part 5: Tests for in vitro cytotoxicity

  17. International Standard ISO 10993-4 (2002 E), Biological evaluation of medical devices—Part 4: Selection of tests for interactions with blood

Download references

Acknowledgements

Authors wish to thank the Director, SCTIMST for providing facilities for conducting the study. Authors are grateful to Dr. T.V. Kumari and Dr. Lissy Krishnan for their inputs. The research project received financial assistance through a TDF-funding.

Author information

Authors and Affiliations

  1. Biomedical Technology Wing, Sree Chitra Tirunal Institute for Medical Sciences and Technology, Trivandrum, 695012, Kerala, India

    Roy Joseph, R. Shelma, A. Rajeev & C. V. Muraleedharan

Authors
  1. Roy Joseph
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. R. Shelma
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. A. Rajeev
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. C. V. Muraleedharan
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Roy Joseph.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Joseph, R., Shelma, R., Rajeev, A. et al. Characterization of surface modified polyester fabric. J Mater Sci: Mater Med 20 (Suppl 1), 153–159 (2009). https://doi.org/10.1007/s10856-008-3502-6

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s10856-008-3502-6

Keywords

Search

Navigation