A new indene derivative named phomoindene A (1) and four known compounds were isolated from the marine fungus Phomopsis sp. (No. GX7-4A). Their structures were determined by spectroscopic methods, mainly 1D and 2D NMR. Preliminary pharmacological tests revealed that phomoindene A exhibited little cytotoxic activity towards KB, KBv 200, and MCF-7 cell lines.
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Acknowledgment
We thank Prof. Lifu Wu and Dr. Jie Yuan for providing pharmacological data. This research was supported by the National Natural Science Foundation of China (20772162, 20572136), the 863 Foundation of China (2007AA09Z448, 2006AA09Z422), the Science Foundation of Guangdong Province, China (2007A032600001), and the Star Lake Biotechnology Co., Inc., Zhaoqing, Guangdong, China.
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Published in Khimiya Prirodnykh Soedinenii, No. 2, pp. 192–193, March–April, 2010.
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Chen, Y., Pan, J., Xu, F. et al. A new indene derivative from the marine fungus Phomopsis SP. (No. GX7-4A). Chem Nat Compd 46, 230–232 (2010). https://doi.org/10.1007/s10600-010-9576-7
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DOI: https://doi.org/10.1007/s10600-010-9576-7